[Text] : статья / G. V. Makarskaya, S. V. Tarskikh, E. G. Turitsyna // Russian Agricultural Sciences. - 2011. - Vol. 37, № 3. - p. 254-257, DOI 10.3103/S1068367411030128
. - ISSN 1068-3674
Полный текст
Держатели документа:
ИВМ СО РАН : 660036, Красноярск, Академгородок, 50, стр.44
Доп.точки доступа:
Tarskikh, S.V.; Turitsyna, E.G.; Макарская, Галина Владимировна
Труды сотрудников ИВМ СО РАН
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Найдено документов в текущей БД: 11
Luminol-Lucigenin-Dependent Chemiluminescence of Chicken Whole-Blood Cells during Postnatal Ontogeny
Peculiarities of functional activity of the peripheral blood cells of fishes of the middle section of the krasnoyarsk reservoir in summer period
[Text] / G.V. Makarskaya, S.V. Tarskikh // Hydrobiological Journal. - 2012. - Vol. 48, Is. 1. - pp. 83-90, DOI 10.1615/HydrobJ.v48.i1.100
. - ISSN 0018-8166
Кл.слова (ненормированные):
Active oxygen forms -- Blood -- Chemiluminescence -- Fishes -- Functional activity -- Non-specific resistance -- Phagocytosis -- blood -- fish -- functional change -- metabolism -- monitoring -- oxygen -- phagotrophy -- quantitative analysis -- reservoir -- seasonal variation -- spawning -- summer -- water level -- Krasnoyarsk [Russian Federation] -- Russian Federation -- Pisces
Аннотация: Paper deals with results of monitoring of the quantitative and functional characteristics of the peripheral blood cells of different fish species of the middle section of the Krasnoyarsk reservoir over the years 2000-2009. Seasonal dynamics of the oxygen metabolism of the blood cells of different fishes was characterized by similar changes of the non-specific resistance in the spawning and post-spawning period under different level of the water filling of the reservoir. В© 2012 Begell House, Inc.
Scopus
Доп.точки доступа:
Makarskaya, G.V.; Макарская, Галина Владимировна; Tarskikh, S.V.
Кл.слова (ненормированные):
Active oxygen forms -- Blood -- Chemiluminescence -- Fishes -- Functional activity -- Non-specific resistance -- Phagocytosis -- blood -- fish -- functional change -- metabolism -- monitoring -- oxygen -- phagotrophy -- quantitative analysis -- reservoir -- seasonal variation -- spawning -- summer -- water level -- Krasnoyarsk [Russian Federation] -- Russian Federation -- Pisces
Аннотация: Paper deals with results of monitoring of the quantitative and functional characteristics of the peripheral blood cells of different fish species of the middle section of the Krasnoyarsk reservoir over the years 2000-2009. Seasonal dynamics of the oxygen metabolism of the blood cells of different fishes was characterized by similar changes of the non-specific resistance in the spawning and post-spawning period under different level of the water filling of the reservoir. В© 2012 Begell House, Inc.
Scopus
Доп.точки доступа:
Makarskaya, G.V.; Макарская, Галина Владимировна; Tarskikh, S.V.
Nanodiamonds as Carriers for Address Delivery of Biologically Active Substances
[Text] / K.V. Purtov [et al.] // Nanoscale Res. Lett. - 2010. - Vol. 5, Is. 3. - pp. 631-636, DOI 10.1007/s11671-010-9526-0. - Cited References: 24. - This work was supported by the Program # 27 for Basic Research of the Presidium of RAS (project 3.6.3).
. - ISSN 1931-7573
РУБ Nanoscience & Nanotechnology + Materials Science, Multidisciplinary + Physics, Applied
Аннотация: Surface of detonation nanodiamonds was functionalized for the covalent attachment of immunoglobulin, and simultaneously bovine serum albumin and Rabbit Anti-Mouse Antibody. The nanodiamond-IgG(I125) and RAM-nanodiamond-BSA(I125) complexes are stable in blood serum and the immobilized proteins retain their biological activity. It was shown that the RAM-nanodiamond-BSA(I125) complex is able to bind to the target antigen immobilized on the Sepharose 6B matrix through antibody-antigen interaction. The idea can be extended to use nanodiamonds as carriers for delivery of bioactive substances (i.e., drugs) to various targets in vivo.
