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The influence of food concentration and "water of aggregation" on the reproductive parameters of Moina macrocopa (Crustacea: Cladocera) females / E. S. Zadereev, V. G. Gubanov, I. V. Egorov // Zhurnal Obshchei Biologii. - 1998. - Vol. 59, Is. 1. - С. 55-57 . - ISSN 0044-4596
Аннотация: Combined influence of "water of aggregation" and food concentration on the reproductive parameters of Moina macrocopa females was investigated. In all experiments the influence of population density was associated with the effect of "water of aggregation" prepared earlier by keeping dense population (200 ?g/ml) of M. macrocopa. It was shown that life-span of M. macrocopa females in "water of aggregation" was not dependent on food concentration; under conditions of all tested food concentration it was less than in case of control clean water. There was no difference in proportion of males produced in "water of aggregation" and in control though more males were born under conditions of higher food concentration. In general "water of aggregation" causes a specific acceleration of female life history: the life-span and the period between clutches decrease, the amount of neonates in last clutches increases while the chance of male production at the beginning of reproduction period becames greater. The "water of aggregation" could also causes the formation of ephipial eggs instead of the first partenogenetic clutch. It seems that life strategy under conditions of very high mortality associated with "water of aggregation" is aimed to maximum realization of individual capacities in short period of time.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Branch, Russian Academy of Science, Akademgorodok, Krasnoyarsk 660036, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Zadereev, E.S.; Gubanov, V.G.; Egorov, I.V.

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Bioluminescent analysis of intensity of pathological oxidative processes in cells of perfused rat liver after hyperthermia / N. N. Remmel [et al.] // Bulletin of Experimental Biology and Medicine. - 2003. - Vol. 135, Is. 1. - P. 43-45, DOI 10.1023/A:1023489727703 . - ISSN 0007-4888
Кл.слова (ненормированные):
Bioluminescent analysis -- Controlled perfusion of isolated liver -- Hyperthermia oxidative stress -- thiobarbituric acid reactive substance -- animal experiment -- animal model -- animal tissue -- article -- bioluminescence -- concentration (parameters) -- controlled study -- correlation analysis -- female -- hyperthermia -- in vivo study -- lipid peroxidation -- liver metabolism -- liver perfusion -- male -- nonhuman -- oxidative stress -- oxygen consumption -- pathology -- rat -- thermal exposure -- Animals -- Female -- Hepatocytes -- Hyperthermia, Induced -- Liver -- Luminescent Measurements -- Male -- Oxidative Stress -- Perfusion -- Rats -- Animalia
Аннотация: We studied the possibility of evaluation of the intensity of pathological oxidative processes in rat liver using an integral bioluminescent test with controlled perfusion of the isolated organ. The test revealed a significant correlation between the level of TBA-reactive products and bioluminescence intensity.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Division, Russian Academy of Sciences, Novosibirsk, Russian Federation
Krasnoyarsk State University, Krasnoyarsk, Russian Federation
Intl. Res. Ctr. of Extreme States, Siberian Division, Russian Academy of Sciences, Novosibirsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Remmel, N.N.; Kratasyuk, V.A.; Maznyak, O.M.; Inzhevatkin, E.V.; Nefedov, V.P.

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Dobutamine prevents experimental postintoxication liver cirrhosis in mice / A. P. Vinokurov, A. V. Eremeev, N. A. Setkov // Bulletin of Experimental Biology and Medicine. - 2002. - Vol. 134, Is. 1. - P. 43-46, DOI 10.1023/A:1020604621142 . - ISSN 0007-4888
Кл.слова (ненормированные):
Dobutamine -- Hepatocytes -- Liver cirrhosis -- Proliferation -- adrenergic receptor stimulating agent -- alpha 1 adrenergic receptor stimulating agent -- beta 1 adrenergic receptor stimulating agent -- beta 2 adrenergic receptor stimulating agent -- carbon tetrachloride -- catecholamine derivative -- dobutamine -- epidermal growth factor -- animal cell -- animal experiment -- animal model -- animal tissue -- article -- cell activity -- cell culture -- cell death -- cell proliferation -- cell stimulation -- chronic hepatitis -- connective tissue -- controlled study -- disease association -- drug effect -- drug potency -- experimental test -- female -- liver cell -- liver cirrhosis -- liver fibrosis -- liver hyperplasia -- liver necrosis -- liver parenchyma -- liver regeneration -- liver toxicity -- morphology -- mouse -- nonhuman -- toxicity testing -- Adrenergic beta-Agonists -- Animals -- Carbon Tetrachloride -- Cell Division -- Dobutamine -- Dose-Response Relationship, Drug -- Female -- Hepatocytes -- Liver -- Liver Cirrhosis -- Mice -- Mice, Inbred BALB C -- Animalia
Аннотация: Various chronic inflammatory and necrotic processes in the liver parenchyma are accompanied by pathological morphofunctional changes, which are associated with hepatocyte death and hyperplasia of the connective tissue. Regeneration of the liver parenchyma should include not only prevention of fibrosis, but also stimulation of hepatocyte prolifearation. The adrenoceptor agonist dobutamine stimulated proliferative activity of cultured hepatocytes and prevented the development of postintoxication liver cirrhosis in mice produced by chronic poisoning with CCl4.

