[Text] : статья / G. V. Makarskaya, S. V. Tarskikh, E. G. Turitsyna // Russian Agricultural Sciences. - 2011. - Vol. 37, № 3. - p. 254-257, DOI 10.3103/S1068367411030128
. - ISSN 1068-3674
Полный текст
Держатели документа:
ИВМ СО РАН : 660036, Красноярск, Академгородок, 50, стр.44
Доп.точки доступа:
Tarskikh, S.V.; Turitsyna, E.G.; Макарская, Галина Владимировна
Труды сотрудников ИВМ СО РАН
w10=
Найдено документов в текущей БД: 30
Luminol-Lucigenin-Dependent Chemiluminescence of Chicken Whole-Blood Cells during Postnatal Ontogeny
Rectification effect of a radiation force
[Text] : статья / A.P. Kazantsev, I.V. Krasnov // Journal of the Optical Society of America B. - 1989. - Vol. 6, № 11. - p. 2140-2148DOI: 10.1364/JOSAB.6.002140
. -
Аннотация: A radiation-pressure force, changing only slightly within the wavelength of light (rectification effect), has been shown to arise in interfering fields. In a monochromatic field a rectified force (RF) has the scale of a spontaneous light-pressure force, and it is mainly a vortex one. In a bichromatic field the RF has the order of magnitude of the induced light-pressure force and does saturate in a strong field. The spatial RF structure can be either potential or rotational. The depth of the potential wells generated by the RF can exceed by several orders of magnitude the energy of the atom-field interaction, and it can reach 10 K and larger. A vortex periodic RF results either in regular rotating motion or in a random walk of atoms along the boundaries of elementary cells of the force field. Possible applications of the RF are discussed.
Держатели документа:
ИВМ СО РАН : 660036, Красноярск, Академгородок, 50, стр.44
Доп.точки доступа:
Krasnov, I.V.; Краснов, Игорь Васильевич
Аннотация: A radiation-pressure force, changing only slightly within the wavelength of light (rectification effect), has been shown to arise in interfering fields. In a monochromatic field a rectified force (RF) has the scale of a spontaneous light-pressure force, and it is mainly a vortex one. In a bichromatic field the RF has the order of magnitude of the induced light-pressure force and does saturate in a strong field. The spatial RF structure can be either potential or rotational. The depth of the potential wells generated by the RF can exceed by several orders of magnitude the energy of the atom-field interaction, and it can reach 10 K and larger. A vortex periodic RF results either in regular rotating motion or in a random walk of atoms along the boundaries of elementary cells of the force field. Possible applications of the RF are discussed.
Держатели документа:
ИВМ СО РАН : 660036, Красноярск, Академгородок, 50, стр.44
Доп.точки доступа:
Krasnov, I.V.; Краснов, Игорь Васильевич
Peculiarities of functional activity of the peripheral blood cells of fishes of the middle section of the krasnoyarsk reservoir in summer period
[Text] / G.V. Makarskaya, S.V. Tarskikh // Hydrobiological Journal. - 2012. - Vol. 48, Is. 1. - pp. 83-90, DOI 10.1615/HydrobJ.v48.i1.100
. - ISSN 0018-8166
Кл.слова (ненормированные):
Active oxygen forms -- Blood -- Chemiluminescence -- Fishes -- Functional activity -- Non-specific resistance -- Phagocytosis -- blood -- fish -- functional change -- metabolism -- monitoring -- oxygen -- phagotrophy -- quantitative analysis -- reservoir -- seasonal variation -- spawning -- summer -- water level -- Krasnoyarsk [Russian Federation] -- Russian Federation -- Pisces
Аннотация: Paper deals with results of monitoring of the quantitative and functional characteristics of the peripheral blood cells of different fish species of the middle section of the Krasnoyarsk reservoir over the years 2000-2009. Seasonal dynamics of the oxygen metabolism of the blood cells of different fishes was characterized by similar changes of the non-specific resistance in the spawning and post-spawning period under different level of the water filling of the reservoir. В© 2012 Begell House, Inc.
Scopus
Доп.точки доступа:
Makarskaya, G.V.; Макарская, Галина Владимировна; Tarskikh, S.V.
Кл.слова (ненормированные):
Active oxygen forms -- Blood -- Chemiluminescence -- Fishes -- Functional activity -- Non-specific resistance -- Phagocytosis -- blood -- fish -- functional change -- metabolism -- monitoring -- oxygen -- phagotrophy -- quantitative analysis -- reservoir -- seasonal variation -- spawning -- summer -- water level -- Krasnoyarsk [Russian Federation] -- Russian Federation -- Pisces
Аннотация: Paper deals with results of monitoring of the quantitative and functional characteristics of the peripheral blood cells of different fish species of the middle section of the Krasnoyarsk reservoir over the years 2000-2009. Seasonal dynamics of the oxygen metabolism of the blood cells of different fishes was characterized by similar changes of the non-specific resistance in the spawning and post-spawning period under different level of the water filling of the reservoir. В© 2012 Begell House, Inc.
Scopus
Доп.точки доступа:
Makarskaya, G.V.; Макарская, Галина Владимировна; Tarskikh, S.V.
Dynamical modeling of microRNA action on the protein translation process
[Text] / A.Zinovyev [et al.] // BMC Syst. Biol. - 2010. - Vol. 4. - Ст. 13, DOI 10.1186/1752-0509-4-13. - Cited References: 66. - We acknowledge support from Agence Nationale de la Recherche (project ANR-08-SYSC-003 CALAMAR) and from the Projet Incitatif Collaboratif "Bioinformatics and Biostatistics of Cancer" at Institut Curie. AZ and EB are members of the team "Systems Biology of Cancer" Equipe labellis'ee par la Ligue Nationale Contre le Cancer. This work was supported by the European Commission Sixth Framework Programme Integrated Project SIROCCO contract number LSHG-CT-2006-037900. We thank Vitaly Volpert and Laurence Calzone for inspiring and useful discussions.
. - ISSN 1752-0509
РУБ Mathematical & Computational Biology
Аннотация: Background: Protein translation is a multistep process which can be represented as a cascade of biochemical reactions (initiation, ribosome assembly, elongation, etc.), the rate of which can be regulated by small non-coding microRNAs through multiple mechanisms. It remains unclear what mechanisms of microRNA action are the most dominant: moreover, many experimental reports deliver controversial messages on what is the concrete mechanism actually observed in the experiment. Nissan and Parker have recently demonstrated that it might be impossible to distinguish alternative biological hypotheses using the steady state data on the rate of protein synthesis. For their analysis they used two simple kinetic models of protein translation. Results: In contrary to the study by Nissan and Parker, we show that dynamical data allow discriminating some of the mechanisms of microRNA action. We demonstrate this using the same models as developed by Nissan and Parker for the sake of comparison but the methods developed (asymptotology of biochemical networks) can be used for other models. We formulate a hypothesis that the effect of microRNA action is measurable and observable only if it affects the dominant system (generalization of the limiting step notion for complex networks) of the protein translation machinery. The dominant system can vary in different experimental conditions that can partially explain the existing controversy of some of the experimental data. Conclusions: Our analysis of the transient protein translation dynamics shows that it gives enough information to verify or reject a hypothesis about a particular molecular mechanism of microRNA action on protein translation. For multiscale systems only that action of microRNA is distinguishable which affects the parameters of dominant system (critical parameters), or changes the dominant system itself. Dominant systems generalize and further develop the old and very popular idea of limiting step. Algorithms for identifying dominant systems in multiscale kinetic models are straightforward but not trivial and depend only on the ordering of the model parameters but not on their concrete values. Asymptotic approach to kinetic models allows putting in order diverse experimental observations in complex situations when many alternative hypotheses co-exist.
Доп.точки доступа:
Zinovyev, A.; Morozova, N.; Nonne, N.; Barillot, E.; Harel-Bellan, A.; Gorban, A.N.; Горбань, Александр Николаевич
Рубрики:
MESSENGER-RNAS
CHEMICAL-KINETICS
HUMAN-CELLS
MAMMALIAN-CELLS
LET-7 MICRORNA
INITIATION
REPRESSION
INHIBITION
GENE
MANIFOLDS
MESSENGER-RNAS
CHEMICAL-KINETICS
HUMAN-CELLS
MAMMALIAN-CELLS
LET-7 MICRORNA
INITIATION
REPRESSION
INHIBITION
GENE
MANIFOLDS
Аннотация: Background: Protein translation is a multistep process which can be represented as a cascade of biochemical reactions (initiation, ribosome assembly, elongation, etc.), the rate of which can be regulated by small non-coding microRNAs through multiple mechanisms. It remains unclear what mechanisms of microRNA action are the most dominant: moreover, many experimental reports deliver controversial messages on what is the concrete mechanism actually observed in the experiment. Nissan and Parker have recently demonstrated that it might be impossible to distinguish alternative biological hypotheses using the steady state data on the rate of protein synthesis. For their analysis they used two simple kinetic models of protein translation. Results: In contrary to the study by Nissan and Parker, we show that dynamical data allow discriminating some of the mechanisms of microRNA action. We demonstrate this using the same models as developed by Nissan and Parker for the sake of comparison but the methods developed (asymptotology of biochemical networks) can be used for other models. We formulate a hypothesis that the effect of microRNA action is measurable and observable only if it affects the dominant system (generalization of the limiting step notion for complex networks) of the protein translation machinery. The dominant system can vary in different experimental conditions that can partially explain the existing controversy of some of the experimental data. Conclusions: Our analysis of the transient protein translation dynamics shows that it gives enough information to verify or reject a hypothesis about a particular molecular mechanism of microRNA action on protein translation. For multiscale systems only that action of microRNA is distinguishable which affects the parameters of dominant system (critical parameters), or changes the dominant system itself. Dominant systems generalize and further develop the old and very popular idea of limiting step. Algorithms for identifying dominant systems in multiscale kinetic models are straightforward but not trivial and depend only on the ordering of the model parameters but not on their concrete values. Asymptotic approach to kinetic models allows putting in order diverse experimental observations in complex situations when many alternative hypotheses co-exist.