Доп.точки доступа:
Purtov, K.V.; Petunin, A.I.; Burov, A.E.; Буров, Андрей Ефимович; Puzyr, A.P.; Bondar, V.S.
Рубрики:
ANTICANCER DRUGS
NANOPARTICLES
ADSORPTION
PARTICLES
PROTEINS
Кл.слова (ненормированные):
Nanodiamonds -- Ligand -- Protein immobilization -- Nanocarrier -- Targeted delivery
ANTICANCER DRUGS
NANOPARTICLES
ADSORPTION
PARTICLES
PROTEINS
Кл.слова (ненормированные):
Nanodiamonds -- Ligand -- Protein immobilization -- Nanocarrier -- Targeted delivery
Аннотация: Surface of detonation nanodiamonds was functionalized for the covalent attachment of immunoglobulin, and simultaneously bovine serum albumin and Rabbit Anti-Mouse Antibody. The nanodiamond-IgG(I125) and RAM-nanodiamond-BSA(I125) complexes are stable in blood serum and the immobilized proteins retain their biological activity. It was shown that the RAM-nanodiamond-BSA(I125) complex is able to bind to the target antigen immobilized on the Sepharose 6B matrix through antibody-antigen interaction. The idea can be extended to use nanodiamonds as carriers for delivery of bioactive substances (i.e., drugs) to various targets in vivo.
Доп.точки доступа:
Purtov, K.V.; Petunin, A.I.; Burov, A.E.; Буров, Андрей Ефимович; Puzyr, A.P.; Bondar, V.S.
Динамика функциональной активности клеток неспецифической резистентности в процессе онтогенеза у рыб Красноярского водохранилища
[Текст] : статья / Г. В. Макарская, С. В. Тарских // Проблемы патологии, иммунологии и охраны здоровья рыб и других гидробионтов. - 2015. - С. 190-198
. - ISBN 978-5-906682-37-6
Перевод заглавия: Dynamics of functional activity of nonspecific resistency cells of fishs of Krasnoyarsk reservoir during ontogenesis
Аннотация: The age-specific dynamics of functional activity of fish blood cells, estimated by kinetics of ROS generation by antigene-activated immunocompetent cells in system of whole blood at all surveyed kinds of the fishes is characterized. The intensity and volume of ROS generation of blood cells are changing with increase in age and the maximum of reaction is displaced to more later time, that probably testifies about decreasing of activity of pro- and antioxydant enzymes of cells and factors of a cellular environment. The first 3 years of a life at the perch, 6 years at the roach and 8 years at the bream are characterized increase in activity of production ROS, thus distribution of volume of production ROS directly connected with phagocytosis, is specific to each kind and changes in process of aging of individuals.
РИНЦ,
Источник статьи
Держатели документа:
2Международный научный центр исследований экстремальных состояний организма при Президиуме Красноярского научного центра СО РАН
Институт вычислительного моделирования СО РАН
Доп.точки доступа:
Тарских, С.В.; Makarskaya G.V.; IV Международная конференция "Проблемы патологии, иммунологии и охраны здоровья рыб и других гидробионтов" (2015 ; 24.09 - 27.09 ; Борок)
Перевод заглавия: Dynamics of functional activity of nonspecific resistency cells of fishs of Krasnoyarsk reservoir during ontogenesis
Аннотация: The age-specific dynamics of functional activity of fish blood cells, estimated by kinetics of ROS generation by antigene-activated immunocompetent cells in system of whole blood at all surveyed kinds of the fishes is characterized. The intensity and volume of ROS generation of blood cells are changing with increase in age and the maximum of reaction is displaced to more later time, that probably testifies about decreasing of activity of pro- and antioxydant enzymes of cells and factors of a cellular environment. The first 3 years of a life at the perch, 6 years at the roach and 8 years at the bream are characterized increase in activity of production ROS, thus distribution of volume of production ROS directly connected with phagocytosis, is specific to each kind and changes in process of aging of individuals.
