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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Vanyukov V., Mikheev G., Mogileva T., Puzyr A., Bondar V., Lyashenko D., Chuvilin A.
Заглавие : Saturable absorption in detonation nanodiamond dispersions
Место публикации : J. Nanophoton.: SPIE, 2017. - Vol. 11, Is. 3. - ISSN 19342608 (ISSN) , DOI 10.1117/1.JNP.11.032506
Ключевые слова (''Своб.индексиров.''): modelocking--nanodiamonds--nanomaterials--nonlinear optics--saturable absorption--carbon--chains--dispersion (waves)--electromagnetic wave absorption--laser excitation--laser pulses--light--light absorption--locks (fasteners)--nanostructured materials--nonlinear optics--ultrafast lasers--ultrashort pulses--yarn--aqueous dispersions--detonation nanodiamond--light-induced--modelocking--nano-diamond particles--non-linear parameters--saturable absorption--z-scan experiment--nanodiamonds
Аннотация: We report on a saturable absorption in aqueous dispersions of nanodiamonds with femtosecond laser pulse excitation at a wavelength of 795 nm. The open aperture Z-scan experiments reveal that in a wide range of nanodiamond particle sizes and concentrations, a lightinduced increase of transmittance occurs. The transmittance increase originates from the saturation of light absorption and is associated with a light absorption at 1.5 eV by graphite and dimer chains (Pandey dimer chains). The obtained key nonlinear parameters of nanodiamond dispersions are compared with those of graphene and carbon nanotubes, which are widely used for the mode-locking. © 2017 Society of Photo-Optical Instrumentation Engineers (SPIE).
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Ronzhin N. O., Posokhina E. D., Mikhlina E. V., Simunin M. M., Nemtsev I. V., Ryzhkov I. I., Bondar V. S.
Заглавие : Production of a Composite Based on Alumina Nanofibers and Detonation Nanodiamonds for Creating Phenol Indication Systems
Колич.характеристики :5 с
Коллективы : Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR) [18-29-19078 mk]
Место публикации : Dokl. Chem.: MAIK NAUKA/INTERPERIODICA/SPRINGER, 2019. - Vol. 489. - С. 267-271. - ISSN 0012-5008, DOI 10.1134/S001250081911003X. - ISSN 1608-3113(eISSN)
Примечания : Cited References:13. - This work was supported by the Russian Foundation for Basic Research (project no. 18-29-19078 mk).
Предметные рубрики: NANOPARTICLES
GRAPHENE
Аннотация: A composite of alumina nanofibers (ANF) and modified detonation nanodiamonds (MDND) was produced by mixing aqueous suspensions of the components in a weight ratio of 5 : 1 with subsequent incubation of the mixture for 15 min at 32 degrees C. It was assumed that the formation of the composite is ensured by the difference of the zeta potentials of the components, which is negative for MDND and positive for ANF. Vacuum filtration of the mixture through a fluoroplastic filter (pore diameter 0.6 mu m) formed disks 40 mm in diameter, which were then heat-treated at 300 degrees C to impart structural stability to the composite. Scanning electron microscopy detected that the obtained composite has a network structure, in which MDND particles are distributed over the surface of ANF. It was determined that the MDND particles incorporated in the composite catalyze the phenol-4-aminoantipyrine-H2O2 oxidative azo coupling reaction to form a colored product (quinoneimine). The applicability of the composite to repeated phenol detection in aqueous samples was demonstrated.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Tian M., Qiao M., Shen C., Meng F., Frank L. A., Krasitskaya V. V., Wang T., Zhang X., Song R., Li Y., Liu J., Xu S., Wang J.
Заглавие : Highly-sensitive graphene field effect transistor biosensor using PNA and DNA probes for RNA detection
Место публикации : Appl Surf Sci: Elsevier B.V., 2020. - Vol. 527. - Ст.146839. - ISSN 01694332 (ISSN), DOI 10.1016/j.apsusc.2020.146839
Аннотация: DNA probe-based biosensors have been widely developed for detecting a range of analytes. However, the DNA probe-based sensors suffer from many problems, such as long hybridization time, background electrical noise, and relatively poor specificity. In this paper, we report the ultrasensitive detection for RNA by graphene field effect transistor (G-FET) biosensor using PNA and DNA probes. The limit of detection (LOD) of the PNA probe-modified G-FET sensor is down to 0.1 aM, which is three orders of magnitude lower than that of DNA probe-modified G-FET sensor. We demonstrate that both PNA and DNA probe-modified G-FET have great potential in quantitative detection of RNA. A good linear electrical response to RNA concentrations is obtained in a broad range from 0.1 aM to 1 pM for PNA probe-modified G-FET and from 100 aM to 1 pM for DNA probe-modified G-FET, respectively. The PNA probe-modified G-FET sensors significantly reduce the detection time compared to DNA probe-modified G-FET sensors. Moreover, the electrical response of PNA probe-modified G-FET biosensor to non-complementary RNA is negligible, showing high specificity for RNA detection. What's more, the G-FET sensor was also used to detect RNA in human serum, making it a promising way for future detection of RNA in biomedical research and early clinical diagnosis. © 2020 Elsevier B.V.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Tian, Meng, Qiao, Mei, Shen, Congcong, Meng, Fanlu, Frank, Ludmila A., Krasitskaya, Vasilisa V., Wang, Tiejun, Zhang, Xiumei, Song, Ruihong, Li, Yingxian, Liu, Jianjian, Xu, Shicai, Wang, Jihua
Заглавие : Highly-sensitive graphene field effect transistor biosensor using PNA and DNA probes for RNA detection
Колич.характеристики :10 с
Коллективы : National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [11604040, 61671107]; Taishan Scholars Program of Shandong Province [tsqn201812104]; Natural Science Foundation of Shandong ProvinceNatural Science Foundation of Shandong Province [ZR2019PC026]; Qingchuang Science and Technology Plan of Shandong Province [2019KJJ017]
Место публикации : Appl. Surf. Sci.: ELSEVIER, 2020. - Vol. 527. - Ст.146839. - ISSN 0169-4332, DOI 10.1016/j.apsusc.2020.146839. - ISSN 1873-5584(eISSN)
Примечания : Cited References:62. - We are grateful for financial support from National Natural Science Foundation of China (11604040, 61671107), Taishan Scholars Program of Shandong Province (tsqn201812104), Natural Science Foundation of Shandong Province (ZR2019PC026) and Qingchuang Science and Technology Plan of Shandong Province (2019KJJ017).
