Труды сотрудников ИЛ им. В.Н. Сукачева СО РАН

/ R. R. Khaydarov [et al.] // NATO Science for Peace and Security Series C: Environmental Security. - 2011. - Vol. 112. - P117-127, DOI 10.1007/978-94-007-1235-5_9 . -
Аннотация: The significant growth in applications of silver nanoparticles across -various branches of industry as well as in consumer products has caused concerns that nanosilver may have a toxic effect on the environment and human health and may have implications for eco-terorism. This paper presents research on antimicrobial effects of silver nanoparticles. We studied the cytotoxicity of silver nanoparticles via an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromid) assay that measures cell activity through the mitochondrial cleavage of a molecule that exhibits a change of colour that can be measured spectrophotometrically. NIH-3T3 (Swiss mouse embryo), HEP-G2 (human hepatocellular carcinoma), A-549 (human lung carcinoma), PC-12 (rat adrenal pheochromocytoma), and Colo-320 (human colon adenocarcinoma) cells were chosen in order to study different possible absorption paths of nanoparticles into the organism and various areas of particle accumulation in the body. The obtained MTT test results have shown that silver nanoparticles with concentrations of ∼1-10 ppm entering the body from air or liquid suspensions can present a potential risk to human health. © Springer Science+Business Media B.V. 2011.

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Держатели документа:
Institute of Nuclear Physics, Tashkent, Uzbekistan
V.N. Sukachev Institute of Forest SB RAS, Krasnoyarsk, Russian Federation
Institute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University, Hannover, Germany
Department of Environmental Engineering, Yonsei University, Wonju, South Korea

Доп.точки доступа:
Khaydarov, R.R.; Khaydarov, R.A.; Evgrafova, S.; Wagner, S.; Cho, S.Y.

[] / R. R. Khaydarov [et al.] // Silver Nanoparticles: Prop., Charact. and Appl. - 2011. - P328-339 . -
Аннотация: The minimum inhibitory concentrations (MICs) assays conducted for E. coli, S. aureus, B. subtilis and P. phoeniceum have shown that the antimicrobial activity of silver ions was superior to that of silver nanoparticles. As silver nanoparticles can be more suitable in some bactericidal applications than silver ions, the efficacy of nanosilver as an antimicrobial agent against a range of microbes on the surface of water paints and cotton fabrics has been studied. The cytotoxicity of silver nanoparticles has been studied using NIH-3T3, HEP-G2, A-549, PC-12, and Colo-320 cells via the MTT ((3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromid) test. The MTT test results obtained have shown that silver nanoparticles in concentrations of ~1-10 ppm entering the body from air or liquid suspensions can present a potential risk to human health. However, silver nanoparticles as a commercially viable addition to be used in paint and textile industry are unlikely to present a direct health risk. © 2010 Nova Science Publishers, Inc. All rights reserved.

Scopus

Держатели документа:
Institute of Nuclear Physics, Tashkent, Uzbekistan
Department of Materials Engineering, CSIRO Division of Process Science and Engineering, Monash University, Clayton, VIC, Australia
V.N. Sukachev Institute of Forest SB RAS, Krasnoyarsk, Russian Federation
Dept. of Environmental Engineering, Yonsei University, Wonju, South Korea
Institute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University, Germany

Доп.точки доступа:
Khaydarov, R.R.; Khaydarov, R.A.; Estrin, Y.; Evgrafova, S.; Cho, S.Y.; Wagner, S.