РИНЦ,
Источник статьи
Держатели документа:
2Международный научный центр исследований экстремальных состояний организма при Президиуме Красноярского научного центра СО РАН
Институт вычислительного моделирования СО РАН
Доп.точки доступа:
Тарских, С.В.; Makarskaya G.V.; IV Международная конференция "Проблемы патологии, иммунологии и охраны здоровья рыб и других гидробионтов" (2015 ; 24.09 - 27.09 ; Борок)
Возрастные изменения функциональной активности клеток органов cиcтемы иммуногенеза цыплят
[Текст] : статья / Г. В. Макарская, С. В. Тарских, Е. Г. Турицына // Наука и образование : материалы XIV международной научно-практической конференции. - Красноярск : Красноярский государственный аграрный университет, 2015. - Ч. II. - С. 251-256
Аннотация: The natural age dynamics of the volume of ROS generation and an index of activation of cells was detected by the chemiluminescent analysis of functional activity of cells of peripheral blood and immunocompetent bodies of chickens of early age.
РИНЦ,
Источник статьи
Держатели документа:
Институт вычислительного моделирования Сибирского отделения Российской академии наук
Красноярский государственный аграрный университет
Международный научный центр исследований экстремальных состояний организма при Президиуме Федерального государственного бюджетного учреждения науки Красноярский научный центр СО РАН
Доп.точки доступа:
Тарских, С.В.; Турицына, Е.Г.; Makarskaya G.V.; Наука и образование: опыт, проблемы, перспективы развития (2015 ; 22.04 - 23.04 ; Красноярск)
Аннотация: The natural age dynamics of the volume of ROS generation and an index of activation of cells was detected by the chemiluminescent analysis of functional activity of cells of peripheral blood and immunocompetent bodies of chickens of early age.
РИНЦ,
Источник статьи
Держатели документа:
Институт вычислительного моделирования Сибирского отделения Российской академии наук
Красноярский государственный аграрный университет
Международный научный центр исследований экстремальных состояний организма при Президиуме Федерального государственного бюджетного учреждения науки Красноярский научный центр СО РАН
Доп.точки доступа:
Тарских, С.В.; Турицына, Е.Г.; Makarskaya G.V.; Наука и образование: опыт, проблемы, перспективы развития (2015 ; 22.04 - 23.04 ; Красноярск)
Dielectric specifics of the blood in unstable angina: New additional test for acute myocardial ischemia diagnostics
/ Y. I. Grinshtein [и др.] // Russ. J. Cardiol. - 2015. - Vol. 125, Is. 9. - С. 12-18, DOI 10.15829/1560-4071-2015-09-12-18
. - ISSN 1560-4071
Кл.слова (ненормированные):
Dielectric Fourierspectroscopy of the blood -- Myocardial ischemia -- NSTEACS -- Unstable angina
Аннотация: Aim. To study blood dielectric properties of patients with unstable angina (UA) for the development of novel additional diagnostic criteria for acute myocardial ischemia. Material and methods. Totally, 61 patient studied with non-ST-elevation acute coronary syndrome (NSTEACS), of those 40 patients having on ECG the changes of ischemic type, 21 patient with ACS without ECG changes. In all patients troponin T was negative in single measurement. Comparison group consisted of the stable angina patients II FC (n=13). Controls consisted of 30 healthy donors of blood transfusion center; to 59% patients with preliminary diagnosis NSTEACS (n=61) diagnostic coronary angiography was don (CAG). To all patients we performed study of dielectric properties of the blood by the Fourier-spectroscopy method. Results. Dielectric properties of the blood in NSTEACE/UA, during the first hours of pain onset significantly differ from those in stable angina and controls. In 26% of patients dielectric properties of the blood get back later than positive changes of ECG occur (ST return to isoline). Conclusion. Diagnostic test for acute myocardial ischemia, together with ECGdiagnostics and clinical picture makes it possible, in short time, to perform expressdiagnostics of myocardial ischemia when NSTEACS/UA is suspected, especially in comorbidity patients having the same ST depression on ECG, caused by LV hypertrophy. © 2015, Silicea-Poligraf. All rights reserved.
