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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Dubinnyi M. A., Ivanov I. A., Rodionova N. S., Kovalchuk S. I., Kaskova Z. M., Petushkov V. N.
Заглавие : α-C-Mannosyltryptophan is a Structural Analog of the Luciferin from Bioluminescent Siberian Earthworm Henlea sp.
Место публикации : ChemistrySelect: Wiley-Blackwell, 2020. - Vol. 5, Is. 42. - С. 13155-13159. - ISSN 23656549 (ISSN), DOI 10.1002/slct.202003075
Аннотация: Cold extract from bioluminescent earthworm Henlea sp. was studied by HPLC, 1D and 2D NMR and LC-HRMS analysis. An abundant structural analog of the luciferin was isolated and identified as ?-C-mannosyltryptophan (ManTrp), the product of unusual C2-glycosylation found earlier in humans, ascidians and other animals. Two compounds in cold extract (P300b, P300c) were characterized as C2-substituted derivatives of tryptophan. We hypothesize that a series of tryptophan-containing compounds are possible participants of bioluminescence-related metabolism in Henlea sp. © 2020 Wiley-VCH GmbH
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Gribovskaya I.V., Rygalov V.Y.
Заглавие : Trace elements exchange in experimental closed life support systems
Колич.характеристики :4 с
Место публикации : SIXTH EUROPEAN SYMPOSIUM ON SPACE ENVIRONMENTAL CONTROL SYSTEMS, VOLS 1 AND 2. Ser. ESA SPECIAL PUBLICATIONS: EUROPEAN SPACE AGENCY, 1997. - Vol. 400: 6th European Symposium on Space Environmental Control Systems (MAY 20-22, 1997, NOORDWIJK, NETHERLANDS). - P859-862. - ISBN 0379-6566. - ISBN 92-9092-283-4
Примечания : Cited References: 0
Аннотация: Measurements of trace elements incoming and exiting ''Bios-3'' biological-engineering life support system evidence presence of a source of these elements inside the system. This source is, most probably, structural units (steel walls, hose rubber, plastic coatings), catalysts of the thermal catalytic incinerator, expanded clay aggregate mechanically fixing plants and so on. The trace elements are received by the nutrient solutions and build up in the plant biomass. As a consequence the crew may receive elevated doses of such trace elements as aluminum, lead, nickel, chromium. To reduce income of trace elements to LSS requires thorough selection and preliminary treatment of structural materials with reduced desorption capacities and running-in of the system in idle mode prior to exploitation. This mode involves operation of the engineering part of the system (without plants and humans, but with nutrient solutions) for several months.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Kirensky L.V., Gitelson I.I., Terskov I.A., Kovrov B.G., Lisovsky G.M., Okladnikov Y.N.
Заглавие : Theoretical and experimental decisions in the creation of an artificial ecosystem for human life support in space.
Место публикации : Life sciences and space research. - 1971. - Vol. 9. - С. 75-80. - ISSN 00759422 (ISSN)
Ключевые слова (''Своб.индексиров.''): article--bacterium--biotechnology--chlorella--energy metabolism--human--instrumentation--man machine interaction--metabolism--microclimate--space flight--weightlessness--bacteria--biotechnology--chlorella--ecological systems, closed--energy metabolism--environment, controlled--humans--life support systems--man-machine systems--space flight--weightlessness
Аннотация: All of man's former space flights were not real ventures into space in the biological sense, as his life was supported with unregenerated earth supplies. The coming stage of space exploration requires man's long existence in the cosmos and on the other planets. This stage of man's activity outside the earth become possible only by creating small man-made ecosystems, permitting the support of his metabolism by the recycling of substances of the terrestrial biosphere. Creation of such systems is a new scientific and technical task. Man-made ecosystems are a new product of man's activity, which have no complete analogy, either in nature, or in technology. Stochastic mechanisms, which stabilize biogeocenosis, cannot be effective in small ecosystems. A technique of parametric control over biosynthesis made it possible to calculate, and put to practice, an ecosystem for man with a cyclic regeneration of the atmosphere, water and, partially, food. The specific bio-technological properties of small man-made ecosystems are being analysed. The possibility of their application for man's excursions into space and for the settlement of other planets is being considered.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Tirranen L.S., Gitelson I.I.