Доп.точки доступа:
Zinovyev, A.; Morozova, N.; Nonne, N.; Barillot, E.; Harel-Bellan, A.; Gorban, A.N.; Горбань, Александр Николаевич
Energy method for mathematical modeling of heat transfer in 2-D flow
/ V. V. Denisenko // J. Sib. Fed. Univ. Math. Phys. - 2014. - Vol. 7, Is. 4. - P431-442
. - ISSN 1997-1397
Кл.слова (ненормированные):
Electrophoresis -- Elliptical equation -- Energy method -- Mathematical modeling -- Nonsymmetric operator
Аннотация: A multigrid finite element method for 2-D convection-heat transfer problem is proposed. The method is based on minimization of the energy functional. Effectiveness of the method is demonstrated by calculation of temperature distribution in a microchip that separates living cells from fluid stream by electrophoresis. © Siberian Federal University. All rights reserved.
Scopus,
Полный текст
Держатели документа:
Institute of Computational Modelling RAS SB, Academgorodok, Krasnoyarsk, Russian Federation
Institute of Mathematics and Computer Science, Siberian Federal University, Svobodny, 79, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Denisenko, V.V.; Денисенко, Валерий Васильевич
Кл.слова (ненормированные):
Electrophoresis -- Elliptical equation -- Energy method -- Mathematical modeling -- Nonsymmetric operator
Аннотация: A multigrid finite element method for 2-D convection-heat transfer problem is proposed. The method is based on minimization of the energy functional. Effectiveness of the method is demonstrated by calculation of temperature distribution in a microchip that separates living cells from fluid stream by electrophoresis. © Siberian Federal University. All rights reserved.
Scopus,
Полный текст
Держатели документа:
Institute of Computational Modelling RAS SB, Academgorodok, Krasnoyarsk, Russian Federation
Institute of Mathematics and Computer Science, Siberian Federal University, Svobodny, 79, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Denisenko, V.V.; Денисенко, Валерий Васильевич
577.29
Ф 94
Ф 94
Функционализированные аптамерами магнитные нанодиски для нанохирургии опухолей
[Текст] : статья / С. С. Замай [и др.] // Сибирское медицинское обозрение. - 2015. - № 6. - С. 48-54
. - ISSN 1819-9496
Перевод заглавия: Functionalized by the aptamers magnetic nanodiscs for nanosurgery of the tumors
Кл.слова (ненормированные):
нанохирургия -- Nanosurgery -- nickel magnetic nanodiscs -- Aptamers -- Ehrlich ascites carcinoma -- никелевые магнитные нанодиски -- аптамеры -- асцитная карцинома Эрлиха
Аннотация: Цель исследования. Определение перспектив использования функционализированных ДНК-аптамерами магнитных никелевых нанодисков с золотым покрытием для адресной клеточной хирургии онкологических заболеваний. Матери алы и методы. В качестве модели опухоли была использована асцитная карцинома Эрлиха. Теоретически и экспериментально исследованы структуры магнитного поля пермаллоевых и кобальтовых дисков Au-Fe(20)Ni(80)-Au и Au-Co-Au. Результаты. Выполнены оценки механического воздействия нанодисков на клеточную мембрану в переменном магнитном поле. Определены оптимальные состав, геометрия и структура остаточной намагниченности нанодисков. Экспериментально in vitro и in vivo для асцитной карциномы Эрлиха показана возможность использования функционализированных ДНК-аптамерами трехслойных Au-Ni-Au нанодисков с дипольной структурой остаточной намагниченности для адресного разрушения клеток-мишеней. 3аключе-ие. На основании теоретических расчетов и экспериментальных данных сделано заключение о том, что нанодиски Au-Ni-Au, обладающие магнитными свойствами, могут быть использованы для разработки новых методов и препаратов для малоинвазивной клеточной нанохирургии, которая позволяет адресно и дозировано уничтожать только клетки опухоли, в том числе, и метастазы.
The aim of the research. Determination of the prospects of application the functionalized by DNA-aptamers magnetic nickel nanodiscs with gold coating for targeted cell cancer surgery. Materials and methods. As tumor model was used Ehrlich ascites carcinoma. Theoretically and experimentally were investigated the structures of the magnetic field of permalloy and cobalt disks Au-Fe (20) Ni (80) -Au and Au-Co-Au. Results. It were executed the estimation of the mechanical impact of nanodiscs to the cell membrane in an alternating magnetic field. It was determined the optimum composition, geometry and structure of the residual magnetization of nanodiscs. Experimentally in vitro and in vivo for Ehrlich ascites carcinoma was showed the use of functionalized DNA-aptamers three layer Au-Ni-Au nanodisks with dipole structure of the residual magnetization for address destruction of the target cells. Conclusion. On the basis of theoretical calculations and experimental data, it was concluded that nanodiscs Au-Ni-Au, with magnetic properties, can be used to develop new methods and products for minimally invasive cellular nanosurgery that allows targeted and dosed destroy only tumor cells, including metastasis.
РИНЦ
Держатели документа:
ГАОУ ВПО Сибирский федеральный университет
ГБОУ ВПО Красноярский государственный медицинский университет имени проф. В. Ф. Войно-Ясенецкого Министерства здравоохранения РФ
ГБОУ ВПО Красноярский государственный педагогический университет им. В. П. Астафьева Министерства образования и науки РФ
Институт вычислительного моделирования СО РАН
Красноярский научный центр СО РАН
Доп.точки доступа:
Замай, Сергей Сергеевич; Zamay Sergey Sergeevich; Прокопенко, Владимир Семенович; Prokopenko Vladimir Semenovich; Замай, Анна Сергеевна; Zamay Anna Sergeevna; Денисенко, Валерий Васильевич; Denisenko V.V.; Ким, Петр Дементьевич; Kim Petr Dementievich; Орлов, Виталий Александрович; Orlov Vitaly Alerksandrovich; Замай, Галина Сергеевна; Zamay Galina Sergeevna; Иванченко, Татьяна Ивановна; Ivanchenko Tatiana Ivanovna; Замай, Татьяна Николаевна; Zamay Tatiana Nikolaevna
Перевод заглавия: Functionalized by the aptamers magnetic nanodiscs for nanosurgery of the tumors
| УДК |
Кл.слова (ненормированные):
нанохирургия -- Nanosurgery -- nickel magnetic nanodiscs -- Aptamers -- Ehrlich ascites carcinoma -- никелевые магнитные нанодиски -- аптамеры -- асцитная карцинома Эрлиха
Аннотация: Цель исследования. Определение перспектив использования функционализированных ДНК-аптамерами магнитных никелевых нанодисков с золотым покрытием для адресной клеточной хирургии онкологических заболеваний. Матери алы и методы. В качестве модели опухоли была использована асцитная карцинома Эрлиха. Теоретически и экспериментально исследованы структуры магнитного поля пермаллоевых и кобальтовых дисков Au-Fe(20)Ni(80)-Au и Au-Co-Au. Результаты. Выполнены оценки механического воздействия нанодисков на клеточную мембрану в переменном магнитном поле. Определены оптимальные состав, геометрия и структура остаточной намагниченности нанодисков. Экспериментально in vitro и in vivo для асцитной карциномы Эрлиха показана возможность использования функционализированных ДНК-аптамерами трехслойных Au-Ni-Au нанодисков с дипольной структурой остаточной намагниченности для адресного разрушения клеток-мишеней. 3аключе-ие. На основании теоретических расчетов и экспериментальных данных сделано заключение о том, что нанодиски Au-Ni-Au, обладающие магнитными свойствами, могут быть использованы для разработки новых методов и препаратов для малоинвазивной клеточной нанохирургии, которая позволяет адресно и дозировано уничтожать только клетки опухоли, в том числе, и метастазы.
The aim of the research. Determination of the prospects of application the functionalized by DNA-aptamers magnetic nickel nanodiscs with gold coating for targeted cell cancer surgery. Materials and methods. As tumor model was used Ehrlich ascites carcinoma. Theoretically and experimentally were investigated the structures of the magnetic field of permalloy and cobalt disks Au-Fe (20) Ni (80) -Au and Au-Co-Au. Results. It were executed the estimation of the mechanical impact of nanodiscs to the cell membrane in an alternating magnetic field. It was determined the optimum composition, geometry and structure of the residual magnetization of nanodiscs. Experimentally in vitro and in vivo for Ehrlich ascites carcinoma was showed the use of functionalized DNA-aptamers three layer Au-Ni-Au nanodisks with dipole structure of the residual magnetization for address destruction of the target cells. Conclusion. On the basis of theoretical calculations and experimental data, it was concluded that nanodiscs Au-Ni-Au, with magnetic properties, can be used to develop new methods and products for minimally invasive cellular nanosurgery that allows targeted and dosed destroy only tumor cells, including metastasis.