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Держатели документа:
SBEI HPE Krasnoyarsk State Medical University n. a. Voyno-Yasenetskiy V.F. of the HM, Krasnoyarsk, Russian Federation
International Science Center for the Research of Extreme States of the Body, Head of Krasnoyarsk Scientific Center of Siberian, Department of RAS, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Grinshtein, Y. I.; Sukhovolsky, V. G.; Andina, L. A.; Grinshtein, I. Y.; Kovalev, A. V.
Кл.слова (ненормированные):
Dielectric Fourierspectroscopy of the blood -- Myocardial ischemia -- NSTEACS -- Unstable angina
Аннотация: Aim. To study blood dielectric properties of patients with unstable angina (UA) for the development of novel additional diagnostic criteria for acute myocardial ischemia. Material and methods. Totally, 61 patient studied with non-ST-elevation acute coronary syndrome (NSTEACS), of those 40 patients having on ECG the changes of ischemic type, 21 patient with ACS without ECG changes. In all patients troponin T was negative in single measurement. Comparison group consisted of the stable angina patients II FC (n=13). Controls consisted of 30 healthy donors of blood transfusion center; to 59% patients with preliminary diagnosis NSTEACS (n=61) diagnostic coronary angiography was don (CAG). To all patients we performed study of dielectric properties of the blood by the Fourier-spectroscopy method. Results. Dielectric properties of the blood in NSTEACE/UA, during the first hours of pain onset significantly differ from those in stable angina and controls. In 26% of patients dielectric properties of the blood get back later than positive changes of ECG occur (ST return to isoline). Conclusion. Diagnostic test for acute myocardial ischemia, together with ECGdiagnostics and clinical picture makes it possible, in short time, to perform expressdiagnostics of myocardial ischemia when NSTEACS/UA is suspected, especially in comorbidity patients having the same ST depression on ECG, caused by LV hypertrophy. © 2015, Silicea-Poligraf. All rights reserved.
Scopus,
Смотреть статью
Держатели документа:
SBEI HPE Krasnoyarsk State Medical University n. a. Voyno-Yasenetskiy V.F. of the HM, Krasnoyarsk, Russian Federation
International Science Center for the Research of Extreme States of the Body, Head of Krasnoyarsk Scientific Center of Siberian, Department of RAS, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Grinshtein, Y. I.; Sukhovolsky, V. G.; Andina, L. A.; Grinshtein, I. Y.; Kovalev, A. V.
Secret life of tiny blood vessels: Lactate, scaffold and beyond
/ V. Salmin [et al.] // (26 April 2017 through 28 April 2017 : Springer Verlag, 2017. - Vol. 10208 LNCS. - P591-601, DOI 10.1007/978-3-319-56148-6_53
. -
Кл.слова (ненормированные):
Angiogenesis in vitro -- Brain microvessel endothelial cells -- Form factor -- Fractal dimension -- Gelatin scaffold -- Bioinformatics -- Biomedical engineering -- Blood vessels -- Brain -- Cells -- Cytology -- Endothelial cells -- Fractal dimension -- Fractals -- Angiogenesis -- Bio-scaffolds -- Form factors -- In-vitro -- Microenvironments -- Microvessel -- Microvessels -- Primary culture -- Scaffolds (biology)
Аннотация: We studied the model of cerebral angiogenesis in vitro using lactate-releasing gelatin bioscaffolds and primary culture of brain endothelial cells. We found that development of microvessels from actively proliferating rat brain microvessels endothelial cells was greatly modified by the presence of lactate at the surface of the scaffold with different lactate-releasing ability. Fractal dimension of newly-established vessel loops allows precise characterizing the local microenvironment supporting cell growth on various types of gelatin scaffolds. © Springer International Publishing AG 2017.