Заглавие : The role of volatile metabolites in microbial communities of the LSS higher plant link
Место публикации : Advances in Space Research. - 2006. - Vol. 38, Is. 6. - С. 1227-1232. - ISSN 02731177 (ISSN) , DOI 10.1016/j.asr.2006.02.038
Ключевые слова (''Своб.индексиров.''): inhibiting, bactericidal, stimulating effect--microbial interaction--type of interaction--volatile and non-volatile metabolites--growth kinetics--microbiology--microorganisms--plants (botany)--sensitivity analysis--toxic materials--inhibiting, bactericidal, stimulating effect--microbial interaction--type of interaction--volatile and non-volatile metabolites--metabolites
Аннотация: The paper addresses the possibility of controlling the microbial community composition through metabolites produced by microbes. The comparative analysis of experimental data has shown that volatile metabolites make a much greater contribution to the microbial interactions than nonvolatile ones. It has been found that interaction of microorganisms via the volatiles they release occurs frequently and is typical of a number of microorganisms. Volatile metabolites released by microorganisms produce an inhibitory, sometimes bactericidal, effect on the vital functions of bacteria. The stimulating action occurs 6-8 times less frequently. The range of action on the growth of the test cultures and the range of sensitivity to the effect of volatile metabolites of the study microbes have been found to be individual. Comparative cluster analysis of the ranges of action of 100 study cultures has shown that in the investigated set of microorganism species interaction was performed via a set of volatiles of an inhibiting action (82) and of a stimulating action (52). It has been found that release of volatile metabolites by the studied microorganisms depends upon the culture age, concentrations of components of the nutrient medium, and volatile by-products released by other microorganisms. This production can be increased or decreased by the action of volatile metabolites of other microbes. This is related to strain features and culture age. The prospects of using these regulating metabolites depend on the "range", specificity and safety for other members of the microbial community in insufficient concentrations. Volatiles produced by plants and microorganisms as well as by other components of the system - humans and processing equipment installed inside the closed ecosystem - could influence the formation not only of the microbial community but also of the gas composition of the system's atmosphere, through which they could affect the state of the plants. Specially performed experiments have shown that volatile metabolites of microorganisms can accumulate in their habitat, dissolve in the atmospheric water, and maintain their biological activity for days. It has been determined that volatile metabolites of some microorganisms are toxic for plants. Growth of seedling roots is inhibited more than growth of stems. В© 2006 COSPAR.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Pechurkin N.S., Shuvaev A.N.
Заглавие : The general evolution of energy–matter interactions on earth: From a gas whirlwind to a technogenic civilization
Место публикации : Biophysics. - 2015. - Vol. 60, Is. 2. - С. 331-334. - ISSN 00063509 (ISSN) , DOI 10.1134/S0006350915020153
Ключевые слова (''Своб.индексиров.''): biosphere--energy transfer--evolution--animalia--mammalia--protozoa
Аннотация: An idea of the general evolution through the long-term response of the Earth to the external flow of radiant energy from the Sun is proposed. Due to the finiteness of matter on Earth, as well as on any other planet, the continuous pumping flow of radiant energy has been shown to lead to cyclization of transformations and mass transfer along the emerging gradients. The evolution of the energy–matter interaction follows the pathway of capturing and transferring more energy by a smaller quantity of matter, i.e., the pathway of the increase in the amount of energy used by each unit mass. According to this parameter, the least effective mass transfer is a simple transfer as vortices of gases along the gradients of temperature and pressure, which took place on the primary surface of the planet. Long-term natural selection towards water accumulation on the planet has played a special role in the development of the interaction between energy and matter. Phase transitions (ice, water, and vapor) and mechanical transfers are the most common energy–matter processes. Chemical transformation of substances became possible based on water cycles, cyclic transfers, and transformations and developed with time into biological transformation. This type of energy–matter interaction is the most efficient. In particular, the energy of our star is captured during photosynthesis and utilized in the most active region of its radiation spectrum. During the biological evolution of heterotrophs, a increase in the coefficient that characterizes the energy exchange intensity from protozoa to mammals by several hundred times is most illustrative. The development and current dominance of humans as the species that is most active in the capturing of energy and meaningful organization of its new flows, in particular, based on the organic debris of former biospheres, is amazing but quite natural from the energy standpoint. During the technological evolution of humankind, the energy-exchange intensity for homoiotherms (warm-blooded animals) has increased by 20 times if it is recalculated for the technological energy that is used by the average inhabitant of the Earth. Thus, the victory of our species in planetary evolution fits well into the mainstream of the general evolution through energy–matter interactions: a multiple increase in star energy has been used to transform the matter on the surface of the irradiated planet. © 2015, Pleiades Publishing, Inc.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Ovchinnikova T.M., Savchenko A.A., Sukhovol'skii V.G., Khlebopros R.G.