РИНЦ
Держатели документа:
ГАОУ ВПО Сибирский федеральный университет
ГБОУ ВПО Красноярский государственный медицинский университет имени проф. В. Ф. Войно-Ясенецкого Министерства здравоохранения РФ
ГБОУ ВПО Красноярский государственный педагогический университет им. В. П. Астафьева Министерства образования и науки РФ
Институт вычислительного моделирования СО РАН
Красноярский научный центр СО РАН
Доп.точки доступа:
Замай, Сергей Сергеевич; Zamay Sergey Sergeevich; Прокопенко, Владимир Семенович; Prokopenko Vladimir Semenovich; Замай, Анна Сергеевна; Zamay Anna Sergeevna; Денисенко, Валерий Васильевич; Denisenko V.V.; Ким, Петр Дементьевич; Kim Petr Dementievich; Орлов, Виталий Александрович; Orlov Vitaly Alerksandrovich; Замай, Галина Сергеевна; Zamay Galina Sergeevna; Иванченко, Татьяна Ивановна; Ivanchenko Tatiana Ivanovna; Замай, Татьяна Николаевна; Zamay Tatiana Nikolaevna
Динамика функциональной активности клеток неспецифической резистентности в процессе онтогенеза у рыб Красноярского водохранилища
[Текст] : статья / Г. В. Макарская, С. В. Тарских // Проблемы патологии, иммунологии и охраны здоровья рыб и других гидробионтов. - 2015. - С. 190-198
. - ISBN 978-5-906682-37-6
Перевод заглавия: Dynamics of functional activity of nonspecific resistency cells of fishs of Krasnoyarsk reservoir during ontogenesis
Аннотация: The age-specific dynamics of functional activity of fish blood cells, estimated by kinetics of ROS generation by antigene-activated immunocompetent cells in system of whole blood at all surveyed kinds of the fishes is characterized. The intensity and volume of ROS generation of blood cells are changing with increase in age and the maximum of reaction is displaced to more later time, that probably testifies about decreasing of activity of pro- and antioxydant enzymes of cells and factors of a cellular environment. The first 3 years of a life at the perch, 6 years at the roach and 8 years at the bream are characterized increase in activity of production ROS, thus distribution of volume of production ROS directly connected with phagocytosis, is specific to each kind and changes in process of aging of individuals.
РИНЦ,
Источник статьи
Держатели документа:
2Международный научный центр исследований экстремальных состояний организма при Президиуме Красноярского научного центра СО РАН
Институт вычислительного моделирования СО РАН
Доп.точки доступа:
Тарских, С.В.; Makarskaya G.V.; IV Международная конференция "Проблемы патологии, иммунологии и охраны здоровья рыб и других гидробионтов" (2015 ; 24.09 - 27.09 ; Борок)
Перевод заглавия: Dynamics of functional activity of nonspecific resistency cells of fishs of Krasnoyarsk reservoir during ontogenesis
Аннотация: The age-specific dynamics of functional activity of fish blood cells, estimated by kinetics of ROS generation by antigene-activated immunocompetent cells in system of whole blood at all surveyed kinds of the fishes is characterized. The intensity and volume of ROS generation of blood cells are changing with increase in age and the maximum of reaction is displaced to more later time, that probably testifies about decreasing of activity of pro- and antioxydant enzymes of cells and factors of a cellular environment. The first 3 years of a life at the perch, 6 years at the roach and 8 years at the bream are characterized increase in activity of production ROS, thus distribution of volume of production ROS directly connected with phagocytosis, is specific to each kind and changes in process of aging of individuals.
РИНЦ,
Источник статьи
Держатели документа:
2Международный научный центр исследований экстремальных состояний организма при Президиуме Красноярского научного центра СО РАН
Институт вычислительного моделирования СО РАН
Доп.точки доступа:
Тарских, С.В.; Makarskaya G.V.; IV Международная конференция "Проблемы патологии, иммунологии и охраны здоровья рыб и других гидробионтов" (2015 ; 24.09 - 27.09 ; Борок)
Возрастные изменения функциональной активности клеток органов cиcтемы иммуногенеза цыплят
[Текст] : статья / Г. В. Макарская, С. В. Тарских, Е. Г. Турицына // Наука и образование : материалы XIV международной научно-практической конференции. - Красноярск : Красноярский государственный аграрный университет, 2015. - Ч. II. - С. 251-256
Аннотация: The natural age dynamics of the volume of ROS generation and an index of activation of cells was detected by the chemiluminescent analysis of functional activity of cells of peripheral blood and immunocompetent bodies of chickens of early age.
РИНЦ,
Источник статьи
Держатели документа:
Институт вычислительного моделирования Сибирского отделения Российской академии наук
Красноярский государственный аграрный университет
Международный научный центр исследований экстремальных состояний организма при Президиуме Федерального государственного бюджетного учреждения науки Красноярский научный центр СО РАН
Доп.точки доступа:
Тарских, С.В.; Турицына, Е.Г.; Makarskaya G.V.; Наука и образование: опыт, проблемы, перспективы развития (2015 ; 22.04 - 23.04 ; Красноярск)
Аннотация: The natural age dynamics of the volume of ROS generation and an index of activation of cells was detected by the chemiluminescent analysis of functional activity of cells of peripheral blood and immunocompetent bodies of chickens of early age.
РИНЦ,
Источник статьи
Держатели документа:
Институт вычислительного моделирования Сибирского отделения Российской академии наук
Красноярский государственный аграрный университет
Международный научный центр исследований экстремальных состояний организма при Президиуме Федерального государственного бюджетного учреждения науки Красноярский научный центр СО РАН
Доп.точки доступа:
Тарских, С.В.; Турицына, Е.Г.; Makarskaya G.V.; Наука и образование: опыт, проблемы, перспективы развития (2015 ; 22.04 - 23.04 ; Красноярск)
Optimization of photothermal methods for laser hyperthermia of malignant cells using bioconjugates of gold nanoparticles
/ V. S. Gerasimov [et al.] // Colloid J. - 2016. - Vol. 78, Is. 4. - P435-442, DOI 10.1134/S1061933X16040050
. - ISSN 1061-933X
Кл.слова (ненормированные):
Biomolecules -- Cell membranes -- Cells -- Continuous wave lasers -- Cytology -- Fiber optic sensors -- Gold -- Laser radiation -- Metal nanoparticles -- Nanoparticles -- Oligonucleotides -- Bioconjugates -- Cell surfaces -- Cellular membranes -- DNA aptamers -- Gold Nanoparticles -- Malignant cells -- Photothermal methods -- Pulsed lasers
Аннотация: Selective action of laser radiation on membranes of malignant cells has been studied in different regimes using conjugates of gold nanoparticles with oligonucleotides by the example of DNA aptamers. Under the conditions of a contact between a bioconjugate and a cell surface and the development of substantial and rapidly relaxing temperature gradients near a nanoparticle, the membranes of malignant cells alone are efficiently damaged due to the local hyperthermia of a cellular membrane. It has been shown that employment of pulsed instead of continuous wave laser radiation provides the localization of the damaging action, which does not involve healthy cells. © 2016, Pleiades Publishing, Ltd.
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Держатели документа:
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, Russian Federation
Kirenskii Institute of Physics, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/38, Krasnoyarsk, Russian Federation
Reshetnev State Siberian State Aerospace University, pr. Gazety “Krasnoyarskii rabochii” 31, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Gerasimov, V. S.; Ershov, A. E.; Karpov, S. V.; Polyutov, S. P.; Semina, P. N.
Кл.слова (ненормированные):
Biomolecules -- Cell membranes -- Cells -- Continuous wave lasers -- Cytology -- Fiber optic sensors -- Gold -- Laser radiation -- Metal nanoparticles -- Nanoparticles -- Oligonucleotides -- Bioconjugates -- Cell surfaces -- Cellular membranes -- DNA aptamers -- Gold Nanoparticles -- Malignant cells -- Photothermal methods -- Pulsed lasers
Аннотация: Selective action of laser radiation on membranes of malignant cells has been studied in different regimes using conjugates of gold nanoparticles with oligonucleotides by the example of DNA aptamers. Under the conditions of a contact between a bioconjugate and a cell surface and the development of substantial and rapidly relaxing temperature gradients near a nanoparticle, the membranes of malignant cells alone are efficiently damaged due to the local hyperthermia of a cellular membrane. It has been shown that employment of pulsed instead of continuous wave laser radiation provides the localization of the damaging action, which does not involve healthy cells. © 2016, Pleiades Publishing, Ltd.
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Держатели документа:
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, Russian Federation
Kirenskii Institute of Physics, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/38, Krasnoyarsk, Russian Federation
Reshetnev State Siberian State Aerospace University, pr. Gazety “Krasnoyarskii rabochii” 31, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Gerasimov, V. S.; Ershov, A. E.; Karpov, S. V.; Polyutov, S. P.; Semina, P. N.
Ratio between living and dead cells and the size structure of the Yenisei River phytoplankton downstream of the Krasnoyarsk Hydroelectric Power Station
/ Y. A. Ponomareva, E. A. Ivanova // Contemp. Probl. Ecol. - 2016. - Vol. 9, Is. 5. - P582-589, DOI 10.1134/S1995425516050115
. - ISSN 1995-4255
Кл.слова (ненормированные):
cell size -- downstream of dam -- phytoplankton -- ratio between living and dead cells -- Yenisei River -- algae
Аннотация: Based on a daily examination of phytoplankton in the Yenisei River downstream of the Krasnoyarsk Hydroelectric Power Station (HPS) within a 4-year period, the ratio between living and dead cells is estimated and the size fractions of phytoplankton are described. It is found that, despite the certain negative effects of passing through the turbine blades of the high-head dam, high current speed, and influence of water discharges from the HPS, living algae cells dominate over dead ones in the water column of the studied reach of the Yenisei River during almost the entire year, except for several dates in late autumn and winter. It is shown that microphytoplankton (20–64 ?m in size) and nanophytoplankton (2–20 ?m), which make up 83% of the total algae count, pass through the turbine blades of the HPS and mostly remain undamaged, with the fraction of living cells varying from 21% in the winter period to 96% in the spring–summer period. © 2016, Pleiades Publishing, Ltd.
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Держатели документа:
Siberian Federal University, pr. Svobodny 79, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Ponomareva, Y. A.; Ivanova, E. A.