Scopus
Держатели документа:
Department of General Surgery, Krasnoyarsk State Medical Academy, Krasnoyarsk, Russian Federation
Institute of Biophysics, Siberian Division, Russian Academy of Sciences, Krasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Vinokurov, A.P.; Eremeev, A.V.; Setkov, N.A.

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Comparison of seasonal dynamics of the essential PUFA contents in benthic invertebrates and grayling Thymallus arcticus in the Yenisei river / N. N. Sushchik [et al.] // Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. - 2006. - Vol. 145, Is. 3-4. - P278-287, DOI 10.1016/j.cbpb.2006.05.014 . - ISSN 1096-4959
Кл.слова (ненормированные):
Benthic invertebrates -- Grayling -- Polyunsaturated fatty acids -- Riverine food web -- essential fatty acid -- long chain fatty acid -- polyunsaturated fatty acid -- Amphipoda -- animal tissue -- annelid worm -- article -- benthos -- Chironomidae -- comparative study -- controlled study -- dominant inheritance -- ecosystem -- evolution -- fatty acid analysis -- female -- fish -- fly -- invertebrate -- larva -- male -- metabolic regulation -- nonhuman -- nutrient dynamics -- priority journal -- river -- seasonal variation -- statistical significance -- Thymallus arcticus -- Animals -- Fatty Acids, Unsaturated -- Food Chain -- Gastrointestinal Contents -- Invertebrates -- Muscles -- Rivers -- Russia -- Salmonidae -- Seasons -- Amphipoda -- Chironomidae -- Diptera -- Gammaridae -- Invertebrata -- Oligochaeta (Metazoa) -- Thymallus arcticus -- Trichoptera
Аннотация: Seasonal dynamics of contents of essential polyunsaturated fatty acids (PUFA) in dominant groups of benthic invertebrates: gammarids (Gammaridae, Amphipoda), oligochaetes (Oligochaeta), chironomid larvae (Chironomidae, Diptera) and caddisfly larvae (Trichoptera), and dominant benthivorous fish, Siberian grayling Thymallus arcticus, have been studied in ecosystem of the large Siberian river. During the year of the study most benthic invertebrate taxa showed significant variations in the contents of both C-18 and long chain C-20-22 PUFAs. In contrast, the fish, which consumed the zoobenthos, had no significant seasonal variations in long chain PUFAs' contents. Thereby, the fish, as organisms of relatively higher evolution level than invertebrates, was supposed to have more strict metabolic control of long chain PUFAs' contents. Evidence was obtained that the studied fish species, grayling, may be capable to convert dietary EPA into DHA. В© 2006 Elsevier Inc. All rights reserved.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Branch, Russian Academy of Science, Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Krasnoyarsk State University, Svobodny av. 79, Krasnoyarsk, 660041, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Sushchik, N.N.; Gladyshev, M.I.; Kalachova, G.S.; Makhutova, O.N.; Ageev, A.V.

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Effect of methyl farnesoate on the change of the reproduction mode in Moina macrocopa (Cladocera) / E. N. Volkova, E. S. Zadereev // Doklady Biochemistry and Biophysics. - 2012. - Vol. 447, Is. 1. - P282-285, DOI 10.1134/S1607672912050158 . - ISSN 1607-6729
Кл.слова (ненормированные):
farnesoic acid methyl ester -- unsaturated fatty acid -- animal -- article -- Cladocera -- drug effect -- female -- parthenogenesis -- physiology -- reproduction -- Animals -- Cladocera -- Fatty Acids, Unsaturated -- Female -- Parthenogenesis -- Reproduction

Scopus
Держатели документа:
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, 660041, Russian Federation
Institute of Biophysics, Siberian Branch, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Volkova, E.N.; Zadereev, E.S.

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Role of diapause in coexistence of zooplankton species: Model analysis / E. S. Zadereev, I. G. Prokopkin // Doklady Biological Sciences. - 2007. - Vol. 412, Is. 1. - P73-75, DOI 10.1134/S0012496607010243 . - ISSN 0012-4966
Кл.слова (ненормированные):
animal -- article -- biological model -- Cladocera -- ecosystem -- female -- growth, development and aging -- oocyte -- physiology -- population dynamics -- reproduction -- zooplankton -- Animals -- Cladocera -- Ecosystem -- Female -- Models, Biological -- Ovum -- Population Dynamics -- Reproduction -- Zooplankton

Scopus
Держатели документа:
Institute of Biophysics, Siberian Division, Russian Academy of Sciences, Krasnoyarsk, 660036, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Zadereev, E.S.; Prokopkin, I.G.