Заглавие : Structural and temporal links between the components of humoral immunity.
Место публикации : Doklady Biochemistry. - 2000. - Vol. 374, Is. 1-6. - С. 186-188. - ISSN 00124958 (ISSN)
Ключевые слова (''Своб.индексиров.''): immunoglobulin a--immunoglobulin d--immunoglobulin g--immunoglobulin m--antibody production--article--biological model--blood--herpes simplex--human--immunology--physiology--regression analysis--antibody formation--herpes simplex--humans--immunoglobulin a--immunoglobulin d--immunoglobulin g--immunoglobulin m--models, immunological--regression analysis
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Ushakova S.A., Zolotukhin I.G., Tikhomirov A.A., Tikhomirova N.A., Kudenko Yu.A., Gribovskaya I.V., Balnokin Yu., Gros J.B.
Заглавие : Some methods for human liquid and solid waste utilization in bioregenerative life-support systems
Место публикации : Applied Biochemistry and Biotechnology. - 2008. - Vol. 151, Is. 2-3. - С. 676-685. - ISSN 02732289 (ISSN) , DOI 10.1007/s12010-008-8291-3
Ключевые слова (''Своб.индексиров.''): closure--human waste--life-support systems--salicornia--sodium chloride--above-ground biomass--biological lives--bioregenerative--closure--cultivation process--culture methods--human waste--irrigation waters--life-support systems--manned space missions--mineral elements--physico-chemical methods--salicornia--salicornia europaea--salt-tolerant--soil-like substrates--biomass--body fluids--electrodialysis--grain (agricultural product)--irrigation--liquids--metal refining--minerals--mining--oxidation--plant shutdowns--sodium chloride--soils--solid wastes--substrates--water supply--vegetation--article--biomass--controlled study--electrodialysis--halophyte--irrigation (agriculture)--microclimate--nonhuman--recycling--salicornia europaea--solid waste--bioremediation--dialysis--feces--goosefoot--growth, development and aging--human--methodology--salt tolerance--urine--waste management--wheat--batis maritima--salicornia--salicornia europaea--triticum aestivum--biodegradation, environmental--chenopodiaceae--dialysis--feces--humans--life support systems--salt-tolerance--triticum--urine--waste management
Аннотация: Bioregenerative life-support systems (BLSS) are studied for developing the technology for a future biological life-support system for long-term manned space missions. Ways to utilize human liquid and solid wastes to increase the closure degree of BLSS were investigated. First, urine and faeces underwent oxidation by Kudenko's physicochemical method. The products were then used for root nutrition of wheat grown by the soil-like substrate culture method. Two means of eliminating sodium chloride, introduced into the irrigation solution together with the products of urine oxidation, were investigated. The first was based on routine electrodialysis of irrigation water at the end of wheat vegetation. Dialysis eliminated about 50% of Na from the solution. This desalinization was performed for nine vegetations. The second method was new: after wheat cultivation, the irrigation solution and the solution obtained by washing the substrate containing mineral elements not absorbed by the plants were used to grow salt-tolerant Salicornia europaea L. plants (saltwort). The above-ground biomass of this plant can be used as a food, and roots can be added to the soil-like substrate. Four consecutive wheat and Salicornia vegetations were cultivated. As a result of this wheat and Salicornia cultivation process, the soil-like substrate salinization by NaCl were considerably decreased. В© 2008 Humana Press.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Gladyshev M. I., Sushchik N. N., Shulepina S. P., Ageev A. V., Dubovskaya O. P., Kolmakova A. A., Kalachova G. S.
Заглавие : Secondary Production of Highly Unsaturated Fatty Acids by Zoobenthos Across Rivers Contrasting in Temperature
Колич.характеристики :12 с
Коллективы : Siberian Federal University [6.1089.214/K]; Russian Federal Tasks of Fundamental Research [51.1.1]
Место публикации : River Res. Appl.: WILEY-BLACKWELL, 2016. - Vol. 32, Is. 6. - С. 1252-1263. - ISSN 1535-1459, DOI 10.1002/rra.2945. - ISSN 1535-1467(eISSN)
Примечания : Cited References:55. - The work was supported by the project no. 6.1089.214/K of Siberian Federal University carried out according to Federal Tasks of Ministry of Education and Science of Russian Federation and by Russian Federal Tasks of Fundamental Research (project no. 51.1.1).