Scopus,
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WOS
Держатели документа:
Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Salmin, V.; Morgun, A.; Khilazheva, E.; Pisareva, N.; Boitsova, E.; Lavrentiev, P.; Sadovsky, M.G.; Садовский, Михаил Георгиевич; Salmina, A.
Кл.слова (ненормированные):
Angiogenesis in vitro -- Brain microvessel endothelial cells -- Form factor -- Fractal dimension -- Gelatin scaffold -- Bioinformatics -- Biomedical engineering -- Blood vessels -- Brain -- Cells -- Cytology -- Endothelial cells -- Fractal dimension -- Fractals -- Angiogenesis -- Bio-scaffolds -- Form factors -- In-vitro -- Microenvironments -- Microvessel -- Microvessels -- Primary culture -- Scaffolds (biology)
Аннотация: We studied the model of cerebral angiogenesis in vitro using lactate-releasing gelatin bioscaffolds and primary culture of brain endothelial cells. We found that development of microvessels from actively proliferating rat brain microvessels endothelial cells was greatly modified by the presence of lactate at the surface of the scaffold with different lactate-releasing ability. Fractal dimension of newly-established vessel loops allows precise characterizing the local microenvironment supporting cell growth on various types of gelatin scaffolds. © Springer International Publishing AG 2017.
Scopus,
Смотреть статью,
WOS
Держатели документа:
Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Salmin, V.; Morgun, A.; Khilazheva, E.; Pisareva, N.; Boitsova, E.; Lavrentiev, P.; Sadovsky, M.G.; Садовский, Михаил Георгиевич; Salmina, A.
An impact of severe preeclampsia on cardiovascular system adaptation of newborns in early neonatal period
/ O. Kireeva [et al.] // (26 April 2017 through 28 April 2017 : Springer Verlag, 2017. - Vol. 10208 LNCS. - P517-523, DOI 10.1007/978-3-319-56148-6_46
. -
Кл.слова (ненормированные):
Blood pressure -- Correlation -- Dynamics -- Model -- Bioinformatics -- Biomedical engineering -- Blood pressure -- Correlation methods -- Dynamics -- Models -- K-means -- Preeclampsia -- Verification data -- Cardiovascular system
Аннотация: Some preliminary results toward the relation of various factors of age adaptation in early neonatal period, and parameters of the development of cardiovascular system are present. It was fond both healthy babies (verification data set) and those born by mothers with severe preeclampsia are stably divided into two classes, by K-means. Functional and clinical differences between the classes still require more detailed investigation. © Springer International Publishing AG 2017.
Scopus,
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WOS
Держатели документа:
Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation
Kemerovo Regional Perinatal Center, Oktjabrsky pr. 22, Kemerovo, Russian Federation
Доп.точки доступа:
Kireeva, O.; Bushmelev, E.; Emelianchik, E.; Salmina, A.; Sadovsky, M.
Кл.слова (ненормированные):
Blood pressure -- Correlation -- Dynamics -- Model -- Bioinformatics -- Biomedical engineering -- Blood pressure -- Correlation methods -- Dynamics -- Models -- K-means -- Preeclampsia -- Verification data -- Cardiovascular system
Аннотация: Some preliminary results toward the relation of various factors of age adaptation in early neonatal period, and parameters of the development of cardiovascular system are present. It was fond both healthy babies (verification data set) and those born by mothers with severe preeclampsia are stably divided into two classes, by K-means. Functional and clinical differences between the classes still require more detailed investigation. © Springer International Publishing AG 2017.
