Труды сотрудников ИВМ СО РАН

/ V. S. Gerasimov [et al.] // Colloid J. - 2016. - Vol. 78, Is. 4. - P435-442, DOI 10.1134/S1061933X16040050 . - ISSN 1061-933X
Аннотация: Selective action of laser radiation on membranes of malignant cells has been studied in different regimes using conjugates of gold nanoparticles with oligonucleotides by the example of DNA aptamers. Under the conditions of a contact between a bioconjugate and a cell surface and the development of substantial and rapidly relaxing temperature gradients near a nanoparticle, the membranes of malignant cells alone are efficiently damaged due to the local hyperthermia of a cellular membrane. It has been shown that employment of pulsed instead of continuous wave laser radiation provides the localization of the damaging action, which does not involve healthy cells. © 2016, Pleiades Publishing, Ltd.

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Держатели документа:
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, Russian Federation
Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, Russian Federation
Kirenskii Institute of Physics, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/38, Krasnoyarsk, Russian Federation
Reshetnev State Siberian State Aerospace University, pr. Gazety “Krasnoyarskii rabochii” 31, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Gerasimov, V. S.; Ershov, A. E.; Karpov, S. V.; Polyutov, S. P.; Semina, P. N.

/ V. Salmin [et al.] // (26 April 2017 through 28 April 2017 : Springer Verlag, 2017. - Vol. 10208 LNCS. - P591-601, DOI 10.1007/978-3-319-56148-6_53 . -
Аннотация: We studied the model of cerebral angiogenesis in vitro using lactate-releasing gelatin bioscaffolds and primary culture of brain endothelial cells. We found that development of microvessels from actively proliferating rat brain microvessels endothelial cells was greatly modified by the presence of lactate at the surface of the scaffold with different lactate-releasing ability. Fractal dimension of newly-established vessel loops allows precise characterizing the local microenvironment supporting cell growth on various types of gelatin scaffolds. © Springer International Publishing AG 2017.

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Держатели документа:
Research Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, p. Zheleznyaka str., 1, Krasnoyarsk, Russian Federation
Institute of Computational Modelling of SB RAS, Akademgorodok, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Salmin, V.; Morgun, A.; Khilazheva, E.; Pisareva, N.; Boitsova, E.; Lavrentiev, P.; Sadovsky, M.G.; Садовский, Михаил Георгиевич; Salmina, A.

/ Y. Gaponenko, A. Mialdun, V. Shevtsova // Phys. Fluids. - 2018. - Vol. 30, Is. 6, DOI 10.1063/1.5032107 . - ISSN 1070-6631
Аннотация: We develop a connection between instabilities in a two-liquid miscible system and in a liquid mixture with a linear distribution of density. In both cases, the liquids are placed in a closed cell and subjected to horizontal oscillations at different frequencies and amplitudes in a microgravity environment. The study includes parabolic flight experiments and numerical simulations. We examine the transformation of the interfacial pattern when the diffusive interface widens from a thin transient zone occupying 4% of the cell height to a situation when it occupies the entire cell height. In the case of sharp concentration (density) difference between miscible liquids, under reduced gravity conditions, instability leads to the formation of rectangular columns of liquids of alternating densities with an amplitude nearly equal to the height of the cell. The increase of the interface width promotes the selection of a smaller wave number associated with columns. The experimental observations are confirmed by the numerical simulations. In order to quantify the pattern regimes, we suggested to use the averaged mass flux through the mid-height of the cell. © 2018 Author(s).

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Держатели документа:
MRC, CP165/62, Universite Libre de Bruxelles, Ave. Franklin Roosevelt, 50, Brussels, Belgium
Institute of Computational Modelling, SB RAS, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Gaponenko, Y.; Mialdun, A.; Shevtsova, V.

/ A. S. Fedotova [et al.] // IOP Conference Series: Earth and Environmental Science : Institute of Physics Publishing, 2019. - Vol. 315: International Scientific Conference on Agribusiness, Environmental Engineering and Biotechnologies, AGRITECH 2019 (20 June 2019 through 22 June 2019, ) Conference code: 152072, Is. 4. - Ст. 042017, DOI 10.1088/1755-1315/315/4/042017 . -
Аннотация: The article contains the results of hematological, immunological and chemiluminescent analysis of the functional activity of peripheral blood cells of five-year-old lactating cows from the central regions of the Krasnoyarsk Territory (Siberia, Russia) with different radiation status, at which the radiation doses of animals were 0.02, 0.17 and 0.21 mSv per year. It was established that small doses of radiation at 0.17 mSv per year and 0.21 mSv per year affect hematological parameters, increase the phagocytic activity of blood leukocytes and change the kinetics of the formation of active oxygen forms by blood cells, which is manifested as an increase in the time of formation of the maximum kinetics of spontaneous and activated secondary radicals, reduction of the total production of secondary radicals in the antigenic activation of blood cells in vitro and an increase in the volume of spontaneously produced primary radicals. © 2019 IOP Publishing Ltd. All rights reserved.

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Держатели документа:
Krasnoyarsk State Agrarian University, 90 Mira ane., Krasnoyarsk, 660049, Russian Federation
Institute of Computational Modeling SB RAS, 50/44 Akademgorodok, Krasnoyarsk, 660036, Russian Federation
ISC Research Center for Extreme States of the Body at the Presidium of the FIC KSC SB RAS, 50/12 Akademgorodok, Krasnoyarsk, 660036, Russian Federation

Доп.точки доступа:
Fedotova, A. S.; Turitsina, E. G.; Makarskaya, G. V.; Tarskikh, S. V.

/ N. N. Lukzen, K. L. Ivanov, V. M. Sadovsky, R. Z. Sagdeev // J Chem Phys. - 2020. - Vol. 152, Is. 3. - Ст. 034103, DOI 10.1063/1.5131583 . - ISSN 0021-9606
Аннотация: Magnetic Field Effects (MFEs) on the recombination of radicals, which diffuse on an infinite plane, are studied theoretically. The case of spin-selective diffusion-controlled recombination of Radical Pairs (RPs) starting from a random spin state is considered assuming uniform initial distribution of the radicals. In this situation, reaction kinetics is described by a time-dependent rate coefficient K(t), which tends to zero at long times. Strong MFEs on K(t) are predicted that originate from the ?g and hyperfine driven singlet-triplet mixing in the RP. The effects of spin relaxation on the magnetic field are studied, as well as the influence of the dipole-dipole interaction between the electron spins of the RP. In the two-dimensional case, this interaction is not averaged out by diffusion and it strongly affects the MFE. The results of this work are of importance for interpreting MFEs on lipid peroxidation, a magnetosensitive process occurring on two-dimensional surfaces of cell membranes. © 2020 Author(s).

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Держатели документа:
International Tomography Center, Siberian Branch, Russian Academy of Sciences, Institutskaya Str. 3a, Novosibirsk, 630090, Russian Federation
Novosibirsk State University, Pirogova Str. 1, Novosibirsk, 630090, Russian Federation
Institute of Computational Modeling, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/44, Krasnoyarsk, 660036, Russian Federation
Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Science, Leninskii Prospect 31, Moscow, 19991, Russian Federation

Доп.точки доступа:
Lukzen, N. N.; Ivanov, K. L.; Sadovsky, V. M.; Sagdeev, R. Z.