Предметные рубрики: AQUATIC ECOSYSTEMS
CLIMATE-CHANGE
YENISEI RIVER
ALPINE PONDS
LAKE
Ключевые слова (''Своб.индексиров.''): essential polyunsaturated fatty acids--river zoobenthos--secondary--production--biodiversity--water temperature--climate warming
Аннотация: Highly unsaturated fatty acids (HUFA), namely eicosapentaenoic acid (20:5n-3, EPA) and docosahexaenoic acid (22:6n-3, DHA), which are essential for many animals, including humans, are mainly produced in aquatic trophic webs. In fast-flowing rivers, macrozoobenthos is the main source of HUFA for fish and may be particularly vulnerable to thermal alterations associated with climate change. We studied benthic communities in a unique natural ecosystem: the Yenisei River downstream of the dam of Krasnoyarsk Hydroelectric Power Station with very low temperature in summer because of discharge of cold water from deep in the reservoir and its tributaries with high summer temperature. This natural experiment' allowed to get rid of confounding factors, such as differences in light, seasonality, geology (biogeochemistry) and biogeography (regional species pools). As found, in spite of an increase of biodiversity and rates of daily production in warm rivers compared with cold sites, DHA and partly EPA production of zoobenthos decreased with the increase of temperature because of changes in species composition. Thus, in a climate warming context, we can predict a decrease of production of these HUFA by river zoobenthos and thereby a diminishing of their supply for fish and next to humans. Copyright (c) 2015 John Wiley & Sons, Ltd.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Sushchik N.N.
Заглавие : Role of essential fatty acids in trophometabolic interactions in the freshwater ecosystems (a review)
Место публикации : Zhurnal Obshchei Biologii. - 2008. - Vol. 69, Is. 4. - С. 299-316. - ISSN 00444596 (ISSN)
Ключевые слова (''Своб.индексиров.''): essential fatty acid--fresh water--animal--article--ecosystem--fish--food chain--human--metabolism--phytoplankton--zooplankton--animals--ecosystem--fatty acids, essential--fishes--food chain--fresh water--humans--phytoplankton--zooplankton--algae--animalia--bacteria (microorganisms)--invertebrata--vertebrata
Аннотация: Polyunsaturated fatty acids (PUFA) of ?3 family are of crucial physiological importance for the most animals and they are an essential and deficient component of human nutrition. These compounds are most effectively synthesized by some groups of algae, hence, aquatic ecosystems are considered to be the main source of these PUFA for human nutrition. Factors controlling the content and distribution of ?3 PUFA in freshwater organisms of basic trophic levels and determined PUFA final production in freshwater ecosystems are considered in the review. PUFA biosynthesis is known to be tightly related to basic fatty acid metabolic pathways. Hence, fatty composition and the PUFA content of major freshwater hydrobiont groups, including bacteria, algae, invertebrates and vertebrates, and environmental and population age effects are described. The peculiarities of PUFA transfer between organisms of various trophic levels are discussed. The essential ?3 PUFA is one of the important parameter of food quality of aquatic consumers and they can determine the rate of energy and matter transfer between producers and primary consumers and, as a result, in a whole freshwater food chain. Analysis of PUFA content and its regulation in biomass of various fish populations indicates that freshwater ecosystems are of the same value in respect of PUFA sources as marine ecosystems. Despite the great practical importance, the studies focused on production and whole pools of ?3 PUFA in different freshwater ecosystems are still scarce and need to be continued.
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10.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Bondar V.S., Ronzhin N.O., Mamaeva E.S., Baron A.V., Gitelson J.I.
Заглавие : Reusable biochemical diagnosis systems based on nanodiamonds
Место публикации : Doklady Biochemistry and Biophysics. - 2013. - Vol. 448, Is. 1. - С. 55-58. - ISSN 16076729 (ISSN) , DOI 10.1134/S160767291301016X
Ключевые слова (''Своб.индексиров.''): cholesterol--diamond--nanoparticle--article--bioassay--blood--chemical model--chemistry--glucose blood level--human--methodology--biological assay--blood glucose--cholesterol--diamond--humans--models, chemical--nanoparticles
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11.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Gladyshev M. I.