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The influence of food concentration and "water aggregation" on the reproductive parameters of Moina macrocopa (Crustacea : Cladocera) females [Текст] / E. S. Zadereev, V. G. Gubanov, I. V. Egorov // Zhurnal Obshchei Biol. - 1998. - Vol. 59, Is. 1. - P. 45-57. - Cited References: 27 . - ISSN 0044-4596

РУБ Biology
Рубрики:
DAPHNIA-MAGNA
   EGG SIZE
   DENSITY
   POPULATION
   INDUCTION
   PULEX
Аннотация: Combined influence of "water of aggregation" and food concentration on the reproductive parameters of Moina macrocopa females was investigated. In all experiments the influence of population density was associated with the effect of "water of aggregation" prepared earlier by keeping dense population (200 mu g/ml) of M. macrocopa. It was shown that life-span of M. macrocopa females in "water of aggregation" was not dependent on food concentration; under conditions of all tested food concentration it was less than in case of control clean water. There was no difference in proportion of males produced in "water of aggregation" and in control though more males were born under conditions of higher food concentration. In general "water of aggregation" causes a specific acceleration of female life history: the life-span and the period between clutches decrease, the amount of neonates in last clutches increases while the chance of male production at the beginning of reproduction period becames greater. The "water of aggregation" could also causes the formation of ephipial eggs instead of the first partenogenetic clutch. It seems that life strategy under conditions of very high mortality associated with "water of aggregation" is aimed to maximum realization of individual capacities in short period of time.

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Держатели документа:
Russian Acad Sci, Inst Biophys, Siberian Branch, Krasnoyarsk 660036, Russia
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Zadereev, E.S.; Gubanov, V.G.; Egorov, I.V.

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Study of the immunogenicity of the VP2 protein of canine parvovirus produced using an improved Baculovirus expression system / D. Chang, Y. Liu, Y. Chen [et al.] // BMC Vet. Res. - 2020. - Vol. 16, Is. 1. - Ст. 202, DOI 10.1186/s12917-020-02422-3 . - ISSN 1746-6148
Кл.слова (ненормированные):
Baculovirus expression system -- Canine parvovirus -- VP2 protein -- canine parvovirus vaccine -- protein VP2 -- recombinant protein -- unclassified drug -- virus antibody -- virus vaccine -- affinity chromatography -- animal experiment -- antibody titer -- Article -- baculovirus expression system -- Canine parvovirus -- controlled study -- DNA transposition -- enzyme linked immunosorbent assay -- female -- fluorescence microscopy -- gene expression level -- hemagglutination inhibition -- hemagglutination inhibition test -- immunogenicity -- mouse -- nonhuman -- parvovirus infection -- protein expression -- Sf9 cell line -- vaccination -- Western blotting
Аннотация: Background: Canine parvovirus (CPV) is now recognized as a serious threat to the dog breeding industry worldwide. Currently used CPV vaccines all have their specific drawbacks, prompting a search for alternative safe and effective vaccination strategies such as subunit vaccine. VP2 protein is the major antigen targeted for developing CPV subunit vaccine, however, its production in baculovirus expression system remains challenging due to the insufficient yield. Therefore, our study aims to increase the VP2 protein production by using an improved baculovirus expression system and to evaluate the immunogenicity of the purified VP2 protein in mice. Results: The results showed that high-level expression of the full length VP2 protein was achieved using our modified baculovirus expression system. The recombinant virus carrying two copies of VP2 gene showed the highest expression level, with a productivity of 186 mg/L, which is about 1.4-1.6 fold that of the recombinant viruses carrying only one copy. The purified protein reacted with Mouse anti-His tag monoclonal antibody and Rabbit anti-VP2 polyclonal antibody. BALB/c mice were intramuscularly immunized with purified VP2 protein twice at 2 week intervals. After vaccination, VP2 protein could induce the mice produce high level of hemagglutination inhibition antibodies. Conclusions: Full length CPV VP2 protein was expressed at high level and purified efficiently. Moreover, it stimulated mice to produce high level of antibodies with hemmaglutination inhibition properties. The VP2 protein expressed in this study could be used as a putative economic and efficient subunit vaccine against CPV infection. © 2020 The Author(s).

Scopus
Держатели документа:
Henan Provincal Engineering and Technology Center of Health Products for Livestock and Poultry, Key Laboratory of Ecological Security, Collab. Innov. Ctr. of Water Secty. for Water Src. Reg. of Mid-line of S.-to-N. Diversion Proj. of Henan Prov., School of Agricultural Engineering, Nanyang Normal University, Nanyang, 473061, China
Institute of Biophysics, Siberian Branch, Russian Academy of Science, Federal Research Center Krasnoyarsk Science Center SB RAS, Krasnoyarsk, 660036, Russian Federation

Доп.точки доступа:
Chang, D.; Liu, Y.; Chen, Y.; Hu, X.; Burov, A.; Puzyr, A.; Bondar, V.; Yao, L.