Кл.слова (ненормированные):
cell size -- downstream of dam -- phytoplankton -- ratio between living and dead cells -- Yenisei River -- algae
Аннотация: Based on a daily examination of phytoplankton in the Yenisei River downstream of the Krasnoyarsk Hydroelectric Power Station (HPS) within a 4-year period, the ratio between living and dead cells is estimated and the size fractions of phytoplankton are described. It is found that, despite the certain negative effects of passing through the turbine blades of the high-head dam, high current speed, and influence of water discharges from the HPS, living algae cells dominate over dead ones in the water column of the studied reach of the Yenisei River during almost the entire year, except for several dates in late autumn and winter. It is shown that microphytoplankton (20–64 ?m in size) and nanophytoplankton (2–20 ?m), which make up 83% of the total algae count, pass through the turbine blades of the HPS and mostly remain undamaged, with the fraction of living cells varying from 21% in the winter period to 96% in the spring–summer period. © 2016, Pleiades Publishing, Ltd.
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Держатели документа:
Siberian Federal University, pr. Svobodny 79, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Ponomareva, Y. A.; Ivanova, E. A.
Microconvection in vertical channel at given heat flux
/ V. B. Bekezhanova, I. A. Shefer // J. Phys. Conf. Ser. - 2016. - Vol. 754, Is. 2, DOI 10.1088/1742-6596/754/2/022001
. - ISSN 1742-6588
Кл.слова (ненормированные):
Fluid dynamics -- Heat conduction -- Heat transfer -- Hydrodynamics -- Thermal load -- Conducting liquid -- Disturbance waves -- Polygonal structures -- Problem parameters -- Spatial characteristics -- Thermal disturbance -- Two-dimensional flow -- Vertical channels -- Heat flux
Аннотация: A problem on stability of the viscous heat-conducting liquid flow in the vertical channel at given heat flux on the permeable solid walls is studied. The two-dimensional flow is described by an exact invariant solution of the microconvection equations. The investigation of the exact solution allows one to find out the extent of influence of the thermal load, gravity and the system geometry on the flow structure. Stability of the solution is investigated in the framework of the linear theory. The spectrum of the spatial characteristic perturbations is analyzed in the space of problem parameters. Typical forms of the hydrodynamic and thermal disturbances are presented and dependence of characteristics of the arising structures on the thermal load and gravity is established. Convective cells, hydrothermal rolls and polygonal structures can appear in the channel. By weak gravity the hydrothermal rolls are not formed. Changing heat flux and disturbance wave length lead to deformation of the cells and complication of the spatial form of the structures. © Published under licence by IOP Publishing Ltd.
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Держатели документа:
Institute of Computational Modeling, SB, RAS, 50/44 Krasnoyarsk, Akademgorodok, Russian Federation
Institute of Mathematics and Computer Sciences, Siberian Federal University, Svobodny, 79, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Bekezhanova, V. B.; Shefer, I. A.
Кл.слова (ненормированные):
Fluid dynamics -- Heat conduction -- Heat transfer -- Hydrodynamics -- Thermal load -- Conducting liquid -- Disturbance waves -- Polygonal structures -- Problem parameters -- Spatial characteristics -- Thermal disturbance -- Two-dimensional flow -- Vertical channels -- Heat flux
Аннотация: A problem on stability of the viscous heat-conducting liquid flow in the vertical channel at given heat flux on the permeable solid walls is studied. The two-dimensional flow is described by an exact invariant solution of the microconvection equations. The investigation of the exact solution allows one to find out the extent of influence of the thermal load, gravity and the system geometry on the flow structure. Stability of the solution is investigated in the framework of the linear theory. The spectrum of the spatial characteristic perturbations is analyzed in the space of problem parameters. Typical forms of the hydrodynamic and thermal disturbances are presented and dependence of characteristics of the arising structures on the thermal load and gravity is established. Convective cells, hydrothermal rolls and polygonal structures can appear in the channel. By weak gravity the hydrothermal rolls are not formed. Changing heat flux and disturbance wave length lead to deformation of the cells and complication of the spatial form of the structures. © Published under licence by IOP Publishing Ltd.
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Держатели документа:
Institute of Computational Modeling, SB, RAS, 50/44 Krasnoyarsk, Akademgorodok, Russian Federation
Institute of Mathematics and Computer Sciences, Siberian Federal University, Svobodny, 79, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Bekezhanova, V. B.; Shefer, I. A.
Mathematical modeling of the impact produced by magnetic disks on living cells
/ V. V. Denisenko, V. M. Sadovskii, S. S. Zamay // J. Sib. Fed. Univ. Math. Phys. - 2016. - Vol. 9, Is. 4. - P432-442, DOI 10.17516/1997-1397-2016-9-4-432-442
. - ISSN 1997-1397
Кл.слова (ненормированные):
Elastic membrane -- Elliptic boundary value problem -- Living cell -- Magnetic polarizability
Аннотация: An analytical solution of the problem on elastic deformation of a membrane allows analyzing deformation of typical living cells under the influence of magnetic disks attached to the cells. Based on the numerical solution of two-dimensional elliptic boundary value problems, the magnetic polarizabilities of the disks are obtained as the functions of magnetic permeability of the disk substance. It is shown that typical thin disks made of iron, nickel and cobalt in the mode far from saturation are magnetized substantially the same as a disk with infinite magnetic permeability. Though the solved problems are stationary, the results are also usable in the analysis of quasi-stationary processes such as low-frequency variation of external magnetic field. © Siberian Federal University. All rights reserved.
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Держатели документа:
Institute of Computational Modeling SB RAS, Akademgorodok, 50/44, Krasnoyarsk, Russian Federation
Institute of Mathematics and Computer Science, Siberian Federal University, Svobodny, 79, Krasnoyarsk, Russian Federation
Krasnoyarsk Scientific Center SB RAS, Akademgorodok, 50, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Denisenko, V. V.; Sadovskii, V. M.; Zamay, S. S.
Кл.слова (ненормированные):
Elastic membrane -- Elliptic boundary value problem -- Living cell -- Magnetic polarizability
Аннотация: An analytical solution of the problem on elastic deformation of a membrane allows analyzing deformation of typical living cells under the influence of magnetic disks attached to the cells. Based on the numerical solution of two-dimensional elliptic boundary value problems, the magnetic polarizabilities of the disks are obtained as the functions of magnetic permeability of the disk substance. It is shown that typical thin disks made of iron, nickel and cobalt in the mode far from saturation are magnetized substantially the same as a disk with infinite magnetic permeability. Though the solved problems are stationary, the results are also usable in the analysis of quasi-stationary processes such as low-frequency variation of external magnetic field. © Siberian Federal University. All rights reserved.
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Держатели документа:
Institute of Computational Modeling SB RAS, Akademgorodok, 50/44, Krasnoyarsk, Russian Federation
Institute of Mathematics and Computer Science, Siberian Federal University, Svobodny, 79, Krasnoyarsk, Russian Federation
Krasnoyarsk Scientific Center SB RAS, Akademgorodok, 50, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Denisenko, V. V.; Sadovskii, V. M.; Zamay, S. S.
517.95+537.63+57.04
M39
M39
Mathematical Modeling of the Impact Produced by Magnetic Disks on Living Cells
: статья / Valery V. Denisenko, Vladimir M. Sadovskii, Sergey S. Zamay // Журнал Сибирского федерального университета. Серия: Математика и физика. - 2016. - Т. 9, № 4. - P432-442, DOI 10.17516/1997-1397-2016-9-4-432-442
. - ISSN 1997-1397
Перевод заглавия: Математическое моделирование воздействия магнитных дисков на живые клетки
Кл.слова (ненормированные):
ellipticboundary valueproblem -- magneticpolarizability -- elastic membrane -- livingcell -- эллиптическая краевая задача -- магнитная поляризуемость -- упругая мембрана -- живая клетка
Аннотация: An analytical solutionoftheproblemon elastic deformationofa membraneallows analyzing deformation of typical living cells under the in?uence of magnetic disks attached to the cells. Based on the numerical solution of two-dimensional ellipticboundary value problems, the magneticpolarizabilities of the disks are obtained as the functions of magneticpermeability of the disk substance. It is shown that typical thin disks made of iron, nickel and cobalt in the mode far from saturation are magnetized substantially the sameasadiskwith in?nite magneticpermeability. Thoughthe solvedproblemsare stationary,theresults are also usable in the analysis of quasi-stationary processes such as low-frequency variation of external magnetic ?eld.
Построено аналитическое решение задачи о деформации упругой мембраны, которое позволяет анализировать деформации типичных живых клеток под воздействием прикрепленных к клеткам магнитных дисков. На основе численного решения двумерных эллиптических краевых задач получены зависимости магнитных поляризуемостей дисков от магнитной поницаемости их вещества. Показано, что типичные тонкие диски, изготовленные из железа, никеля, кобальта, в режимах, далеких от насыщения, намагничиваются практически так же, как при бесконечной магнитной проницаемости. В работе решены стационарные задачи, однако полученные результаты могут быть использованы и при анализе квазистационарных процессов, происходящих, например, при изменении внешнего магнитного поля с небольшой частотой.
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Держатели документа:
Institute of Computational Modeling SB RAS
Institute of Mathematics and Computer Science SiberianFederal University Svobodny
Krasnoyarsk Scienti?c Center SB RAS
Доп.точки доступа:
Sadovskii, V.M.; Садовский, Владимир Михайлович; Zamay, Sergey S.; Замай Сергей С.; Денисенко, Валерий Васильевич
Перевод заглавия: Математическое моделирование воздействия магнитных дисков на живые клетки
| УДК |
Кл.слова (ненормированные):
ellipticboundary valueproblem -- magneticpolarizability -- elastic membrane -- livingcell -- эллиптическая краевая задача -- магнитная поляризуемость -- упругая мембрана -- живая клетка
Аннотация: An analytical solutionoftheproblemon elastic deformationofa membraneallows analyzing deformation of typical living cells under the in?uence of magnetic disks attached to the cells. Based on the numerical solution of two-dimensional ellipticboundary value problems, the magneticpolarizabilities of the disks are obtained as the functions of magneticpermeability of the disk substance. It is shown that typical thin disks made of iron, nickel and cobalt in the mode far from saturation are magnetized substantially the sameasadiskwith in?nite magneticpermeability. Thoughthe solvedproblemsare stationary,theresults are also usable in the analysis of quasi-stationary processes such as low-frequency variation of external magnetic ?eld.
