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    Nanodiamonds as Carriers for Address Delivery of Biologically Active Substances
[Text] / K.V. Purtov [et al.] // Nanoscale Res. Lett. - 2010. - Vol. 5, Is. 3. - pp. 631-636, DOI 10.1007/s11671-010-9526-0. - Cited References: 24. - This work was supported by the Program # 27 for Basic Research of the Presidium of RAS (project 3.6.3). . - ISSN 1931-7573
РУБ Nanoscience & Nanotechnology + Materials Science, Multidisciplinary + Physics, Applied

Аннотация: Surface of detonation nanodiamonds was functionalized for the covalent attachment of immunoglobulin, and simultaneously bovine serum albumin and Rabbit Anti-Mouse Antibody. The nanodiamond-IgG(I125) and RAM-nanodiamond-BSA(I125) complexes are stable in blood serum and the immobilized proteins retain their biological activity. It was shown that the RAM-nanodiamond-BSA(I125) complex is able to bind to the target antigen immobilized on the Sepharose 6B matrix through antibody-antigen interaction. The idea can be extended to use nanodiamonds as carriers for delivery of bioactive substances (i.e., drugs) to various targets in vivo.


Доп.точки доступа:
Purtov, K.V.; Petunin, A.I.; Burov, A.E.; Буров, Андрей Ефимович; Puzyr, A.P.; Bondar, V.S.
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    SELF-ORGANIZED AGGREGATION OF A TRIPLE OF COLLOIDAL QUANTUM DOTS INTO STABLE STRUCTURES WITH VARIOUS SHAPES CONTROLLED BY A LASER FIELD
/ V. S. Kornienko, A. S. Tsipotan, A. S. Aleksandrovsky, V. V. Slabko // 10TH ANNIVERSARY INTERNATIONAL CONFERENCE ON NANOMATERIALS - RESEARCH & : TANGER LTD, 2019. - 10th Anniversary International Conference on Nanomaterials - Research (OCT 17-19, 2018, Brno, CZECH REPUBLIC). - P14-17. - Cited References:11. - The reported study was funded by Russian Science Foundation (Grant 18-72-00003). V.V. Slabko is grateful for the support from the Ministry of Education and Science of the Russian Federation (Grant 3.6341.2017/VU). . - ISBN 978-80-87294-89-5
РУБ Nanoscience & Nanotechnology
Рубрики:
NANOPARTICLES
Кл.слова (ненормированные):
Nanoparticles -- nanostructure -- self-assembly -- quantum dots

Аннотация: Dynamical model of self-assembly of nanoparticles in the field of laser radiation is developed and applied to the investigation of the possibility of the assembly of variously shaped structures comprised of the particles. Specifically, the computer model of the process of formation of structures with pre-defined geometry from a set of three initially isolated nanoparticles. The possibility of control of the geometry of the formed structure via the choice of the wavelength of external field.

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Держатели документа:
Siberian Fed Univ, RAS, Fed Res Ctr KSC SB, Dept Computat Math,Inst Computat Modeling, Krasnoyarsk, Russia.
Siberian Fed Univ, Krasnoyarsk, Russia.
RAS, Fed Res Ctr KSC SB, Kirensky Inst Phys, Lab Coherent Opt, Krasnoyarsk, Russia.

Доп.точки доступа:
Kornienko, Victoria S.; Tsipotan, Aleksei S.; Aleksandrovsky, Aleksandr S.; Slabko, Vitaliy V.; Russian Science FoundationRussian Science Foundation (RSF) [18-72-00003]; Ministry of Education and Science of the Russian FederationMinistry of Education and Science, Russian Federation [3.6341.2017/VU]
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