Заглавие : Quality and Quantity of Biological Production in Water Bodies with Different Concentration of Phosphorus: Case Study of Eurasian Perch
Колич.характеристики :3 с
Коллективы : Russian Academy of Sciences [II.2P/VI.51-1]; State task of the Ministry of Education and Science of the Russian Federation [6.1504.2017/PCh]; Council for Grants of the President of the Russian Federation for State Support of Leading Scientific Schools [NSh-9249.2016.5]
Место публикации : Dokl. Biochem. Biophys.: MAIK NAUKA/INTERPERIODICA/SPRINGER, 2018. - Vol. 478, Is. 1. - С. 1-3. - ISSN 1607-6729, DOI 10.1134/S1607672918010015. - ISSN 1608-3091(eISSN)
Примечания : Cited References:15. - This work was supported by the project of the Russian Academy of Sciences no. II.2P/VI.51-1, the State task of the Ministry of Education and Science of the Russian Federation to the Siberian Federal University for research no. 6.1504.2017/PCh, and the Council for Grants of the President of the Russian Federation for State Support of Leading Scientific Schools (project no. NSh-9249.2016.5).
Предметные рубрики: POLYUNSATURATED FATTY-ACIDS
EPA
DHA
Аннотация: For the first time, the quantity of protectors of cardiovascular deceases-omega-3 polyunsaturated fatty acids, eicosapentaenoic (20:5n-3, EPA) and docosahexaenoic (22:6n-3, DHA), obtained through fish (Eurasian perch) catch in water bodies of different trophic status was determined. A formula was drawn to calculate the quantity of obtained EPA + DHA (kg km(-2) year(-1)) depending on the concentration of total phosphorus in water. It is found that the maximum quantity of EPA + DHA can be obtained by humans from fish caught in mesotrophic water bodies.
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12.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Sevastianov V.I., Perova N.V., Shishatskaya E.I., Kalacheva G.S., Volova T.G.
Заглавие : Production of purified polyhydroxyalkanoates (PHAs) for applications in contact with blood
Место публикации : Journal of Biomaterials Science, Polymer Edition. - 2003. - Vol. 14, Is. 10. - С. 1029-1042. - ISSN 09205063 (ISSN) , DOI 10.1163/156856203769231547
Ключевые слова (''Своб.индексиров.''): ?-hydroxy acids--endotoxins--hemocompatibility--poly(hydroxybutyrate-co-hydroxyvalerate) (phbv)--polyhydroxyalkanoates (phas)--polyhydroxybutyrate (phb)--bacterium lipopolysaccharide--carbon--complement--copolymer--hydroxyacid--long chain fatty acid--poly(3 hydroxybutyric acid)--polyhydroxyalkanoic acid--valeric acid derivative--adult--article--biofilm--biotechnology--blood analysis--blood clotting--blood compatibility--cell function--chemical analysis--chemical composition--complement activation--concentration (parameters)--controlled study--gas chromatography--hemostasis--human--human cell--mass spectrometry--micromorphology--nonhuman--priority journal--purification--quantitative analysis--sampling--synthesis--thrombocyte adhesion--wautersia eutropha--biocompatible materials--blood--blood coagulation tests--chromatography, gas--complement activation--cupriavidus necator--fatty acids--humans--platelet adhesiveness--polyesters--surface properties
Аннотация: Samples of olyhydroxyalkanoates (PHAs), polyhydroxybutyrate (PHB) and copolymers poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) with 4 and 18 mol% hydroxyvalerate, synthesized by the bacteria Ralstonia eutropha B5786, were investigated. PHA films in contact with blood did not activate the hemostasis system at the level of cell response, but they did activate the coagulation system and the complement reaction. To detect biologically-active components in the PHAs, a detailed analysis of the composition of the polymers was conducted. Gas chromatography-mass spectrometry revealed long-chain fatty acids (FAs) in the tested PHAs. Their total concentration in the polymer ranged from tenths of mol% to 2-3 mol%, depending on the purification method. C16:0 constituted the largest proportion, up to 70%. Of the long-chain hydroxy acids, only ?-OH-C14:0 was detected and it did not exceed 0.06 mol%. The analysis of the hemocompatibility properties of the PHAs purified by a specialized procedure, including the quantitative and morphological estimation of platelets adherent to the surface of polymer films, the plasma recalcification time and complement activation studies, indicated that PHB and PHBV can be used in contact with blood. It has been found out that the lipopolysaccharides of bacteria producing PHAs, which contain mostly long-chain hydroxy acids, can be the factor activating the hemostasis systems. Thus, the technology of PHA purification must satisfy rather stringent specific requirements.