Scopus,
Смотреть статью,
WOS
Держатели документа:
Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation
Kemerovo Regional Perinatal Center, Oktjabrsky pr. 22, Kemerovo, Russian Federation
Доп.точки доступа:
Kireeva, O.; Bushmelev, E.; Emelianchik, E.; Salmina, A.; Sadovsky, M.
591.11
А 64
А 64
АНАЛИЗ ФУНКЦИОНАЛЬНОЙ АКТИВНОСТИ КЛЕТОК КРОВИ КУР ПРИ ВАКЦИНАЦИЯХ
[Текст] : статья / Галина Владимировна Макарская, Светлана Вениаминовна Тарских, Евгения Геннадьевна Турицына // Ветеринарная патология. - 2013. - № 3. - С. 65-69
. - ISSN 1682-5616
Кл.слова (ненормированные):
иммунизация -- фагоцитоз -- функциональная активность -- активные формы кислорода (АФК) -- хемилюминесценция -- куры
Аннотация: Исследование влияния многократных антигенных стимуляций живыми вирусвакцинами на способность клеток цельной крови кур генерировать активные формы кислорода (АФК) методом люминол- и люцигенинзависимой хемилюминесценции выявило закономерное изменение кинетики респираторного взрыва и снижение индекса активации продукции первичных (O2-) и вторичных (H2O2, OH-, HClO-) АФК в ответ на антигенную стимуляцию in vitro, что свидетельствует о снижении неспецифической резистентности организма на фоне формирующегося специфического иммунитета.
The research of influence of the repeating antigenic stimulations of the hens by alive virus-vaccine on ability of whole blood cells of hens to generate active forms of oxygen (ROS) by method of luminol- and lucigenin depending chemiluminescence has revealed natural change of the kinetics of the respiratory explosion and decrease in an index of activation of production primary (O2-) and secondary (H2O2, OH-, HClO-) ROS in reply to antigenic stimulation in vitro with increase in number of immunizations. That testifies about decreasing in nonspecific resistance of an organism on a background of just forming specific immunity.
РИНЦ
Держатели документа:
ИВМ СО РАН
Институт прикладной биотехнологии и ветеринарной медицины ФГБОУ ВПО «Красноярский государственный аграрный университет»)
Международный научный центр исследований экстремальных состояний организма при Президиуме ФГБУ науки Красноярский научный центр СО РАН
Доп.точки доступа:
Макарская, Галина Владимировна; Makarskaya G.V.; Тарских, Светлана Вениаминовна; Tarskikh S.V.; Турицына, Евгения Геннадьевна; Turitsyna E.G.
| УДК |
Кл.слова (ненормированные):
иммунизация -- фагоцитоз -- функциональная активность -- активные формы кислорода (АФК) -- хемилюминесценция -- куры
Аннотация: Исследование влияния многократных антигенных стимуляций живыми вирусвакцинами на способность клеток цельной крови кур генерировать активные формы кислорода (АФК) методом люминол- и люцигенинзависимой хемилюминесценции выявило закономерное изменение кинетики респираторного взрыва и снижение индекса активации продукции первичных (O2-) и вторичных (H2O2, OH-, HClO-) АФК в ответ на антигенную стимуляцию in vitro, что свидетельствует о снижении неспецифической резистентности организма на фоне формирующегося специфического иммунитета.
The research of influence of the repeating antigenic stimulations of the hens by alive virus-vaccine on ability of whole blood cells of hens to generate active forms of oxygen (ROS) by method of luminol- and lucigenin depending chemiluminescence has revealed natural change of the kinetics of the respiratory explosion and decrease in an index of activation of production primary (O2-) and secondary (H2O2, OH-, HClO-) ROS in reply to antigenic stimulation in vitro with increase in number of immunizations. That testifies about decreasing in nonspecific resistance of an organism on a background of just forming specific immunity.