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Fatty acid content and composition in tissues of Baikal grayling (Thymallus baicalensis), with a special focus on DHA synthesis / O. N. Makhutova, K. N. Stoyanov // Aquac. Int. - 2021, DOI 10.1007/s10499-021-00755-w . - Article in press. - ISSN 0967-6120
Кл.слова (ненормированные):
Aquaculture -- Docosahexaenoic fatty acid -- Fish diet -- Furan fatty acids -- Sprecher pathway
Аннотация: Long-chain polyunsaturated fatty acids of n-3 family (n-3 LC PUFAs) are physiologically essential compounds required for normal growth and development of animals, including humans. The ability of fish species to synthesize n-3 LC PUFAs varies significantly across different trophic levels. We have studied fatty acid (FA) content (mg/g of wet weight) and level (% of total FAs) in the brain, liver, heart, intestine, female and male gonads, muscle, and adipose tissues of commercially important wild freshwater Baikal grayling. Additionally, FA content and level of Baikal grayling juveniles have been studied. In all tissues of Baikal grayling, some LC PUFAs, namely, 24:5n-3 and 24:6n-3 (C24 PUFAs), have been found. These FAs are the intermediate products in the synthesis of docosahexaenoic acid (DHA, 22:6n-3) by the Sprecher pathway. The levels of C24 PUFAs in tissues differed significantly: the highest levels of C24 PUFAs were found in adipose tissue and the lowest values in the gonads of females, liver, brain, and head of juveniles. According to the dynamics of DHA and C24 PUFAs, the maximum rate of DHA synthesis is achieved in brain of Baikal grayling, while the lowest rate of DHA synthesis probably occurs in adipose tissue. Although all studied tissues had differences in the number of FAs and their levels, 16:0, 18:1n-9, 16:1n-7, 20:5n-3, and DHA dominated. Male gonads contained an extremely high level of furan FAs — presumably beneficial substances for human health. Additionally, the nutritional value of the tissues of Baikal grayling as a source of n-3 LC PUFAs for humans has been estimated. © 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Scopus
Держатели документа:
Institute of Biophysics of Federal Research Center “Krasnoyarsk Science Center” of Siberian Branch of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Siberian Federal University, 79 Svobodny pr, Krasnoyarsk, 660041, Russian Federation

Доп.точки доступа:
Makhutova, O. N.; Stoyanov, K. N.

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10.

Fatty acid content and composition in tissues of Baikal grayling (Thymallus baicalensis), with a special focus on DHA synthesis / O. N. Makhutova, K. N. Stoyanov // Aquac. Int. - 2021, DOI 10.1007/s10499-021-00755-w. - Cited References:75. - The research was funded by a grant from the Russian Foundation for Basic Research (RFBR) N 20-04-00594, by the state assignment within the framework of the Basic Research Program of the Russian Federation (topic no. 51.1.1) and the state assignment of the Ministry of Science and Higher Education of the Russian Federation to Siberian Federal University in 2020 (Project no. FSRZ-2020-0006 "Biologically active substances in environmental, biotechnological and medical systems"). . - Article in press. - ISSN 0967-6120. - ISSN 1573-143X

РУБ Fisheries
Рубрики:
COD GADUS-MORHUA
   DOCOSAHEXAENOIC ACID
   SEASONAL DYNAMICS
   FISH
Кл.слова (ненормированные):
Docosahexaenoic fatty acid -- Sprecher pathway -- Fish diet -- Furan fatty -- acids -- Aquaculture
Аннотация: Long-chain polyunsaturated fatty acids of n-3 family (n-3 LC PUFAs) are physiologically essential compounds required for normal growth and development of animals, including humans. The ability of fish species to synthesize n-3 LC PUFAs varies significantly across different trophic levels. We have studied fatty acid (FA) content (mg/g of wet weight) and level (% of total FAs) in the brain, liver, heart, intestine, female and male gonads, muscle, and adipose tissues of commercially important wild freshwater Baikal grayling. Additionally, FA content and level of Baikal grayling juveniles have been studied. In all tissues of Baikal grayling, some LC PUFAs, namely, 24:5n-3 and 24:6n-3 (C24 PUFAs), have been found. These FAs are the intermediate products in the synthesis of docosahexaenoic acid (DHA, 22:6n-3) by the Sprecher pathway. The levels of C24 PUFAs in tissues differed significantly: the highest levels of C24 PUFAs were found in adipose tissue and the lowest values in the gonads of females, liver, brain, and head of juveniles. According to the dynamics of DHA and C24 PUFAs, the maximum rate of DHA synthesis is achieved in brain of Baikal grayling, while the lowest rate of DHA synthesis probably occurs in adipose tissue. Although all studied tissues had differences in the number of FAs and their levels, 16:0, 18:1n-9, 16:1n-7, 20:5n-3, and DHA dominated. Male gonads contained an extremely high level of furan FAs - presumably beneficial substances for human health. Additionally, the nutritional value of the tissues of Baikal grayling as a source of n-3 LC PUFAs for humans has been estimated.

WOS
Держатели документа:
Russian Acad Sci Akademgorodok, Siberian Branch, Inst Biophys, Fed Res Ctr,Krasnoyarsk Sci Ctr, Krasnoyarsk 660036, Russia.
Siberian Fed Univ, 79 Svobodny Pr, Krasnoyarsk 660041, Russia.