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13.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Gladyshev M.I., Sushchik N.N., Makhutova O.N.
Заглавие : Production of EPA and DHA in aquatic ecosystems and their transfer to the land
Место публикации : Prostaglandins and Other Lipid Mediators. - 2013. - ISSN 10988823 (ISSN) , DOI 10.1016/j.prostaglandins.2013.03.002
Ключевые слова (''Своб.индексиров.''): aquatic ecosystems--docosahexaenoic acid--eicosapentaenoic acid--trophic transfer efficiency
Аннотация: Most omnivorous animals, including humans, have to some degree relied on physiologically important polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from food. Only some taxa of microalgae, rather than higher plants can synthesize de novo high amounts of EPA and DHA. Once synthesized by microalgae, PUFA are transferred through trophic chain to organisms of higher levels. Thus, aquatic ecosystems play the unique role in the Biosphere as the principal source of EPA and DHA for most omnivorous animals, including inhabitants of terrestrial ecosystems. PUFA are transferred from aquatic to terrestrial ecosystems through riparian predators, drift of carrion and seaweeds, emergence of amphibiotic insects, and water birds. The essential PUFA are transferred through trophic chains with about twice higher efficiency than bulk carbon. Thereby, PUFA are accumulated, rather than diluted in biomass of organisms of higher trophic levels, e.g., in fish. Mankind is faced with a severe deficiency of EPA and DHA in diet. Although additional sources of PUFA supply for humans, such as aquaculture, biotechnology of microorganisms and transgenic terrestrial oil-seed producing plants are developed, natural fish production of aquatic ecosystems will remain one of the main sources of EPA and DHA for humans. Aquatic ecosystems have to be protected from anthropogenic impacts, such as eutrophication, pollution and warming, which reduce PUFA production. В© 2013 Elsevier Inc. All rights reserved.
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14.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Gladyshev M.I., Sushchik N.N., Makhutova O.N.
Заглавие : Production of EPA and DHA in aquatic ecosystems and their transfer to the land
Коллективы : Russian Foundation for Basic Research (RFBR) [11-04-00168, 12-05-00298]; project B-15 of Siberian Federal University
Место публикации : Prostaglandins Other Lipid Mediat.: ELSEVIER SCIENCE INC, 2013. - Vol. 107. - С. 117-126. - 10. - ISSN 1098-8823, DOI 10.1016/j.prostaglandins.2013.03.002
Примечания : Cited References: 129. - This work was supported by grants of Russian Foundation for Basic Research (RFBR) No. 11-04-00168 and No. 12-05-00298, and also by the project B-15 of Siberian Federal University, carried out according to Federal Tasks of Ministry of Education and Science of Russian Federation. We are grateful to two anonymous reviewers for their helpful comments to improve the manuscript.
Предметные рубрики: POLYUNSATURATED FATTY-ACIDS
FRESH-WATER FISH
EICOSAPENTAENOIC ACID
DOCOSAHEXAENOIC ACID
YENISEI RIVER
BIOTECHNOLOGICAL PRODUCTION
ARBUSCULAR MYCORRHIZAL
CAENORHABDITIS-ELEGANS
MICROBIAL COMMUNITY
THYMALLUS-ARCTICUS
Ключевые слова (''Своб.индексиров.''): eicosapentaenoic acid--docosahexaenoic acid--aquatic ecosystems--trophic transfer efficiency
Аннотация: Most omnivorous animals, including humans, have to some degree relied on physiologically important polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from food. Only some taxa of microalgae, rather than higher plants can synthesize de novo high amounts of EPA and DHA. Once synthesized by microalgae, PUFA are transferred through trophic chain to organisms of higher levels. Thus, aquatic ecosystems play the unique role in the Biosphere as the principal source of EPA and DHA for most omnivorous animals, including inhabitants of terrestrial ecosystems. PUFA are transferred from aquatic to terrestrial ecosystems through riparian predators, drift of carrion and seaweeds, emergence of amphibiotic insects, and water birds. The essential PUFA are transferred through trophic chains with about twice higher efficiency than bulk carbon. Thereby, PUFA are accumulated, rather than diluted in biomass of organisms of higher trophic levels, e.g., in fish. Mankind is faced with a severe deficiency of EPA and DHA in diet. Although additional sources of PUFA supply for humans, such as aquaculture, biotechnology of microorganisms and transgenic terrestrial oil-seed producing plants are developed, natural fish production of aquatic ecosystems will remain one of the main sources of EPA and DHA for humans. Aquatic ecosystems have to be protected from anthropogenic impacts, such as eutrophication, pollution and warming, which reduce PUFA production. (C) 2013 Elsevier Inc. All rights reserved.
