[Текст] : сборник / Department of Environmental Toxicology and the Health Research Center,Southern University and A & M College (108 Fisher Hall James L. Hunt StreetBaton RougeLA70813), Department of Chemistry,Louisiana State University (USA), Louisiana State University,Baton RougeLA70808, Department of Medicine and Pharmacology,Tulane University School of Medicine (Tulane AveNew OrleansLA70112), Department of Internal Medicine and the Davis Heart & Lung Research Institute,Ohio State University (473 West 12th AveColumbusOH43210USA) ; ed. R. M. Uppu [et al.]. - 2nd ed. - New York [et al.] : Humana press : Springer Science+Business Media, 2010. - XVI,480 p. : ill. ; 26 cm. - (Methods in molecular biology, ISSN 1064-3745 ; 610) (Springer protocols). - Bibliogr. at the end of the chapters. - Subject ind.: p. 469-480. -
ISBN 978-1-58829-710-5 (в пер.) : 0.00
Перевод заглавия: Свободные радикалы и антиоксидантные протоколы
Перевод заглавия: Свободные радикалы и антиоксидантные протоколы
ББК Е072.3я43 + Е902.34я43 + Р281.77я43
Аннотация: This cutting-edge and updated book offers methods for the rapid detection of RONs and redox stress. It includes in-depth analysis of natural and synthetic antioxidants, and also of DNA oxidation, oxidative lipidomics, and biomarkers. In recent years there has been a growing demand to achieve more rapid and accurate detection of RONs (reactive oxygen and nitrogen species), which affect normal physiological processes and pathological conditions, and also of redox stress. In Free Radicals and Antioxidant Protocols, Second Edition, world-renowned researchers respond to this need, considering the most recent analytical and technological aspects of the detection and determination of RONs, and of oxidative, nitrative, nitrosative, and redox stress in biological systems in vivo and in vitro. Chapters include protocols to establish biomarkers for the oxidative stress-induced genetic damage in cellular and animal models, provide novel methods and technologies for analyzing peroxidized lipids, describe techniques for gene therapy, and present methods of EPR imaging of free radicals and oxygen in vivo. Composed in the highly successful Methods in Molecular Biology series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and user-friendly, Free Radicals and Antioxidant Protocols, Second Edition, is an essential guide for the novice and expert researcher alike.
оглавление Доп.точки доступа: Uppu, Rao M. \ed.\; Murthy, S.N. \ed.\; Pryor, W.A. \ed.\; Parinandi, N.L. \ed.\; Department of Environmental Toxicology and the Health Research Center,Southern University and A & M College (108 Fisher Hall James L. Hunt StreetBaton RougeLA70813); Department of Chemistry,Louisiana State University (USA). Louisiana State University,Baton RougeLA70808; Department of Medicine and Pharmacology,Tulane University School of Medicine (Tulane AveNew OrleansLA70112); Department of Internal Medicine and the Davis Heart & Lung Research Institute,Ohio State University (473 West 12th AveColumbusOH43210USA)
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