РИНЦ
Держатели документа:
ИВМ СО РАН
Институт прикладной биотехнологии и ветеринарной медицины ФГБОУ ВПО «Красноярский государственный аграрный университет»)
Международный научный центр исследований экстремальных состояний организма при Президиуме ФГБУ науки Красноярский научный центр СО РАН
Доп.точки доступа:
Макарская, Галина Владимировна; Makarskaya G.V.; Тарских, Светлана Вениаминовна; Tarskikh S.V.; Турицына, Евгения Геннадьевна; Turitsyna E.G.
Kinetics of formation of reactive oxygen species by blood cells when exposed to ultra-low doses of ionizing radiation
/ A. S. Fedotova [et al.] // IOP Conference Series: Earth and Environmental Science : Institute of Physics Publishing, 2019. - Vol. 315: International Scientific Conference on Agribusiness, Environmental Engineering and Biotechnologies, AGRITECH 2019 (20 June 2019 through 22 June 2019, ) Conference code: 152072, Is. 4. - Ст. 042017, DOI 10.1088/1755-1315/315/4/042017
. -
Кл.слова (ненормированные):
Biotechnology -- Cells -- Cytology -- Environmental technology -- Ionization of gases -- Ionizing radiation -- Kinetics -- Oxygen -- Chemiluminescent analysis -- Functional activities -- Hematological parameters -- Lactating cows -- Peripheral blood -- Phagocytic activity -- Primary radicals -- Reactive oxygen species -- Blood
Аннотация: The article contains the results of hematological, immunological and chemiluminescent analysis of the functional activity of peripheral blood cells of five-year-old lactating cows from the central regions of the Krasnoyarsk Territory (Siberia, Russia) with different radiation status, at which the radiation doses of animals were 0.02, 0.17 and 0.21 mSv per year. It was established that small doses of radiation at 0.17 mSv per year and 0.21 mSv per year affect hematological parameters, increase the phagocytic activity of blood leukocytes and change the kinetics of the formation of active oxygen forms by blood cells, which is manifested as an increase in the time of formation of the maximum kinetics of spontaneous and activated secondary radicals, reduction of the total production of secondary radicals in the antigenic activation of blood cells in vitro and an increase in the volume of spontaneously produced primary radicals. © 2019 IOP Publishing Ltd. All rights reserved.
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Держатели документа:
Krasnoyarsk State Agrarian University, 90 Mira ane., Krasnoyarsk, 660049, Russian Federation
Institute of Computational Modeling SB RAS, 50/44 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
ISC Research Center for Extreme States of the Body at the Presidium of the FIC KSC SB RAS, 50/12 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Доп.точки доступа:
Fedotova, A. S.; Turitsina, E. G.; Makarskaya, G. V.; Tarskikh, S. V.
Кл.слова (ненормированные):
Biotechnology -- Cells -- Cytology -- Environmental technology -- Ionization of gases -- Ionizing radiation -- Kinetics -- Oxygen -- Chemiluminescent analysis -- Functional activities -- Hematological parameters -- Lactating cows -- Peripheral blood -- Phagocytic activity -- Primary radicals -- Reactive oxygen species -- Blood
Аннотация: The article contains the results of hematological, immunological and chemiluminescent analysis of the functional activity of peripheral blood cells of five-year-old lactating cows from the central regions of the Krasnoyarsk Territory (Siberia, Russia) with different radiation status, at which the radiation doses of animals were 0.02, 0.17 and 0.21 mSv per year. It was established that small doses of radiation at 0.17 mSv per year and 0.21 mSv per year affect hematological parameters, increase the phagocytic activity of blood leukocytes and change the kinetics of the formation of active oxygen forms by blood cells, which is manifested as an increase in the time of formation of the maximum kinetics of spontaneous and activated secondary radicals, reduction of the total production of secondary radicals in the antigenic activation of blood cells in vitro and an increase in the volume of spontaneously produced primary radicals. © 2019 IOP Publishing Ltd. All rights reserved.