Построено аналитическое решение задачи о деформации упругой мембраны, которое позволяет анализировать деформации типичных живых клеток под воздействием прикрепленных к клеткам магнитных дисков. На основе численного решения двумерных эллиптических краевых задач получены зависимости магнитных поляризуемостей дисков от магнитной поницаемости их вещества. Показано, что типичные тонкие диски, изготовленные из железа, никеля, кобальта, в режимах, далеких от насыщения, намагничиваются практически так же, как при бесконечной магнитной проницаемости. В работе решены стационарные задачи, однако полученные результаты могут быть использованы и при анализе квазистационарных процессов, происходящих, например, при изменении внешнего магнитного поля с небольшой частотой.
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Держатели документа:
Institute of Computational Modeling SB RAS
Institute of Mathematics and Computer Science SiberianFederal University Svobodny
Krasnoyarsk Scienti?c Center SB RAS
Доп.точки доступа:
Sadovskii, V.M.; Садовский, Владимир Михайлович; Zamay, Sergey S.; Замай Сергей С.; Денисенко, Валерий Васильевич
Noninvasive Microsurgery Using Aptamer-Functionalized Magnetic Microdisks for Tumor Cell Eradication
/ T. N. Zamay [et al.] // Nucleic Acid Therape. - 2017. - Vol. 27, Is. 2. - P105-114, DOI 10.1089/nat.2016.0634
. - ISSN 2159-3337
Кл.слова (ненормированные):
aptamer -- magnetic microdisks -- magnetodynamic therapy -- tumor eradication
Аннотация: Magnetomechanical cell disruption using nano- and microsized structures is a promising biomedical technology used for noninvasive elimination of diseased cells. It applies alternating magnetic field (AMF) for ferromagnetic microdisks making them oscillate and causing cell membrane disruption with cell death followed by apoptosis. In this study, we functionalized the magnetic microdisks with cell-binding DNA aptamers and guided the microdisks to recognize cancerous cells in a mouse tumor in vivo. Only 10 min of the treatment with a 100 Hz AMF was enough to eliminate cancer cells from a malignant tumor. Our results demonstrate a good perspective of using aptamer-modified magnetic microdisks for noninvasive microsurgery for tumors. © Mary Ann Liebert, Inc. 2017.
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Держатели документа:
Laboratory of Biomolecular and Medical Technologies, Krasnoyarsk State Medical University, 1, P. Zheleznyaka, Krasnoyarsk, Russian Federation
Siberian Federal University, Krasnoyarsk, Russian Federation
Krasnoyarsk Research Center, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Institute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
Institute of Physics, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Krasnoyarsk State Pedagogical University, Krasnoyarsk, Russian Federation
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada
Доп.точки доступа:
Zamay, T. N.; Zamay, G. S.; Belyanina, I. V.; Zamay, S. S.; Denisenko, V.V.; Денисенко, Валерий Васильевич; Kolovskaya, O. S.; Ivanchenko, T. I.; Grigorieva, V. L.; Garanzha, I. V.; Veprintsev, D. V.; Glazyrin, Y. E.; Shabanov, A. V.; Prinz, V. Y.; Seleznev, V. A.; Sokolov, A. E.; Prokopenko, V. S.; Kim, P. D.; Gargaun, A.; Berezovski, M. V.; Zamay, A. S.
Кл.слова (ненормированные):
aptamer -- magnetic microdisks -- magnetodynamic therapy -- tumor eradication
Аннотация: Magnetomechanical cell disruption using nano- and microsized structures is a promising biomedical technology used for noninvasive elimination of diseased cells. It applies alternating magnetic field (AMF) for ferromagnetic microdisks making them oscillate and causing cell membrane disruption with cell death followed by apoptosis. In this study, we functionalized the magnetic microdisks with cell-binding DNA aptamers and guided the microdisks to recognize cancerous cells in a mouse tumor in vivo. Only 10 min of the treatment with a 100 Hz AMF was enough to eliminate cancer cells from a malignant tumor. Our results demonstrate a good perspective of using aptamer-modified magnetic microdisks for noninvasive microsurgery for tumors. © Mary Ann Liebert, Inc. 2017.
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Держатели документа:
Laboratory of Biomolecular and Medical Technologies, Krasnoyarsk State Medical University, 1, P. Zheleznyaka, Krasnoyarsk, Russian Federation
Siberian Federal University, Krasnoyarsk, Russian Federation
Krasnoyarsk Research Center, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Institute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
Institute of Physics, Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Krasnoyarsk State Pedagogical University, Krasnoyarsk, Russian Federation
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada
Доп.точки доступа:
Zamay, T. N.; Zamay, G. S.; Belyanina, I. V.; Zamay, S. S.; Denisenko, V.V.; Денисенко, Валерий Васильевич; Kolovskaya, O. S.; Ivanchenko, T. I.; Grigorieva, V. L.; Garanzha, I. V.; Veprintsev, D. V.; Glazyrin, Y. E.; Shabanov, A. V.; Prinz, V. Y.; Seleznev, V. A.; Sokolov, A. E.; Prokopenko, V. S.; Kim, P. D.; Gargaun, A.; Berezovski, M. V.; Zamay, A. S.
Secret life of tiny blood vessels: Lactate, scaffold and beyond
/ V. Salmin [et al.] // (26 April 2017 through 28 April 2017 : Springer Verlag, 2017. - Vol. 10208 LNCS. - P591-601, DOI 10.1007/978-3-319-56148-6_53
. -
Кл.слова (ненормированные):
Angiogenesis in vitro -- Brain microvessel endothelial cells -- Form factor -- Fractal dimension -- Gelatin scaffold -- Bioinformatics -- Biomedical engineering -- Blood vessels -- Brain -- Cells -- Cytology -- Endothelial cells -- Fractal dimension -- Fractals -- Angiogenesis -- Bio-scaffolds -- Form factors -- In-vitro -- Microenvironments -- Microvessel -- Microvessels -- Primary culture -- Scaffolds (biology)
Аннотация: We studied the model of cerebral angiogenesis in vitro using lactate-releasing gelatin bioscaffolds and primary culture of brain endothelial cells. We found that development of microvessels from actively proliferating rat brain microvessels endothelial cells was greatly modified by the presence of lactate at the surface of the scaffold with different lactate-releasing ability. Fractal dimension of newly-established vessel loops allows precise characterizing the local microenvironment supporting cell growth on various types of gelatin scaffolds. © Springer International Publishing AG 2017.
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Держатели документа:
Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Salmin, V.; Morgun, A.; Khilazheva, E.; Pisareva, N.; Boitsova, E.; Lavrentiev, P.; Sadovsky, M.G.; Садовский, Михаил Георгиевич; Salmina, A.
Кл.слова (ненормированные):
Angiogenesis in vitro -- Brain microvessel endothelial cells -- Form factor -- Fractal dimension -- Gelatin scaffold -- Bioinformatics -- Biomedical engineering -- Blood vessels -- Brain -- Cells -- Cytology -- Endothelial cells -- Fractal dimension -- Fractals -- Angiogenesis -- Bio-scaffolds -- Form factors -- In-vitro -- Microenvironments -- Microvessel -- Microvessels -- Primary culture -- Scaffolds (biology)
Аннотация: We studied the model of cerebral angiogenesis in vitro using lactate-releasing gelatin bioscaffolds and primary culture of brain endothelial cells. We found that development of microvessels from actively proliferating rat brain microvessels endothelial cells was greatly modified by the presence of lactate at the surface of the scaffold with different lactate-releasing ability. Fractal dimension of newly-established vessel loops allows precise characterizing the local microenvironment supporting cell growth on various types of gelatin scaffolds. © Springer International Publishing AG 2017.
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Держатели документа:
Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Salmin, V.; Morgun, A.; Khilazheva, E.; Pisareva, N.; Boitsova, E.; Lavrentiev, P.; Sadovsky, M.G.; Садовский, Михаил Георгиевич; Salmina, A.
Titanium nitride as light trapping plasmonic material in silicon solar cell
/ N. Venugopal [et al.] // Opt Mater. - 2017. - Vol. 72. - P397-402, DOI 10.1016/j.optmat.2017.06.035
. - ISSN 0925-3467
Кл.слова (ненормированные):
Photovoltaics -- Plasmonics -- Titanium nitride -- Absorption spectroscopy -- CMOS integrated circuits -- Efficiency -- Gold -- Metals -- MOS devices -- Nanoparticles -- Nanostructured materials -- Nitrides -- Optoelectronic devices -- Plasmons -- Semiconductor devices -- Silicon -- Silver -- Solar cells -- Solar power generation -- Thin film solar cells -- Thin films -- Time domain analysis -- Tin oxides -- Titanium -- Titanium compounds -- Titanium nitride -- Absorption enhancement -- Complementary metal oxide semiconductors -- Nanoparticle diameter -- Other opto-electronic devices -- Photovoltaics -- Plasmonic nanoparticle -- Plasmonics -- Thin-film silicon solar cells -- Silicon solar cells
Аннотация: Light trapping is a crucial prominence to improve the efficiency in thin film solar cells. However, last few years, plasmonic based thin film solar cells shows potential structure to improve efficiency in photovoltaics. In order to achieve the high efficiency in plasmonic based thin film solar cells, traditionally noble metals like Silver (Ag) and Gold (Au) are extensively used due to their ability to localize the light in nanoscale structures. In this paper, we numerically demonstrated the absorption enhancement due to the incorporation of novel plasmonic TiN nanoparticles on thin film Silicon Solar cells. Absorption enhancement significantly affected by TiN plasmonic nanoparticles on thin film silicon was studied using Finite-Difference-Time-Domain Method (FDTD). The optimal absorption enhancement 1.2 was achieved for TiN nanoparticles with the diameter of 100 nm. The results show that the plasmonic effect significantly dominant to achieve maximum absorption enhancement g(?) at longer wavelengths (red and near infrared) and as comparable with Au nanoparticle on thin film Silicon. The absorption enhancement can be tuned to the desired position of solar spectrum by adjusting the size of TiN nanoparticles. Effect of nanoparticle diameters on the absorption enhancement was also thoroughly analyzed. The numerically simulated results show that TiN can play the similar role as gold nanoparticles on thin film silicon solar cells. Furthermore, TiN plasmonic material is cheap, abundant and more Complementary Metal Oxide Semiconductor (CMOS) compatible material than traditional plasmonic metals like Ag and Au, which can be easy integration with other optoelectronic devices. © 2017 Elsevier B.V.
