Сводный каталог книг

[Текст] : сборник / ed.: R. R. Dietert, R. W. Luebke. - New York [et al.] : Humana press, 2012. - XV,451 p. : ill. ; 24 cm. - (Molecular and integrative toxicology). - Bibliogr. at the end of the chapters. - Ind.: p. 443-451. - ISBN 978-1-61779-811-5 (в пер.) : 0.00
Перевод заглавия: Иммунотоксичность, иммунная дисфункция и хронические заболевания
   Перевод заглавия: Иммунотоксичность, иммунная дисфункция и хронические заболевания

ГРНТИ

76.03

ББК Р252.3я43

Аннотация: Immunotoxicity, Immune Dysfunction, and Chronic Disease is among the first books to illustrate the linkage between environmental risk factors (e.g., chemicals, drugs, diet, lifestyles), environmentally-induced immune dysfunction and the full range of resulting chronic diseases and conditions. There is a detailed discussion of specific immune-based chronic diseases and conditions that emerge in children and adults and affect different physiological systems. The book integrates a consideration of risk factors and specific immunotoxic alterations with disease outcomes. A significant number of diseases and conditions are discussed, such as systemic allergic diseases affecting the lung, skin and gastrointestinal tract, systemic autoimmune diseases (type 1 diabetes,multiple sclerosis and lupus) and chronic conditions that are not traditionally associated with chemically-mediated immunomodulation (depression, frailty, and atherosclerosis). Inflammatory dysregulation is a common thread that connects many of the diseases and conditions discussed in this book and provides a central focus. Individual chapters are organized by disease with the addition of chapters that provide integrative information on: 1) patterns of disease comorbidities and 2) the safety testing of chemicals and drugs to reduce the risk of immune dysfunction. Each chapter contains a summary of key points as well as recommendations when appropriate. The book stresses the benefits of identifying the environmental risk factors of immune-mediated chronic disease and the potential to reduce the prevalence of these diseases and conditions. This volume is a valuable resource for researchers, clinicians, risk assessors and regulators and students. Keywords: Chronic disease - Immune dysfunction - Immune system - Immunology - Immunotoxicity - Robert Luebke - Rodney R. Dietert - Toxicology

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Dietert, Rodney R. \ed.\; Luebke, Robert W. \ed.\
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