Scopus,
Смотреть статью
Держатели документа:
Krasnoyarsk State Agrarian University, 90 Mira ane., Krasnoyarsk, 660049, Russian Federation
Institute of Computational Modeling SB RAS, 50/44 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
ISC Research Center for Extreme States of the Body at the Presidium of the FIC KSC SB RAS, 50/12 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Доп.точки доступа:
Fedotova, A. S.; Turitsina, E. G.; Makarskaya, G. V.; Tarskikh, S. V.
An impact of low doses radiation on the kinetics of reactive oxygen species generation in sheep peripheral blood
/ A. S. Fedotova, G. V. Makarskaya, S. V. Tarskikh [et al.] // IOP Conference Series: Earth and Environmental Science : Institute of Physics Publishing, 2020. - Vol. 421: 2nd International Scientific Conference on Agribusiness, Environmental Engineering and Biotechnologies, AGRITECH-II 2019 (13 November 2019 through 14 November 2019, ) Conference code: 156846, Is. 5. - Ст. 052016, DOI 10.1088/1755-1315/421/5/052016
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Кл.слова (ненормированные):
Antigens -- Biotechnology -- Environmental technology -- Ionizing radiation -- Oxygen -- Petroleum reservoir evaluation -- Intensity levels -- Low dose -- Lucigenin -- Luminols -- Maximum intensities -- Peripheral blood -- Reactive oxygen species -- Blood
Аннотация: The work is devoted to measuring the impact of low doses of ionizing radiation on the kinetics of reactive oxygen species (ROS) generation in sheep peripheral blood. In the evaluation of the OAF production intensity level by the peripheral blood cells in the animals existing on the territories with different radiation tense by chemiluminescent method, it was established that having increased dose tense from 0,91 till 1.55 mGy/year, the amplitude of maximum intensity credibly increased, as well as the total amount of spontaneous and antigen activated primary lucigenin dependent ROS production and antigen activated secondary luminol dependent ROS with time decrease for the maximum achievement of the respiratory explosion. © Published under licence by IOP Publishing Ltd.
Scopus
Держатели документа:
Krasnoyarsk State Agrarian University, 90 Mira lane., Krasnoyarsk, 660049, Russian Federation
Institute of Computational Modelling, SB RAS, 50/44 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
ISC of Researches of Extreme Conditions of An Organism at the Presidium of the FIC KSC SB RAS, 50/12 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Доп.точки доступа:
Fedotova, A. S.; Makarskaya, G. V.; Tarskikh, S. V.; Turitcyna, E. G.; Kolesnikov, V. A.
Кл.слова (ненормированные):
Antigens -- Biotechnology -- Environmental technology -- Ionizing radiation -- Oxygen -- Petroleum reservoir evaluation -- Intensity levels -- Low dose -- Lucigenin -- Luminols -- Maximum intensities -- Peripheral blood -- Reactive oxygen species -- Blood
Аннотация: The work is devoted to measuring the impact of low doses of ionizing radiation on the kinetics of reactive oxygen species (ROS) generation in sheep peripheral blood. In the evaluation of the OAF production intensity level by the peripheral blood cells in the animals existing on the territories with different radiation tense by chemiluminescent method, it was established that having increased dose tense from 0,91 till 1.55 mGy/year, the amplitude of maximum intensity credibly increased, as well as the total amount of spontaneous and antigen activated primary lucigenin dependent ROS production and antigen activated secondary luminol dependent ROS with time decrease for the maximum achievement of the respiratory explosion. © Published under licence by IOP Publishing Ltd.
Scopus
Держатели документа:
Krasnoyarsk State Agrarian University, 90 Mira lane., Krasnoyarsk, 660049, Russian Federation
Institute of Computational Modelling, SB RAS, 50/44 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
ISC of Researches of Extreme Conditions of An Organism at the Presidium of the FIC KSC SB RAS, 50/12 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Доп.точки доступа:
Fedotova, A. S.; Makarskaya, G. V.; Tarskikh, S. V.; Turitcyna, E. G.; Kolesnikov, V. A.