Доп.точки доступа:
Makhutova, Olesia N.; Stoyanov, Kirill N.; Russian Foundation for Basic Research (RFBR)Russian Foundation for Basic Research (RFBR) [20-04-00594]; Russian FederationRussian Federation [51.1.1]; Ministry of Science and Higher Education of the Russian Federation [FSRZ-2020-0006]

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11.

Gamma irradiation of resting eggs of Moina macrocopa affects individual and population performance of hatchlings / E. Zadereev [et al.] // J. Environ. Radioact. - 2017. - Vol. 175-176. - P126-134, DOI 10.1016/j.jenvrad.2017.05.002 . - ISSN 0265-931X
Кл.слова (ненормированные):
Cladocera -- Life cycle parameters -- Population performance -- Resting eggs -- ?-radiation -- Gamma rays -- Irradiation -- Life cycle -- Radiation effects -- Radioactive materials -- Sediments -- Cladocera -- Cycle parameters -- Dose response relationships -- Population performance -- Reproductive rates -- Resting eggs -- Sensitive parameter -- Zooplankton communities -- Radiation -- adolescent -- Cladocera -- contamination -- controlled study -- dose response -- female -- gamma irradiation -- gamma radiation -- hatchling -- human -- human experiment -- life cycle -- Moina macrocopa -- newborn -- nonhuman -- sediment -- zooplankton -- Animalia -- Cladocera -- Moina macrocopa
Аннотация: We investigated the effects of ?-radiation on the survival of resting eggs of the cladoceran Moina macrocopa, on the parameters of the life cycle of neonates hatched from the irradiated eggs and on the performance of the population initiated from irradiated eggs. The study showed that ?-radiation in a range of doses from the background level to 100 Gy had no effect on survival of irradiated eggs. The absorbed dose of 200 Gy was lethal to resting eggs of M. macrocopa. The number of clutches and net reproductive rate (R0) of hatchlings from eggs exposed to radiation were the strongly affected parameters in experiments with individual females. The number of clutches per female was drastically reduced for females hatched from egg exposed to 80–100 Gy. The most sensitive parameter was the R0. The estimated ED50 for the R0 (effective dose that induces 50% R0 reduction) was 50 Gy. Population performance was also affected by the irradiation of the resting stage of animals that initiated population. Populations that was initiated from hatchlings from resting eggs exposed to 100 Gy was of smaller size and with fewer juvenile and parthenogenetic females in comparison with control populations. Thus, we determined the dose-response relationship for the effect of gamma radiation on survival of resting eggs and individual and population responses of hatchlings from irradiated resting eggs. We conclude that for highly polluted areas contamination of bottom sediments with radioactive materials could affect zooplankton communities through adverse chronic effects on resting eggs, which will be transmitted to hatchlings at individual or population levels. © 2017 Elsevier Ltd

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Держатели документа:
Institute of Biophysics, Federal Research Centre Krasnoyarsk Scientific Centre, Siberian Branch, Russian Academy of Sciences, 50/50 Akademgorodok, Krasnoyarsk, Russian Federation
Siberian Federal University, 79 Svobodniy Ave., Krasnoyarsk, Russian Federation
Budker Institute of Nuclear Physics, 11 Akademika Lavrent'eva Ave., Novosibirsk, Russian Federation

Доп.точки доступа:
Zadereev, E.; Lopatina, T.; Oskina, N.; Zotina, T.; Petrichenkov, M.; Dementyev, D.

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12.

Ecological Forms of Black Sea Brown Trout (Salmo trutta labrax) in the Mzymta River as Manifestation of Ontogenetic Plasticity / A. A. Makhrov [et al.] // Russ. J. Dev. Biol. - 2018. - Vol. 49, Is. 2. - P117-127, DOI 10.1134/S1062360418020054. - Cited References:77. - This study was supported by the Russian Scientific Foundation, project no. 16-14-10001. . - ISSN 1062-3604. - ISSN 1608-3326

РУБ Developmental Biology
Рубрики:
ATLANTIC SALMON
   POPULATIONS
   HISTORY
   L.
   MIGRATION
   SURVIVAL
Кл.слова (ненормированные):
Salmonidae -- brown trout -- trout -- ontogenesis -- migrations -- maturation -- phenotypic plasticity -- gonads -- smolts
Аннотация: Populations of brown trout in the Mzymta River and its tributaries include anadromous (mainly female) and resident (mainly males) fish. Some resident males in the basin of the Mzymty River attain sexual maturity at the age 1+, and resident females mature at the age 2+ or 3+. The maximum age of resident fish is 4+ in the samples studied. Migrations of anadromous brown trout to the sea occur at the ages 1+, 2+, or 3+. Future spawners spend from 1 to 4 years at feeding grounds in the sea. Smolts of the population are characterized by performing not only spring but also autumn migrations to the sea. One smolt specimen has been detected upstream from the dam in the river where spawners of anadromous brown trout do not migrate; this means that the capability for sea migrations persists long in the population represented only by resident specimens of brown trout. The diversity of life cycles and ecological forms in populations of brown trout is not lower than in populations of brown trout in Northern and Western Europe. The comparison of the data obtained with published data makes it possible to come to the conclusion about the high plasticity of ontogenesis of Black Sea brown trout.