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Держатели документа:
Institute of Nanotechnology, Spectroscopy and Quantum Chemistry, Siberian Federal University, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Federal Research Center KSC SB RAS, Krasnoyarsk, Russian Federation
L.V. Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Venugopal, N.; Gerasimov, V. S.; Ershov, A. E.; Karpov, S. V.; Polyutov, S. P.
Кл.слова (ненормированные):
Photovoltaics -- Plasmonics -- Titanium nitride -- Absorption spectroscopy -- CMOS integrated circuits -- Efficiency -- Gold -- Metals -- MOS devices -- Nanoparticles -- Nanostructured materials -- Nitrides -- Optoelectronic devices -- Plasmons -- Semiconductor devices -- Silicon -- Silver -- Solar cells -- Solar power generation -- Thin film solar cells -- Thin films -- Time domain analysis -- Tin oxides -- Titanium -- Titanium compounds -- Titanium nitride -- Absorption enhancement -- Complementary metal oxide semiconductors -- Nanoparticle diameter -- Other opto-electronic devices -- Photovoltaics -- Plasmonic nanoparticle -- Plasmonics -- Thin-film silicon solar cells -- Silicon solar cells
Аннотация: Light trapping is a crucial prominence to improve the efficiency in thin film solar cells. However, last few years, plasmonic based thin film solar cells shows potential structure to improve efficiency in photovoltaics. In order to achieve the high efficiency in plasmonic based thin film solar cells, traditionally noble metals like Silver (Ag) and Gold (Au) are extensively used due to their ability to localize the light in nanoscale structures. In this paper, we numerically demonstrated the absorption enhancement due to the incorporation of novel plasmonic TiN nanoparticles on thin film Silicon Solar cells. Absorption enhancement significantly affected by TiN plasmonic nanoparticles on thin film silicon was studied using Finite-Difference-Time-Domain Method (FDTD). The optimal absorption enhancement 1.2 was achieved for TiN nanoparticles with the diameter of 100 nm. The results show that the plasmonic effect significantly dominant to achieve maximum absorption enhancement g(?) at longer wavelengths (red and near infrared) and as comparable with Au nanoparticle on thin film Silicon. The absorption enhancement can be tuned to the desired position of solar spectrum by adjusting the size of TiN nanoparticles. Effect of nanoparticle diameters on the absorption enhancement was also thoroughly analyzed. The numerically simulated results show that TiN can play the similar role as gold nanoparticles on thin film silicon solar cells. Furthermore, TiN plasmonic material is cheap, abundant and more Complementary Metal Oxide Semiconductor (CMOS) compatible material than traditional plasmonic metals like Ag and Au, which can be easy integration with other optoelectronic devices. © 2017 Elsevier B.V.
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Держатели документа:
Institute of Nanotechnology, Spectroscopy and Quantum Chemistry, Siberian Federal University, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Federal Research Center KSC SB RAS, Krasnoyarsk, Russian Federation
L.V. Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Venugopal, N.; Gerasimov, V. S.; Ershov, A. E.; Karpov, S. V.; Polyutov, S. P.
In Vivo Cancer Cells Elimination Guided by Aptamer-Functionalized Gold-Coated Magnetic Nanoparticles and Controlled with Low Frequency Alternating Magnetic Field
/ I. V. Belyanina [et al.] // Theranostics. - 2017. - Vol. 7, Is. 13. - P3326-3337, DOI 10.7150/thno.17089. - Cited References:35. - The authors are grateful to George Y. Vorogeikin, Yuri I. Vorogeikin and "OKB ART". Andrey Barinov and "OPTEC Group" for help with 3D laser scanning imaging. Microscopic analyses using Carl Zeiss LSM 800 were done in the "Center for bioassay, nanotechnology and nanomaterials safety" ("Biotest-Nano") (Multiple-Access Center, Tomsk State University, Tomsk, Russia). Toxicity studies have been performed in Multiple-Access Center, Central Scientific Research Laboratory in Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenecky. This work was supported by the Russian Scientific Fund (grant #14-15-00805).
. - ISSN 1838-7640
РУБ Medicine, Research & Experimental
Аннотация: Biomedical applications of magnetic nanoparticles under the influence of a magnetic field have been proved useful beyond expectations in cancer therapy. Magnetic nanoparticles are effective heat mediators, drug nanocarriers, and contrast agents; various strategies have been suggested to selectively target tumor cancer cells. Our study presents magnetodynamic nanotherapy using DNA aptamer-functionalized 50 nm gold-coated magnetic nanoparticles exposed to a low frequency alternating magnetic field for selective elimination of tumor cells in vivo. The cell specific DNA aptamer AS-14 binds to the fibronectin protein in Ehrlich carcinoma hence helps deliver the gold-coated magnetic nanoparticles to the mouse tumor. Applying an alternating magnetic field of 50 Hz at the tumor site causes the nanoparticles to oscillate and pull the fibronectin proteins and integrins to the surface of the cell membrane. This results in apoptosis followed by necrosis of tumor cells without heating the tumor, adjacent healthy cells and tissues. The aptamer-guided nanoparticles and the low frequency alternating magnetic field demonstrates a unique non-invasive nanoscalpel technology for precise cancer surgery at the single cell level.
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Держатели документа:
Krasnoyarsk State Med Univ, Krasnoyarsk, Russia.
Russian Acad Sci, KSC Siberian Branch, Fed Res Ctr, Krasnoyarsk, Russia.
Siberian Fed Univ, Krasnoyarsk, Russia.
Univ Ottawa, Dept Chem & Biomol Sci, Ottawa, ON, Canada.
Inst Computat Modeling RAS SB, Krasnoyarsk, Russia.
Доп.точки доступа:
Belyanina, Irina V.; Zamay, Tatiana N.; Zamay, Galina S.; Zamay, Sergey S.; Kolovskaya, Olga S.; Ivanchenko, Tatiana I.; Denisenko, Valery V.; Kirichenko, Andrey K.; Glazyrin, Yury E.; Garanzha, Irina V.; Grigorieva, Valentina V.; Shabanov, Alexandr V.; Veprintsev, Dmitry V.; Sokolov, Alexey E.; Sadovskii, Vladimir M.; Gargaun, Ana; Berezovski, Maxim V.; Kichkailo, Anna S.; Russian Scientific Fund [14-15-00805]
Рубрики:
PHOTOTHERMAL THERAPY
INTEGRIN ACTIVATION
FIBRONECTIN
STIMULATION
Кл.слова (ненормированные):
cancer therapy -- gold coated magnetic nanoparticles -- DNA aptamers -- low -- frequency alternating magnetic field -- fibronectin -- integrin -- apoptosis -- necrosis
PHOTOTHERMAL THERAPY
INTEGRIN ACTIVATION
FIBRONECTIN
STIMULATION
Кл.слова (ненормированные):
cancer therapy -- gold coated magnetic nanoparticles -- DNA aptamers -- low -- frequency alternating magnetic field -- fibronectin -- integrin -- apoptosis -- necrosis
Аннотация: Biomedical applications of magnetic nanoparticles under the influence of a magnetic field have been proved useful beyond expectations in cancer therapy. Magnetic nanoparticles are effective heat mediators, drug nanocarriers, and contrast agents; various strategies have been suggested to selectively target tumor cancer cells. Our study presents magnetodynamic nanotherapy using DNA aptamer-functionalized 50 nm gold-coated magnetic nanoparticles exposed to a low frequency alternating magnetic field for selective elimination of tumor cells in vivo. The cell specific DNA aptamer AS-14 binds to the fibronectin protein in Ehrlich carcinoma hence helps deliver the gold-coated magnetic nanoparticles to the mouse tumor. Applying an alternating magnetic field of 50 Hz at the tumor site causes the nanoparticles to oscillate and pull the fibronectin proteins and integrins to the surface of the cell membrane. This results in apoptosis followed by necrosis of tumor cells without heating the tumor, adjacent healthy cells and tissues. The aptamer-guided nanoparticles and the low frequency alternating magnetic field demonstrates a unique non-invasive nanoscalpel technology for precise cancer surgery at the single cell level.
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Смотреть статью
Держатели документа:
Krasnoyarsk State Med Univ, Krasnoyarsk, Russia.
Russian Acad Sci, KSC Siberian Branch, Fed Res Ctr, Krasnoyarsk, Russia.
Siberian Fed Univ, Krasnoyarsk, Russia.
Univ Ottawa, Dept Chem & Biomol Sci, Ottawa, ON, Canada.
Inst Computat Modeling RAS SB, Krasnoyarsk, Russia.