WOS,
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15.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Slepkov V.A., Sukhovol'skiy V.G., Khlebopros R.G.
Заглавие : Population model for malignant tumor and organism interaction
Место публикации : Doklady Biological Sciences. - 2010. - Vol. 430, Is. 1. - С. 17-19. - ISSN 00124966 (ISSN) , DOI 10.1134/S0012496610010060
Ключевые слова (''Своб.индексиров.''): article--biological model--cancer invasion--human--neoplasm--pathophysiology--humans--models, biological--neoplasm invasiveness--neoplasms
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16.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Kalyabina, Valeriya P., Esimbekova, Elena N., Kopylova, Kseniya, V, Kratasyuk, Valentina A.
Заглавие : Pesticides: formulants, distribution pathways and effects on human health-a review
Колич.характеристики :14 с
Коллективы : Government of Krasnoyarsk Territory, Krasnoyarsk Regional Fund of Science; Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR) [20-44-242001]
Место публикации : Toxicol. Rep.: ELSEVIER, 2021. - Vol. 8. - С. 1179-1192. - ISSN 2214-7500(eISSN), DOI 10.1016/j.toxrep.2021.06.004
Примечания : Cited References:211. - The research was funding by the Government of Krasnoyarsk Territory, Krasnoyarsk Regional Fund of Science and Russian Foundation for Basic Research (project No 20-44-242001).
Предметные рубрики: GLYPHOSATE-BASED HERBICIDES
ENDOCRINE-DISRUPTING CHEMICALS
IN-VITRO
Аннотация: Pesticides are commonly used in agriculture to enhance crop production and control pests. Therefore, pesticide residues can persist in the environment and agricultural crops. Although modern formulations are relatively safe to non-target species, numerous theoretical and experimental data demonstrate that pesticide residues can produce long-term negative effects on the health of humans and animals and stability of ecosystems. Of particular interest are molecular mechanisms that mediate the start of a cascade of adverse effects. This is a review of the latest literature data on the effects and consequences of contamination of agricultural crops by pesticide residues. In addition, we address the issue of implicit risks associated with pesticide formulations. The effects of pesticides are considered in the context of the Adverse Outcome Pathway concept.
WOS
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17.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Kalyabina V. P., Esimbekova E. N., Kopylova K. V., Kratasyuk V. A.
Заглавие : Pesticides: formulants, distribution pathways and effects on human health – a review
Место публикации : Toxicol. Rep.: Elsevier Inc., 2021. - Vol. 8. - С. 1179-1192. - ISSN 22147500 (ISSN), DOI 10.1016/j.toxrep.2021.06.004
Аннотация: Pesticides are commonly used in agriculture to enhance crop production and control pests. Therefore, pesticide residues can persist in the environment and agricultural crops. Although modern formulations are relatively safe to non-target species, numerous theoretical and experimental data demonstrate that pesticide residues can produce long-term negative effects on the health of humans and animals and stability of ecosystems. Of particular interest are molecular mechanisms that mediate the start of a cascade of adverse effects. This is a review of the latest literature data on the effects and consequences of contamination of agricultural crops by pesticide residues. In addition, we address the issue of implicit risks associated with pesticide formulations. The effects of pesticides are considered in the context of the Adverse Outcome Pathway concept. © 2021 The Author(s)
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18.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Bartsev S.I., Gitelson J.I., Lisovsky G.M., Mezhevikin V.V., Okhonin V.A.