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Держатели документа:
Russian Acad Sci, Severtsov Inst Ecol & Evolut, Moscow 119071, Russia.
Russian Acad Sci, Fed Res Ctr Krasnoyarsk Sci Ctr, Inst Biophys, Siberian Branch, Krasnoyarsk 660036, Russia.
St Petersburg State Univ, St Petersburg 199034, Russia.
Azov Res Inst Fisheries, Krasnodar Branch, Krasnodar 350000, Russia.
Moscow MV Lomonosov State Univ, Moscow 119991, Russia.
Kuban State Univ, Krasnodar 350040, Russia.

Доп.точки доступа:
Makhrov, A. A.; Artamonova, V. S.; Murza, I. G.; Pashkov, A. N.; Ponomareva, M. V.; Reshetnikov, S. I.; Christoforov, O. L.; Russian Scientific Foundation [16-14-10001]

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13.

Biotechnological wound dressings based on bacterial cellulose and degradable copolymer P(3HB/4HB) / T. G. Volova [et al.] // Int. J. Biol. Macromol. - 2019. - Vol. 131. - P230-240, DOI 10.1016/j.ijbiomac.2019.03.068. - Cited By :1 . - ISSN 0141-8130
Кл.слова (ненормированные):
Bacterial cellulose -- Composites -- Polyhydroxyalkanoates -- 3 hydroxybutyric acid 4 hydroxybutyric acid copolymer -- actovegin -- bacterial cellulose -- cellulose -- collagen type 1 -- copolymer -- cytokeratin 10 -- cytokeratin 14 -- solcoseryl -- unclassified drug -- angiogenesis -- animal cell -- animal experiment -- animal model -- animal tissue -- biochemical analysis -- biocompatibility -- burn -- cell growth -- controlled study -- cutaneous parameters -- differential scanning calorimetry -- drug release -- elemental analysis -- female -- fibroblast -- histopathology -- in vitro study -- in vivo study -- inflammation -- mechanics -- nonhuman -- rat -- Review -- wound healing -- wound planimetry -- X ray analysis
Аннотация: Hybrid wound dressings have been constructed using two biomaterials: bacterial cellulose (BC) and copolymer of 3-hydroxybutyric and 4-hydroxybutyric acids [P(3HB/4HB)] – a biodegradable polymer of microbial origin. Some of the experimental membranes were loaded with drugs promoting wound healing and epidermal cells differentiated from multipotent adipose-derived mesenchymal stem cells. A study has been carried out to investigate the structure and physical/mechanical properties of the membranes. The in vitro study showed that the most effective scaffolds for growing fibroblasts were composite BC/P(3HB/4HB) films loaded with actovegin. Two types of the experimental biotechnological wound dressings – BC/P(3HB/4HB)/actovegin and BC/P(3HB/4HB)/fibroblasts – were tested in vivo, on laboratory animals with model third-degree skin burns. Wound planimetry, histological examination, and biochemical and molecular methods of detecting factors of angiogenesis, inflammation, type I collagen, and keratin 10 and 14 were used to monitor wound healing. Experimental wound dressings promoted healing more effectively than VoskoPran – a commercial wound dressing. © 2019

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Держатели документа:
Siberian Federal University, 79 Svobodnyi Av., Krasnoyarsk, 660041, Russian Federation
Institute of Biophysics of Siberian Branch of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036, Russian Federation
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, 1 Partizan Zheleznyak Street, Krasnoyarsk, 660022, Russian Federation

Доп.точки доступа:
Volova, T. G.; Shumilova, A. A.; Nikolaeva, E. D.; Kirichenko, A. K.; Shishatskaya, E. I.

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14.

Differences in fatty acid composition between smolts of Sockeye Salmon and adults migrated from sea to lake for spawning / M. I. Gladyshev [et al.] // Doklady Biochemistry and Biophysics. - 2010. - Vol. 430, Is. 1. - P29-32, DOI 10.1134/S1607672910010096 . - ISSN 1607-6729
Кл.слова (ненормированные):
fatty acid -- fresh water -- sea water -- animal -- article -- chemistry -- cytology -- female -- male -- metabolism -- muscle -- physiology -- population migration -- reproduction -- salmon -- sea -- Animal Migration -- Animals -- Fatty Acids -- Female -- Fresh Water -- Male -- Muscles -- Oceans and Seas -- Reproduction -- Salmon -- Seawater -- Oncorhynchus nerka

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Держатели документа:
Institute of Biophysics, Siberian Branch, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036, Russian Federation
Kamchatka Research Institute of Fisheries and Oceanography, Naberezhnaya 18, Petropavlovsk-Kamchatskii, 683602, Russian Federation
Siberian Federal University, Krasnoyarsk, 660041, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Gladyshev, M.I.; Lepskaya, E.V.; Sushchik, N.N.; Makhutova, O.N.; Kalacheva, G.S.

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15.