Доп.точки доступа:
Belyanina, Irina V.; Zamay, Tatiana N.; Zamay, Galina S.; Zamay, Sergey S.; Kolovskaya, Olga S.; Ivanchenko, Tatiana I.; Denisenko, Valery V.; Kirichenko, Andrey K.; Glazyrin, Yury E.; Garanzha, Irina V.; Grigorieva, Valentina V.; Shabanov, Alexandr V.; Veprintsev, Dmitry V.; Sokolov, Alexey E.; Sadovskii, Vladimir M.; Gargaun, Ana; Berezovski, Maxim V.; Kichkailo, Anna S.; Russian Scientific Fund [14-15-00805]
Численный анализ температурных данных с пленочных терморезисторов электронных плат
[Текст] : статья / Анна Анатольевна Корнеева, Владимир Владимирович Шайдуров // Вычислительные технологии. - 2017. - Т. 22, № 3. - С. 32-44
. - ISSN 1560-7534
Перевод заглавия: Numerical analysis of temperature data from film thermistors of electronic boards
Кл.слова (ненормированные):
радиоэлектронная плата -- пленочный терморезистор -- физико-математическая модель -- численный алгоритм -- electronic boards -- film thermistors -- physical-mathematical model -- numerical algorithms
Аннотация: Предложен алгоритм определения участков перегрева печатной платы с радио-электронными элементами и температуры перегрева. В основе алгоритма лежат физико-математическая модель процесса нагрева и дополнительные качественные характеристики исследуемых состояний печатной платы. Приводятся результаты вычислительных экспериментов, иллюстрирующих работоспособность алгоритма.
In this paper, the printed circuit board with electronic components is considered as a geometric structure consisted of rectangular cells coated by thin film thermistors whose local resistance essentially depends on the local temperature of the cell. Resistance measurement of long conductors is not carried out locally but rather on the horizontal and vertical segments. Therefore, the amount of these data on the resistance of the conductors is considerably less than the number of local resistances of all cells. However, using physical and qualitative considerations in some cases, it is possible to obtain the numerical solution. In particular, during functioning of the board, an overheating of individual elements may occur, resulting in temperature rise of the respective cells with corresponding increase of resistance of some circuit segments. In the paper, the problem for identifying such cells with overheating as well as their temperature using two additional physical considerations is set. Firstly, while overheating an element, the temperature of any cell cannot reduce. Secondly, the temperature gradient is mitigated by the heat transfer between the elements and cells. The mathematical formulation of these considerations leads to a non-singular system of linear equations for the determining of the overheating cells and their approximate temperature. The presented algorithms and computational experiments demonstrate the applicability of this approach.
РИНЦ
Держатели документа:
Институт вычислительного моделирования СО РАН
Институт космических и информационных технологий СФУ
Доп.точки доступа:
Корнеева, Анна Анатольевна; Korneeva Anna Anatolievna; Шайдуров, Владимир Владимирович; Shaydurov Vladimir Vladimirovich
Перевод заглавия: Numerical analysis of temperature data from film thermistors of electronic boards
Кл.слова (ненормированные):
радиоэлектронная плата -- пленочный терморезистор -- физико-математическая модель -- численный алгоритм -- electronic boards -- film thermistors -- physical-mathematical model -- numerical algorithms
Аннотация: Предложен алгоритм определения участков перегрева печатной платы с радио-электронными элементами и температуры перегрева. В основе алгоритма лежат физико-математическая модель процесса нагрева и дополнительные качественные характеристики исследуемых состояний печатной платы. Приводятся результаты вычислительных экспериментов, иллюстрирующих работоспособность алгоритма.
In this paper, the printed circuit board with electronic components is considered as a geometric structure consisted of rectangular cells coated by thin film thermistors whose local resistance essentially depends on the local temperature of the cell. Resistance measurement of long conductors is not carried out locally but rather on the horizontal and vertical segments. Therefore, the amount of these data on the resistance of the conductors is considerably less than the number of local resistances of all cells. However, using physical and qualitative considerations in some cases, it is possible to obtain the numerical solution. In particular, during functioning of the board, an overheating of individual elements may occur, resulting in temperature rise of the respective cells with corresponding increase of resistance of some circuit segments. In the paper, the problem for identifying such cells with overheating as well as their temperature using two additional physical considerations is set. Firstly, while overheating an element, the temperature of any cell cannot reduce. Secondly, the temperature gradient is mitigated by the heat transfer between the elements and cells. The mathematical formulation of these considerations leads to a non-singular system of linear equations for the determining of the overheating cells and their approximate temperature. The presented algorithms and computational experiments demonstrate the applicability of this approach.
РИНЦ
Держатели документа:
Институт вычислительного моделирования СО РАН
Институт космических и информационных технологий СФУ
Доп.точки доступа:
Корнеева, Анна Анатольевна; Korneeva Anna Anatolievna; Шайдуров, Владимир Владимирович; Shaydurov Vladimir Vladimirovich
Временная динамика структурных и функциональных характеристик енисейского фитопланктона в нижнем бьефе Красноярской ГЭС
[Текст] : научное издание / Юлия Андреевна Пономарева, Полина Владимировна Постникова // Вестник Томского государственного университета. Биология. - 2017. - № 38. - С. 167-182, DOI 10.17223/19988591/38/10
. - ISSN 1998-8591
Перевод заглавия: Temporal dynamics of structural and functional characteristics of the Yenisei river phytoplankton downstream of the Krasnoyarsk hydroelectric power station
Кл.слова (ненормированные):
Bacillariophyta -- Yenisei River -- downstream -- cell size -- chlorophyll а -- река Енисей -- нижний бьеф -- размер клеток -- хлорофилл а
Аннотация: Представлены результаты изучения формирования фитопланктонного сообщества и флуоресцентных характеристик вод в условиях сброса высоконапорной Красноярской ГЭС. Сезонные и межгодовые изменения фитопланктона оценивали на основе численности и биомассы клеток фитопланктона, а также концентрации хлорофилла а. Выявлены закономерности сезонных сукцессий и межгодовых вариаций структурно-функциональных характеристик фитопланктона. Обнаружено, что основу флористического списка в реке Енисей составляют диатомовые водоросли (66% от общего видового состава), преобладающие в планктоне во все сезоны года. Наибольший вклад в общую численность и биомассу фитопланктона вносят нанофитопланктон (2-20 мкм) и микрофитопланктон (20-64 мкм). В комплекс доминантов вранневесенний период входили Diatoma vulgare Bory и Hannaea arcus (Ehrb.) Patr., в летний - Aulacoseira islandica (O. Mull.) Sim. и Cyclotella radiosa (Grun.) Lemm., позднелетний - Fragilaria crotonensis Kitt. Вместе с тем на фоне увеличивающегося видового разнообразия и интенсивного развития водорослей в весенне-летний период отмечен спад концентрации хлорофилла а. Установлено, что во все рассматриваемые годы пики численности и биомассы фитопланктона приходятся на июнь за счет колониальных диатомовых водорослей, попадающих в нижний бьеф со стоком из верхнего бьефа.
The Yenisei River is the biggest waterway in Siberia. In the second half of the 20th century, the Yenisei River was overlapped by dams, and it deeply damaged the natural hydrological, hydrochemical and hydrobiological regimes of the river. As a result of constructing the Krasnoyarsk hydroelectric power station, a significant river component - phytoplankton, which occupies the central place in the formation of the aquatic ecosystem - has changed downstream of the river. In the river, phytoplankton is formed from phytoperiphyton and allochthonous algae, including phytoplankton species of upstream reservoirs. Therefore, knowledge of transformation laws of phytoplankton species composition, which occurs during the regulation of the river flow and formation of reservoirs, may contribute to the development of ideas about changing the aquatic communities. The aim of this research was to explore the formation of phytoplankton under the conditions of water discharge in the Krasnoyarsk HPS and to study chlorophyll a concentration. We collected phytoplankton samples at a distance of 34 km below the Krasnoyarsk HPS (55°59'1.8"N, 92°47'13.4"E) in 2008-2014 and analyzed them according standard hydrobiological methods (See Table). In 2012-2014, we measured fluorescent water characteristics along with the study of algae. We took the nomenclature for algae considering taxonomic transformations according to the system adopted by the International algae database (http://www.algaebase.org). A quantitative processing of phytoplankton samples was conducted daily, species composition and biomass of algae was determined weekly. In size, algae cells were differentiated according to Rainey. The degree of complexity of phytoplankton communities was determined calculating the Shannon species diversity index (by biomass). The dominant algae included species making the main contribution into the total phytoplankton biomass. In 20122014, along with the study of algae, we determined chlorophyll а concentration by fluorimetric method, weekly (See Fig. 3). We collected and processed a total of 2453 qualitative and quantitative phytoplankton samples for the period of study; 89 samples to determine chlorophyll а content. Altogether, we found 99 species, kinds and forms of algae from 6 groups in the river phytoplankton. In the Yenisei River, diatoms, which predominate in plankton in all seasons, are characterized by the maximum number of species. There is a certain sequence in the appearance of dominant algae. From late April to late May, Diatoma vulgare Bory and Hannaea arcus (Ehrb.) Patr. were recorded in quantities, in June -Aulacoseira islandica (O. Mull.) Sim., in July - Cyclotella radiosa (Grun.) Lemm., in August - Fragilaria crotonensis Kitt. (See Fig. 1). Upstream of the Krasnoyarsk reservoir A. islandica had a dominant position in nephotic cold layer in June, in July and August - C. radiosa; F. crotonensis was a subdominant. It is known that deep water discharge through the dam (18-40 м) is specific for the Krasnoyarsk reservoir. This causes the flow of algae over the dam. In general, the dynamics of the total number and the total biomass of phytoplankton had the form of unimodal curve within the year (with a peak in June) (See Fig. 2). Nanophytoplankton (2-20 mkm) and microphytoplankton (20-64 mkm) made the biggest contribution to the total biomass of phytoplankton. We recorded peaks of number and biomass of phytoplankton in June in all years in question. We found that the percentage of chlorophyll content per phytoplankton biomass unit had seasonal variations and increased in winter (See Fig. 5). It is known, that the concentration of chlorophyll a depends on dimensional structure of phytoplankton. In spring and summer, the domination of algae cells with bigger volumes in phytoplankton caused a decrease in chlorophyll а concentration.