Заглавие : Perspectives of different type biological life support systems (BLSS) usage in space missions
Место публикации : Acta Astronautica. - 1996. - Vol. 39, Is. 8. - С. 617-622. - ISSN 00945765 (ISSN) , DOI 10.1016/S0094-5765(97)00012-X
Ключевые слова (''Своб.индексиров.''): article--bacterium--comparative study--construction work and architectural phenomena--environmental planning--green alga--human--instrumentation--mathematics--microclimate--moon--plant--quality of life--space flight--standard--weightlessness--algae, green--bacteria--ecological systems, closed--environment design--environment, controlled--facility design and construction--humans--life support systems--mathematics--moon--plants--quality of life--space flight--weightlessness--biology--life support systems (spacecraft)--spreadsheets--biological life support systems (blss)--lunar missions
Аннотация: In the paper an attempt is made to combine three important criteria of LSS comparison: minimum mass, maximum safety and maximum quality of life. Well-known types of BLSS were considered: with higher plant, higher plants and mushrooms, microalgae, and hydrogen-oxidizing bacteria. These BLSSs were compared in terms of "integrated" mass for the case of a vegetarian diet and a "normal" one (with animal proteins and fats). It was shown that the BLSS with higher plants and incineration of wastes becomes the best when the exploitation period is more than 1 yr. The dependence of higher plants' LSS structure on operation time was found. Comparison of BLSSs in terms of integral reliability (this criterion includes mass and quality of life criteria) for a lunar base scenario showed that BLSSs with higher plants are advantageous in reliability and comfort. This comparison was made for achieved level of technology of closing and for perspective one. В© 1997 Elsevier Science Ltd.
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19.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Lobova T.I., Barkhatov Y.V., Salamatina O.V., Popova L.Yu.
Заглавие : Multiple antibiotic resistance of heterotrophic bacteria in the littoral zone of Lake Shira as an indicator of human impact on the ecosystem
Место публикации : Microbiological Research. - 2008. - Vol. 163, Is. 2. - С. 152-160. - ISSN 09445013 (ISSN) , DOI 10.1016/j.micres.2006.03.014
Ключевые слова (''Своб.индексиров.''): antibiotic resistance--aquatic ecosystems--heterotrophic bacteria--human impact--monitoring--antibiotics--bacteria--ecosystems--environmental impact--mammals--antibiotic resistance--aquatic ecosystems--heterotrophic bacteria--materials--antiinfective agent--fresh water--allochthony--anthropogenic effect--antibiotic resistance--bacterium--concentration (composition)--heterotrophy--intertidal environment--monitoring--recreational facility--spring (season)--summer--animal--article--bacterial count--bacterium--drug effect--ecosystem--environmental monitoring--heterotrophy--human--isolation and purification--methodology--microbiological examination--microbiology--multidrug resistance--russian federation--season--animals--anti-bacterial agents--bacteria--colony count, microbial--drug resistance, multiple, bacterial--ecosystem--environmental monitoring--fresh water--heterotrophic processes--humans--microbial sensitivity tests--russia--seasons--eurasia--khakassia--lake shira--russian federation--animalia--bacteria (microorganisms)
Аннотация: Resistance to Ampicillin and Kanamycin displayed by heterotrophic bacteria isolated in Summer and in Spring from the littoral and the central parts of Lake Shira (a therapeutic lake in the Khakasia Republic, Russia) has been investigated. It has been found that in Summer, human and animal microflora featuring multiple antibiotic resistance (to Ampicillin and Kanamycin) predominates in all the studied stations of the littoral zone of the lake. In Spring, concentrations of bacteria featuring multiple antibiotic resistance decrease significantly and bacteria sensitive to antibiotics predominate in the lake. Emergence of multiple antibiotic resistance in bacteria of Lake Shira is caused by the input of allochthonous bacteria into the lake; this feature of heterotrophic bacteria of Lake Shira can be used to monitor the impact on the ecosystem made by health resorts. В© 2006 Elsevier GmbH. All rights reserved.
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20.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Slepkov V.A., Sukhovol'skii V.G., Khlebopros R.G.
Заглавие : Modeling the growth and morphogenesis of malignant tumors
Место публикации : Doklady Biochemistry and Biophysics. - 2006. - Vol. 411, Is. 1. - С. 342-345. - ISSN 16076729 (ISSN) , DOI 10.1134/S1607672906060056
Ключевые слова (''Своб.индексиров.''): animal--article--biological model--cancer invasion--cell proliferation--computer simulation--human--morphogenesis--neoplasm--pathology--pathophysiology--animals--cell proliferation--computer simulation--humans--models, biological--morphogenesis--neoplasm invasiveness--neoplasms
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