Tissue response to biodegradable suture threads made of polyhydroxyalkanoates / E. I. Shishatskaya [et al.] // Biomedical Engineering. - 2002. - Vol. 36, Is. 4. - P210-217, DOI 10.1023/A:1021184119268 . - ISSN 0006-3398
Кл.слова (ненормированные):
acid phosphatase -- alkaline phosphatase -- polyhydroxyalkanoic acid -- animal experiment -- animal tissue -- article -- biocompatibility -- biodegradability -- controlled study -- elasticity -- enzyme activity -- enzyme mechanism -- female -- histochemistry -- incision -- nonhuman -- physical chemistry -- postoperative period -- rat -- rigidity -- suture -- thickness -- tissue reaction -- wound healing -- Animalia

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Держатели документа:
Institute of Biophysics, Russian Academy of Sciences, Krasnoyarsk Terr. Bur. Pathol. Anat., Krasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Shishatskaya, E.I.; Volova, T.G.; Efremov, S.N.; Puzyr', A.P.; Mogil'Naya, O.A.

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16.

Study of biological properties of polyhydroxyalkanoates in a long-term experiment in vivo / E. I. Shishatskaya, T. G. Volova, T. G. Popova // Biomedical Engineering. - 2002. - Vol. 36, Is. 4. - P218-222, DOI 10.1023/A:1021136203338 . - ISSN 0006-3398
Кл.слова (ненормированные):
hemoglobin -- polyhydroxyalkanoic acid -- animal experiment -- animal tissue -- article -- biocompatibility -- biodegradability -- biosynthesis -- blood cell count -- blood sampling -- comparative study -- controlled study -- DNA synthesis -- elasticity -- enzyme activity -- enzyme mechanism -- erythrocyte sedimentation rate -- female -- in vivo study -- liver function -- nonhuman -- organ weight -- rat -- suture -- Animalia

Scopus
Держатели документа:
Institute of Biophysics, Russian Academy of Sciences, Institute of Computer Simulation, Krasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Shishatskaya, E.I.; Volova, T.G.; Popova, T.G.

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17.

In vivo toxicological evaluation of polyhydroxyalkanoates. / E. I. Shishatskaya, T. G. Volova, I. I. Gitelson // Doklady Biological Sciences. - 2002. - Vol. 383, Is. 1-6. - P109-111 . - ISSN 0012-4966
Кл.слова (ненормированные):
alkane -- animal -- animal behavior -- article -- cytology -- drug effect -- erythrocyte sedimentation rate -- female -- heart -- kidney -- liver -- lymphoid tissue -- male -- rat -- spleen -- Wistar rat -- Alkanes -- Animals -- Behavior, Animal -- Blood Sedimentation -- Female -- Heart -- Kidney -- Liver -- Lymphoid Tissue -- Male -- Rats -- Rats, Wistar -- Spleen

Scopus
Держатели документа:
Institute of Biophysics, Siberian Division, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036 Russia. : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Shishatskaya, E.I.; Volova, T.G.; Gitelson, I.I.

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18.

Distribution and resorption of polymeric microparticles in visceral organs of laboratory animals after intravenous injection / E. I. Shishatskaya [et al.] // Bulletin of Experimental Biology and Medicine. - 2009. - Vol. 148, Is. 5. - P789-793, DOI 10.1007/s10517-010-0817-3 . - ISSN 0007-4888
Кл.слова (ненормированные):
14C -- Intravenous injection -- Microparticles -- Resorbable polyhydroxybutyrate -- Visceral tissues -- carbon 14 -- microsphere -- polyhydroxyaminobutyric acid -- polymer -- unclassified drug -- animal experiment -- animal tissue -- article -- biocompatibility -- biodegradability -- body growth -- controlled drug release -- controlled study -- degradation kinetics -- drug delivery system -- drug dosage form -- experimental animal -- female -- liver parenchyma -- molecular weight -- nonhuman -- particle size -- physical development -- radioactivity -- rat -- spleen -- tissue distribution -- tissue structure -- Animals -- Animals, Laboratory -- Carbon Radioisotopes -- Female -- Injections, Intravenous -- Particle Size -- Polymers -- Rats -- Rats, Wistar -- Tissue Distribution -- Viscera -- Animalia
Аннотация: Microparticles obtained by using 14C-labeled resorbable hydroxyaminobutyric acid polymer were injected into the caudal vein of laboratory animals without negative aftereffects for their growth and development and without changes in the macro- and microstructure of organs and tissues. The distribution of microparticles in the viscera and the dynamics of accumulation of carbon-containing polymer degradation products in the viscera were studied. The main targets for the particles are liver tissues, as well as renal and splenic tissues. The polymeric matrix of the microparticles is most actively destroyed in the spleen and liver. The presence of high-molecular- weight polymeric matrix in organs indicates the integrity of microparticles and the possibility of long-term (up to 12 weeks) functioning of polymeric particles in vivo. В© 2009 Springer Science+Business Media, Inc.

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Держатели документа:
Institute of Biophysics, Siberian Division of Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Institute of Basic Biology and Biotechnology, Siberian Federal University, Krasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Shishatskaya, E.I.; Goreva, A.V.; Voinova, O.N.; Kalacheva, G.S.; Volova, T.G.