Предметные рубрики: PEPTIDE NUCLEIC-ACID
LABEL-FREE DETECTION
SELECTIVE RECOGNITION
Аннотация: DNA probe-based biosensors have been widely developed for detecting a range of analytes. However, the DNA probe-based sensors suffer from many problems, such as long hybridization time, background electrical noise, and relatively poor specificity. In this paper, we report the ultrasensitive detection for RNA by graphene field effect transistor (G-FET) biosensor using PNA and DNA probes. The limit of detection (LOD) of the PNA probe modified G-FET sensor is down to 0.1 aM, which is three orders of magnitude lower than that of DNA probe modified G-FET sensor. We demonstrate that both PNA and DNA probe-modified G-FET have great potential in quantitative detection of RNA. A good linear electrical response to RNA concentrations is obtained in a broad range from 0.1 aM to 1 pM for PNA probe-modified G-FET and from 100 aM to 1 pM for DNA probe-modified GFET, respectively. The PNA probe-modified G-FET sensors significantly reduce the detection time compared to DNA probe-modified G-FET sensors. Moreover, the electrical response of PNA probe-modified G-FET biosensor to non-complementary RNA is negligible, showing high specificity for RNA detection. What's more, the G-FET sensor was also used to detect RNA in human serum, making it a promising way for future detection of RNA in biomedical research and early clinical diagnosis.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Xu S., Wang T., Liu G., Cao Z., Frank L. A., Jiang S., Zhang C., Li Z., Krasitskaya V. V., Li Q., Sha Y., Zhang X., Liu H., Wang J.
Заглавие : Analysis of interactions between proteins and small-molecule drugs by a biosensor based on a graphene field-effect transistor
Место публикации : Sens Actuators, B Chem: Elsevier B.V., 2021. - Vol. 326. - Ст.128991. - ISSN 09254005 (ISSN), DOI 10.1016/j.snb.2020.128991
Аннотация: We synthesized large-area single-crystal graphene sheets to use them in biosensors based on field-effect transistors (FET) for quantitative analysis of interaction kinetics and affinity between the imatinib drug and its target protein kinase Abl1. The G-FET biosensor showed an excellent performance and recognized imatinib at as low as 15.5 fM. The biosensor also showed a linear response to the logarithm of imatinib concentration in the 0.1 pM-10 ?M range. This graphene-based FET biosensor (G-FET) was also applied to quantify Abl1 Y253 F mutation and Abl1 dependency on Mg2+ to bind to imatinib in real-time. Results demonstrated in this work clearly showed that the novel G-FET biosensors are very promising to analyze interactions between proteins and low molecular weight drugs. © 2020 Elsevier B.V.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Xu, Shicai, Wang, Tiejun, Liu, Guofeng, Cao, Zanxia, Frank, Ludmila A., Jiang, Shouzhen, Zhang, Chao, Li, Zhenhua, Krasitskaya, Vasilisa V., Li, Qiang, Sha, Yujie, Zhang, Xiumei, Liu, Huilan, Wang, Jihua
Заглавие : Analysis of interactions between proteins and small-molecule drugs by a biosensor based on a graphene field-effect transistor
Колич.характеристики :9 с
Коллективы : Taishan Scholars Program of Shandong Province [tsqn201812104]; Qingchuang Science and Technology Plan of Shandong Province [2019KJJ017, 2020KJC004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [61671107, 62071085, 11704059, 31802309]; Youth Innovation Team Lead-Education Project of Shandong Educational Committee
Место публикации : Sens. Actuator B-Chem.: ELSEVIER SCIENCE SA, 2021. - Vol. 326. - Ст.128991. - ISSN 0925-4005(eISSN), DOI 10.1016/j.snb.2020.128991
Примечания : Cited References:66. - We are grateful for financial support from the Taishan Scholars Program of Shandong Province (tsqn201812104), the Qingchuang Science and Technology Plan of Shandong Province (2019KJJ017 and 2020KJC004), the National Natural Science Foundation of China (61671107, 62071085, 11704059, and 31802309), and the Youth Innovation Team Lead-Education Project of Shandong Educational Committee.
Предметные рубрики: LABEL-FREE DETECTION
CHEMICAL-VAPOR-DEPOSITION
DNA HYBRIDIZATION
Аннотация: We synthesized large-area single-crystal graphene sheets to use them in biosensors based on field-effect transistors (FET) for quantitative analysis of interaction kinetics and affinity between the imatinib drug and its target protein kinase Abl1. The G-FET biosensor showed an excellent performance and recognized imatinib at as low as 15.5 fM. The biosensor also showed a linear response to the logarithm of imatinib concentration in the 0.1 pM-10 mu M range. This graphene-based FET biosensor (G-FET) was also applied toquantify Abl1 Y253 F mutation and Abl1 dependency on Mg2+ to bind to imatinib in real-time. Results demonstrated in this work clearly showed that the novel G-FET biosensors are very promising to analyze interactions between proteins and low molecular weight drugs.
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