РИНЦ
Держатели документа:
Институт вычислительного моделирования СО РАН
Доп.точки доступа:
Пономарева, Юлия Андреевна; Ponomareva Yulia A.; Постникова, Полина Владимировна; Postnikova Polina V.
Перевод заглавия: Temporal dynamics of structural and functional characteristics of the Yenisei river phytoplankton downstream of the Krasnoyarsk hydroelectric power station
Кл.слова (ненормированные):
Bacillariophyta -- Yenisei River -- downstream -- cell size -- chlorophyll а -- река Енисей -- нижний бьеф -- размер клеток -- хлорофилл а
Аннотация: Представлены результаты изучения формирования фитопланктонного сообщества и флуоресцентных характеристик вод в условиях сброса высоконапорной Красноярской ГЭС. Сезонные и межгодовые изменения фитопланктона оценивали на основе численности и биомассы клеток фитопланктона, а также концентрации хлорофилла а. Выявлены закономерности сезонных сукцессий и межгодовых вариаций структурно-функциональных характеристик фитопланктона. Обнаружено, что основу флористического списка в реке Енисей составляют диатомовые водоросли (66% от общего видового состава), преобладающие в планктоне во все сезоны года. Наибольший вклад в общую численность и биомассу фитопланктона вносят нанофитопланктон (2-20 мкм) и микрофитопланктон (20-64 мкм). В комплекс доминантов вранневесенний период входили Diatoma vulgare Bory и Hannaea arcus (Ehrb.) Patr., в летний - Aulacoseira islandica (O. Mull.) Sim. и Cyclotella radiosa (Grun.) Lemm., позднелетний - Fragilaria crotonensis Kitt. Вместе с тем на фоне увеличивающегося видового разнообразия и интенсивного развития водорослей в весенне-летний период отмечен спад концентрации хлорофилла а. Установлено, что во все рассматриваемые годы пики численности и биомассы фитопланктона приходятся на июнь за счет колониальных диатомовых водорослей, попадающих в нижний бьеф со стоком из верхнего бьефа.
The Yenisei River is the biggest waterway in Siberia. In the second half of the 20th century, the Yenisei River was overlapped by dams, and it deeply damaged the natural hydrological, hydrochemical and hydrobiological regimes of the river. As a result of constructing the Krasnoyarsk hydroelectric power station, a significant river component - phytoplankton, which occupies the central place in the formation of the aquatic ecosystem - has changed downstream of the river. In the river, phytoplankton is formed from phytoperiphyton and allochthonous algae, including phytoplankton species of upstream reservoirs. Therefore, knowledge of transformation laws of phytoplankton species composition, which occurs during the regulation of the river flow and formation of reservoirs, may contribute to the development of ideas about changing the aquatic communities. The aim of this research was to explore the formation of phytoplankton under the conditions of water discharge in the Krasnoyarsk HPS and to study chlorophyll a concentration. We collected phytoplankton samples at a distance of 34 km below the Krasnoyarsk HPS (55°59'1.8"N, 92°47'13.4"E) in 2008-2014 and analyzed them according standard hydrobiological methods (See Table). In 2012-2014, we measured fluorescent water characteristics along with the study of algae. We took the nomenclature for algae considering taxonomic transformations according to the system adopted by the International algae database (http://www.algaebase.org). A quantitative processing of phytoplankton samples was conducted daily, species composition and biomass of algae was determined weekly. In size, algae cells were differentiated according to Rainey. The degree of complexity of phytoplankton communities was determined calculating the Shannon species diversity index (by biomass). The dominant algae included species making the main contribution into the total phytoplankton biomass. In 20122014, along with the study of algae, we determined chlorophyll а concentration by fluorimetric method, weekly (See Fig. 3). We collected and processed a total of 2453 qualitative and quantitative phytoplankton samples for the period of study; 89 samples to determine chlorophyll а content. Altogether, we found 99 species, kinds and forms of algae from 6 groups in the river phytoplankton. In the Yenisei River, diatoms, which predominate in plankton in all seasons, are characterized by the maximum number of species. There is a certain sequence in the appearance of dominant algae. From late April to late May, Diatoma vulgare Bory and Hannaea arcus (Ehrb.) Patr. were recorded in quantities, in June -Aulacoseira islandica (O. Mull.) Sim., in July - Cyclotella radiosa (Grun.) Lemm., in August - Fragilaria crotonensis Kitt. (See Fig. 1). Upstream of the Krasnoyarsk reservoir A. islandica had a dominant position in nephotic cold layer in June, in July and August - C. radiosa; F. crotonensis was a subdominant. It is known that deep water discharge through the dam (18-40 м) is specific for the Krasnoyarsk reservoir. This causes the flow of algae over the dam. In general, the dynamics of the total number and the total biomass of phytoplankton had the form of unimodal curve within the year (with a peak in June) (See Fig. 2). Nanophytoplankton (2-20 mkm) and microphytoplankton (20-64 mkm) made the biggest contribution to the total biomass of phytoplankton. We recorded peaks of number and biomass of phytoplankton in June in all years in question. We found that the percentage of chlorophyll content per phytoplankton biomass unit had seasonal variations and increased in winter (See Fig. 5). It is known, that the concentration of chlorophyll a depends on dimensional structure of phytoplankton. In spring and summer, the domination of algae cells with bigger volumes in phytoplankton caused a decrease in chlorophyll а concentration.
РИНЦ
Держатели документа:
Институт вычислительного моделирования СО РАН
Доп.точки доступа:
Пономарева, Юлия Андреевна; Ponomareva Yulia A.; Постникова, Полина Владимировна; Postnikova Polina V.
612.35
И 37
И 37
Изменение генерации активных форм кислорода в печени после введения биогенного ферригидрита
[Текст] : статья / Вера Геннадьевна Пахомова [и др.] // Здоровье. Медицинская экология. Наука. - 2017. - Т. 70, № 3. - С. 136-139, DOI 10.5281/zenodo.817825
. - ISSN 2075-4108
Перевод заглавия: The introduction of biognetic ferryhydritis affects on the generation of reactive oxygen species in the liver
Кл.слова (ненормированные):
биогенный ферригидрит -- наночастицы -- АФК -- хемилюминесценция -- изолированная перфузия -- печень -- biogenic ferrihydrite -- nanoparticles -- ros -- chemiluminescent analysis -- isolated perfusion -- liver
Аннотация: Цель работы - анализ генерации активных форм кислорода (АФК) клетками печени крысы при воздействии наночастиц ферригидрита. Материалы и методы. Анализ биологической активности ферригидрита проводили на модели изолированной культивируемой печени крысы. Изменение генерации АФК в клетках печени определяли методом хемилюминесцентного анализа. В качестве люминесцентных зондов использовали люминол и люцигенин. В результате проведенного исследования показано, что наночастицы биогенного ферригидрита способствуют усилению генерации активных форм кислорода в клетках печени.
The aim of this work is to analyze the generation of reactive oxygen species (ROS) by rat liver cells after exposed to ferrihydrite nanoparticles. Materials and methods. The test of the biological activity of ferrihydrite was carried out on the model of an isolated cultured rat liver. The change in the ROS generation by liver cells was determined by the method of chemiluminescent analysis. Luminol and lucigenin were used as luminescent enhancer. The results were shown that nanoparticles of biogenic ferrihydrite promote the generation of ROS by liver cells.
РИНЦ
Держатели документа:
Федеральное государственное бюджетное научное учреждение «Федеральный исследовательский центр «Красноярский научный центр Сибирского отделения Российской академии наук»
Федеральное государственное бюджетное образовательное учреждение высшего образования «Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Министерства здравоохранения Российской Федерации
Доп.точки доступа:
Пахомова, Вера Геннадьевна; Шадрин, Константин Викторович; Макарская, Галина Владимировна; Тарских, Светлана Вениаминовна; Рупенко, Александр Петрович; Крюкова, Ольга Витальевна; Гуревич, Юрий Леонидович
Перевод заглавия: The introduction of biognetic ferryhydritis affects on the generation of reactive oxygen species in the liver
| УДК |
Кл.слова (ненормированные):
биогенный ферригидрит -- наночастицы -- АФК -- хемилюминесценция -- изолированная перфузия -- печень -- biogenic ferrihydrite -- nanoparticles -- ros -- chemiluminescent analysis -- isolated perfusion -- liver
Аннотация: Цель работы - анализ генерации активных форм кислорода (АФК) клетками печени крысы при воздействии наночастиц ферригидрита. Материалы и методы. Анализ биологической активности ферригидрита проводили на модели изолированной культивируемой печени крысы. Изменение генерации АФК в клетках печени определяли методом хемилюминесцентного анализа. В качестве люминесцентных зондов использовали люминол и люцигенин. В результате проведенного исследования показано, что наночастицы биогенного ферригидрита способствуют усилению генерации активных форм кислорода в клетках печени.
The aim of this work is to analyze the generation of reactive oxygen species (ROS) by rat liver cells after exposed to ferrihydrite nanoparticles. Materials and methods. The test of the biological activity of ferrihydrite was carried out on the model of an isolated cultured rat liver. The change in the ROS generation by liver cells was determined by the method of chemiluminescent analysis. Luminol and lucigenin were used as luminescent enhancer. The results were shown that nanoparticles of biogenic ferrihydrite promote the generation of ROS by liver cells.
РИНЦ
Держатели документа:
Федеральное государственное бюджетное научное учреждение «Федеральный исследовательский центр «Красноярский научный центр Сибирского отделения Российской академии наук»
Федеральное государственное бюджетное образовательное учреждение высшего образования «Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Министерства здравоохранения Российской Федерации
Доп.точки доступа:
Пахомова, Вера Геннадьевна; Шадрин, Константин Викторович; Макарская, Галина Владимировна; Тарских, Светлана Вениаминовна; Рупенко, Александр Петрович; Крюкова, Ольга Витальевна; Гуревич, Юрий Леонидович