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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Ronzhin, Nikita O., Posokhina, Ekaterina D., Mikhlina, Elena, V, Mikhlin, Yuri L., Simunin, Mikhail M., Tarasova, Lyudmila S., Vorobyev, Sergey A., Bondar, Vladimir S., Ryzhkov, Ilya I.
Заглавие : A new composite material based on alumina nanofibers and detonation nanodiamonds: synthesis, characterization, and sensing application
Колич.характеристики :14 с
Коллективы : Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR) [18-29-19078]
Место публикации : J. Nanopart. Res.: SPRINGER, 2021. - Vol. 23, Is. 9. - Ст.199. - ISSN 1388-0764, DOI 10.1007/s11051-021-05309-y. - ISSN 1572-896X(eISSN)
Примечания : Cited References:57. - This work is partially supported by the Russian Foundation for Basic Research, Project 18-29-19078 (E. V. Mikhlina, M. M. Simunin, I. Ryzhkov).
Предметные рубрики: ELECTROCHEMICAL ENERGY-STORAGE
SELECTIVE DETECTION
PHENOL DETECTION
Аннотация: The development of inexpensive, easy-to-produce, and easy-to-use analytical tools for detection of harmful and toxic substances is a relevant research problem with direct applications in environmental monitoring and protection. In this work, we propose a novel composite material based on alumina nanofibers and detonation nanodiamonds for detection of phenol in aqueous medium. The composite material was obtained by mixing an aqueous suspension of alumina nanofibers with a diameter of 10-15 nm and a length of several microns and a hydrosol of nanodiamonds with an average cluster size of 70 nm. The mechanisms underlying the interaction of these nanomaterials are clarified and the physicochemical properties of the composite are investigated. The SEM and TEM studies show that the obtained composite has a network structure, in which clusters of nanodiamonds (10-20 nm in diameter) are distributed over the surface of nanofibers. Coupling of nanomaterials occurs due to opposite signs of their zeta potentials, which results in electrostatic attraction and subsequent chemical bonding as indicated by the X-ray photoelectron spectroscopy and simultaneous thermal analysis. The bonding apparently occurs between functional groups (mainly carboxyl) on the surface of nanodiamonds and amphoteric hydroxyl groups on the surface of alumina nanofibers. The proposed composite allows an easy-to-perform colorimetric analysis for qualitative and quantitative determination of phenol in aqueous samples with linear response over a wide range of concentrations (0.5-106 mu M). Multiple tests have shown that the composite is reusable and retains its catalytic function for at least 1 year during storage at room temperature.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Anand A., Saran M., Chaudhary S., Ronin R. S., Swami A. K., Mathur M., Burov A., Bagaria A.
Заглавие : A Novel Approach Towards Green Synthesis of Nanodiamonds as Biocompatible Agents
Место публикации : J. Nano. Electron. Phys.: Sumy State University, 2021. - Vol. 13, Is. 3. - С. 1-6. - ISSN 20776772 (ISSN), DOI 10.21272/jnep.13(3).03040
Аннотация: The application of nanobiotechnology is an emerging area of nanoscience and nanotechnology. Nanodi-amond has been a potent antibacterial, antifungal, antioxidant, and antiplatelet agent. In the present study, nanodiamonds were reduced by green synthesis and characterization was done through SEM, TEM, FTIR, and XRD. Further they were tested for their biological applications. The antimicrobial activity was investigated/studied/examined? through well diffusion method. The best activity was observed against Trichoderma reesei (16 mm) at 140 ?g/ml. The antioxidant activity was investigated through DPPH and FRAPS method. It was observed that the biologically reduced nanodiamonds reduce the Fe3+ ions to Fe2+ ions at 600 mM/l/g concentration. In DPPH assay, inhibitory concentration was found to be 4.58 ?g/ml. Further the antiplatelet activity was investigated by prothrombin time (PT) and activated partial throm-boplastin time (APTT) assay, and it was observed that biologically reduced nanodiamonds have potent an-tiplatelet activity. © 2021 Sumy State University
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Baron A. V., Osipov N. V., Yashchenko S. V., Kokotukha Y. A., Baron I. J., Puzyr A. P., Olkhovskiy I. A., Bondar V. S.
Заглавие : Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds
Место публикации : Doklad. Biochem. Biophys.: Maik Nauka Publishing / Springer SBM, 2016. - Vol. 469, Is. 1. - С. 244-246. - ISSN 16076729 (ISSN) , DOI 10.1134/S1607672916040037
Аннотация: Adsorption of viral particles from the blood plasma of patients with viral hepatitis B and C on modified nanodiamonds (MNDs) was shown in the in vitro experiments. PCR method showed the treatment of plasma with MNDs leads to a decrease in the viral load by 2–3 orders of magnitude or more in both cases studied. These results make it possible to predict the applicability of MNDs for the development of new technologies of hemodialysis and plasmapheresis for binding and removal of viral particles from the blood of infected patients. © 2016, Pleiades Publishing, Ltd.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Bondar' V.S., Pozdnyakova I.O., Puzyr' A.P.
