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Автор(ы) : Anand A., Saran M., Chaudhary S., Ronin R. S., Swami A. K., Mathur M., Burov A., Bagaria A.
Заглавие : A Novel Approach Towards Green Synthesis of Nanodiamonds as Biocompatible Agents
Место публикации : J. Nano. Electron. Phys.: Sumy State University, 2021. - Vol. 13, Is. 3. - С. 1-6. - ISSN 20776772 (ISSN), DOI 10.21272/jnep.13(3).03040
Аннотация: The application of nanobiotechnology is an emerging area of nanoscience and nanotechnology. Nanodi-amond has been a potent antibacterial, antifungal, antioxidant, and antiplatelet agent. In the present study, nanodiamonds were reduced by green synthesis and characterization was done through SEM, TEM, FTIR, and XRD. Further they were tested for their biological applications. The antimicrobial activity was investigated/studied/examined? through well diffusion method. The best activity was observed against Trichoderma reesei (16 mm) at 140 ?g/ml. The antioxidant activity was investigated through DPPH and FRAPS method. It was observed that the biologically reduced nanodiamonds reduce the Fe3+ ions to Fe2+ ions at 600 mM/l/g concentration. In DPPH assay, inhibitory concentration was found to be 4.58 ?g/ml. Further the antiplatelet activity was investigated by prothrombin time (PT) and activated partial throm-boplastin time (APTT) assay, and it was observed that biologically reduced nanodiamonds have potent an-tiplatelet activity. © 2021 Sumy State University
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