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19.

Tissue reaction to intramuscular injection of resorbable polymer microparticles / E. I. Shishatskaya [et al.] // Bulletin of Experimental Biology and Medicine. - 2007. - Vol. 144, Is. 6. - P786-790, DOI 10.1007/s10517-007-0432-0 . - ISSN 0007-4888
Кл.слова (ненормированные):
Microencapsulation -- Polyhydroxybutyrate -- Resorbable polymers -- Tissue reaction -- poly(3 hydroxybutyric acid) -- polymer -- animal experiment -- animal tissue -- article -- cell infiltration -- controlled study -- drug delivery system -- drug formulation -- female -- giant cell -- inflammation -- macrophage -- microencapsulation -- nonhuman -- rat -- tissue reaction -- Absorbable Implants -- Animals -- Drug Compounding -- Female -- Foreign-Body Reaction -- Injections, Intramuscular -- Microspheres -- Polyesters -- Rats -- Rats, Wistar
Аннотация: Tissue reaction to implantation of polymeric microparticles from resorbable polymer (polyhydroxybutyrate) is characterized by slight inflammatory reaction and pronounced progressive macrophage infiltration with the presence of mono-and multinuclear foreign body giant cells resorbing the polymeric matrix. No fibrous capsules were formed around the polymeric microparticles; neither necrosis nor other adverse morphological changes and tissue transformation in response to implantation of the PHB microparticles were recorded. The results indicate good prospects of using polyhydroxybutyrate for the construction of long-acting dosage forms as microparticles for intramuscular injection. В© Springer Science+Business Media, Inc. 2007.

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Держатели документа:
Institute of Biophysics, Siberian Division of Russian Academy of Sciences, Krasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Shishatskaya, E.I.; Voinova, O.N.; Goreva, A.V.; Mogilnaya, O.A.; Volova, T.G.

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20.

Tissue response to the implantation of biodegradable polyhydroxyalkanoate sutures / E. I. Shishatskaya [et al.] // Journal of Materials Science: Materials in Medicine. - 2004. - Vol. 15, Is. 6. - P719-728, DOI 10.1023/B:JMSM.0000030215.49991.0d . - ISSN 0957-4530
Кл.слова (ненормированные):
Necrosis -- Polymeric implants -- Suppurative inflammation -- Tissue reaction -- Biodegradation -- Calcification (biochemistry) -- Cells -- Copolymers -- Implants (surgical) -- Silk -- Tissue -- Tumors -- Materials science -- acid phosphatase -- copolymer -- poly(3 hydroxybutyric acid) -- polyhydroxyalkanoic acid -- polyhydroxyvaleric acid -- unclassified drug -- animal experiment -- animal model -- article -- biodegradable implant -- blood vessel reactivity -- catgut -- controlled study -- enzyme activity -- female -- giant cell -- histochemistry -- inflammation -- macrophage -- nonhuman -- priority journal -- rat -- silk -- suture -- tensile strength -- tissue reaction -- tissue structure -- wound healing -- young modulus -- Absorbable Implants -- Animals -- Female -- Fibrosis -- Foreign-Body Reaction -- Hydroxybutyrates -- Muscle, Skeletal -- Polyesters -- Polymers -- Rats -- Rats, Wistar -- Sutures -- Treatment Outcome -- Wounds, Penetrating -- Animalia
Аннотация: Polyhydroxyalkanoate (PHA) sutures were implanted to test animals intramuscularly, and tissue reaction was investigated and compared with the reaction to silk and catgut. Tested monofilament sutures made of PHAs of two types polyhydroxybutyrate (PHB) and a copolymer of hydroxybutyrate and hydroxyvalerate (PHV) featured the strength necessary for the healing of muscle-fascial wounds. The reaction of tissues to polymeric implants was similar to their reaction to silk and was less pronounced than the reaction to catgut; it was expressed in a transient post-traumatic inflammation (up to four weeks) and the formation of a fibrous capsule less than 200 ?m thick, which became as thin as 4060 ?m after 16 weeks, in the course of reverse development. Macrophages and foreign-body giant cells with a high activity of acid phosphatase were actively involved in this process. PHB and PHB/PHV sutures implanted intramuscularly for an extended period (up to one year) did not cause any acute vascular reaction at the site of implantation or any adverse events, such as suppurative inflammation, necrosis, calcification of the fibrous capsule or malignant tumor formation. No statistically significant differences were revealed in the tissue response to polymer sutures of the two types. Capsules around silk and catgut sutures did not become significantly thinner.

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Держатели документа:
Inst. Biophys. Siberian Br. Russ. A., Akademgorodok, Krasnoyarsk 660036, Russia, Russian Federation
Terr. Pathological Anatomy Bureau, Partisan Zheleznyak St. 1, Krasnoyarsk 660049, Russia, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Shishatskaya, E.I.; Volova, T.G.; Puzyr, A.P.; Mogilnaya, O.A.; Efremov, S.N.

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