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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Prokhorenkov V. I., Vasil’eva E. Y., Puzyr’ A. P., Bondar’ V. S.
Заглавие : Effects of Nanodiamonds of Explosive Synthesis on the Skin of Experimental Animals Locally Exposed to Cobalt and Chrome Ions
Место публикации : Bull. Exp. Biol. Med. - 2014. - Vol. 158, Is. 2. - С. 264-267. - ISSN 00074888 (ISSN) , DOI 10.1007/s10517-014-2737-0
Ключевые слова (''Своб.индексиров.''): allergic contact dermatitis--chrome--cobalt--ions of bivalent metals--nanodiamonds--chromium--cobalt--nanodiamond--adsorption--animal--chemistry--dermatitis, allergic contact--drug effects--guinea pig--nonparametric test--skin--adsorption--animals--chromium--cobalt--dermatitis, allergic contact--guinea pigs--nanodiamonds--skin--statistics, nonparametric
Аннотация: Experiments in vivo demonstrated the protective effect of modified nanodiamonds on guinea pig skin after local exposure cobalt ions, but not chrome ions. The observed differences are determined by different adsorption of these ions by nanodiamonds: in vitro experiments showed that nanodiamonds adsorbed cobalt ions, but not chrome ions from water solutions. The perspectives of using modified nanodiamonds as a new adsorbent for prevention of allergic contact dermatitis induced by ions of bivalent metals are discussed. © 2014, Springer Science+Business Media New York.
Scopus
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Mogilnaya O.A., Puzyr A.P., Baron A.V., Bondar V.S.
Заглавие : Hematological Parameters and the State of Liver Cells of Rats After Oral Administration of Aflatoxin B1 Alone and Together with Nanodiamonds
Колич.характеристики :5 с
Коллективы :
Место публикации : Nanoscale Res. Lett.: SPRINGER, 2010. - Vol. 5, Is. 5. - С. 908-912. - ISSN 1931-7573, DOI 10.1007/s11671-010-9571-8
Примечания : Cited References: 23. - The study was financially supported by the Russian Foundation for Basic Research (RFBR) (Grant No. 06-0490234) and the RAS Presidium (Program No. 27, Project No. 64).
Предметные рубрики: B-1
MYCOTOXINS
ADSORPTION
Ключевые слова (''Своб.индексиров.''): nanodiamonds--aflatoxin b(1)--detoxification--adsorbent
Аннотация: Hematological parameters and the state of liver cells of rats were examined in vivo after the animals received aflatoxin B(1) (AfB(1)) alone and together with modified nanodiamonds (MND) synthesized by detonation. The rats that had received the MND hydrosol had elevated leukocyte levels, mainly due to higher granulocyte counts and somewhat increased monocyte counts compared to control rats. Hematological parameters of the rats that had received AfB(1) alone differed from those of the control rats in another way: total white blood cell counts were significantly lower due to the decreased lymphocyte counts. In rats that had consumed AfB(1) with the MND hydrosol, changes in hematological parameters were less pronounced than in rats that had consumed either AfB(1) or MND. Electron microscopy showed that hepatocytes of the rats that had received the MND hydrosol or AfB(1) with the MND hydrosol contained elevated levels of lipid inclusions and lysosomes. Hyperplasia of the smooth endoplasmic reticulum (EPR) was revealed in liver specimens of the rats that had received AfB(1). Results of the study suggest the conclusion about mutual mitigation of the effects of nanoparticles and the mycotoxin on rats blood and liver cells after AfB(1) has adsorbed on MND.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Mogilnaya, Olga, Ronzhin, Nikita, Artemenko, Karina, Bondar, Vladimir
Заглавие : Nanodiamonds as an effective adsorbent for immobilization of extracellular peroxidases from luminous fungus Neonothopanus nambi to construct a phenol detection system
Колич.характеристики :9 с
Коллективы : Russian Academy of Sciences [0356-2016-0709]
Место публикации : Biocatal. Biotransform.: TAYLOR & FRANCIS LTD, 2019. - Vol. 37, Is. 2. - С. 97-105. - ISSN 1024-2422, DOI 10.1080/10242422.2018.1472586. - ISSN 1029-2446(eISSN)
Примечания : Cited References:50. - This work was supported by the state budget allocated to the fundamental research at the Russian Academy of Sciences [project no. 0356-2016-0709].
Предметные рубрики: CARBON NANOTUBES
ARMILLARIA-BOREALIS
LIGHT-EMISSION
DEGRADATION
Ключевые слова (''Своб.индексиров.''): nanodiamonds--immobilization--luminous fungus--beta-glucosidase--peroxidase--indicator system
Аннотация: Modified nanodiamonds (MNDs) produced by detonation synthesis can be used as an effective adsorbent to immobilize extracellular peroxidases of the luminous basidiomycete Neonothopanus nambi. The enzymes are firmly immobilized on MND particles and exhibit catalytic activity. The indicator system (the MND-enzyme complex) reused many times retains its ability to catalyze reaction of co-oxidation of phenol and 4-aminoantipirine in the presence of hydrogen peroxide and remains functionally active during long-term storage (for 1 month or longer) in aqueous suspensions at 4 degrees C. MNDs and enzymes of higher fungi can be effectively used to construct new reusable indicator systems for analytical applications such as monitoring contamination of aquatic environments by phenolic compounds.
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