Заглавие : Applications of nanodiamonds for separation and purification of proteins
Колич.характеристики :3 с
Место публикации : Phys. Solid State: AMER INST PHYSICS, 2004. - Vol. 46, Is. 4. - С. 758-760. - ISSN 1063-7834, DOI 10.1134/1.1711468
Примечания : Cited References: 11
Предметные рубрики: ESCHERICHIA-COLI
OBELIN
Аннотация: Recombinant apoobelin and recombinant luciferase are separated from bacterial cells of Escherichia coli with the use of detonation nanodiamonds. The application of nanodiamonds has a number of points in its favor, namely, (i) simplifies the procedures for purifying the proteins, (ii) decreases the time of their separation to 30-40 min, (iii) eliminates the necessity of using special chromatographic equipment, and (iv) makes it possible to prepare high-purity apoobelin and luciferase materials with protein yields of 35-45 and 45-60%, respectively. The possible mechanisms of interaction of protein molecules and nanodiamond particles are analyzed. (C) 2004 MAIK "Nauka / Interperiodica".
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Baron A.V., Osipov N.V., Olkhovskiy I.A., Puzyr A.P., Bondar V.S.
Заглавие : Binding the immunoglobulins of human serum by nanodiamonds
Колич.характеристики :2 с
Коллективы : Presidium of the Russian Academy of Sciences [24, 57]
Место публикации : Dokl. Biochem. Biophys.: MAIK NAUKA/INTERPERIODICA/SPRINGER, 2014. - Vol. 457, Is. 1. - С. 158-159. - ISSN 1607-6729, DOI 10.1134/S1607672914040127. - ISSN 1608-3091
Примечания : Cited References: 8. - This study was supported by the Presidium of the Russian Academy of Sciences (program no. 24, project no. 57).
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Inzhevatkin E. V., Baron A. V., Volkova M. B., Maksimov N. G., Golubenko N. K., Loshkareva M. V., Puzyr’ A. P., Ronzhin N. O., Bondar V. S.
Заглавие : Biodistribution of Detonation Synthesis Nanodiamonds in Mice after Intravenous Administration and Some Biochemical Changes in Blood Plasma
Место публикации : Bull. Exp. Biol. Med.: Springer, 2021. - Article in press. - ISSN 00074888 (ISSN), DOI 10.1007/s10517-021-05335-9
Аннотация: Biodistribution of nanodiamonds in mice after intravenous administration, activities of AST and ALT, and the level of bilirubin in the blood plasma were studied in 2.5 h and 10, 35, and 97 days after injection of nanodiamonds. In 2.5 h after intravenous injection, nanodiamonds mainly accumulate in the lungs and liver. Then, redistribution of nanodiamonds from all organs to the liver was observed. Activities of AST and ALT and the level of bilirubin in the blood increased after 2.5 h and then decreased to the initial values. © 2021, Springer Science+Business Media, LLC, part of Springer Nature.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Inzhevatkin, E., V, Baron, A., V, Volkova M. B., Maksimov N. G., Golubenko N. K., Loshkareva, M., V, Puzyr' A. P., Ronzhin N. O., Bondar V. S.
Заглавие : Biodistribution of Detonation Synthesis Nanodiamonds in Mice after Intravenous Administration and Some Biochemical Changes in Blood Plasma
Колич.характеристики :4 с
Место публикации : Bull. Exp. Biol. Med.: SPRINGER, 2021. - Vol. 172, Is. 1. - С. 77-80. - ISSN 0007-4888, DOI 10.1007/s10517-021-05335-9. - ISSN 1573-8221(eISSN)
Примечания : Cited References:9
Аннотация: Biodistribution of nanodiamonds in mice after intravenous administration, activities of AST and ALT, and the level of bilirubin in the blood plasma were studied in 2.5 h and 10, 35, and 97 days after injection of nanodiamonds. In 2.5 h after intravenous injection, nanodiamonds mainly accumulate in the lungs and liver. Then, redistribution of nanodiamonds from all organs to the liver was observed. Activities of AST and ALT and the level of bilirubin in the blood increased after 2.5 h and then decreased to the initial values.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Inzhevatkin, Evgeny, Baron, Alexey, Maksimov, Nikolai, Volkova, Marina, Puzyr, Alexey, Ronzhin, Nikita, Bondar, Vladimir
Заглавие : Biodistribution of nanodiamonds in the body of mice using EPR spectrometry
Колич.характеристики :5 с
Коллективы : Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR) [16-04-00999]
Место публикации : IET Sci. Meas. Technol.: INST ENGINEERING TECHNOLOGY-IET, 2019. - Vol. 13, Is. 7. - С. 984-988. - ISSN 1751-8822, DOI 10.1049/iet-smt.2018.5594. - ISSN 1751-8830(eISSN)
Примечания : Cited References:32. - This work was supported by the Russian Foundation for Basic Research (project no. 16-04-00999).
Предметные рубрики: DRUG-DELIVERY
DETONATION NANODIAMONDS
NANOMATERIALS
DOXORUBICIN
Аннотация: In vitro experiments proved the usefulness of electron paramagnetic resonance (EPR) spectrometry for detecting detonation nanodiamonds (NDs) in samples of biomaterials (blood and homogenates of organs of mice). A characteristic EPR signal (g = 2.003, Delta H similar or equal to 10 G) was detected in biomaterials containing NDs, and its intensity linearly increased at nanoparticle concentrations of between 1.6 and 200 mu g/ml. In vivo experiments demonstrated that EPR spectrometry was effective for monitoring the inter-organ distribution of NDs intravenously injected to mice. In 2.5 h after the injection of NDs, the nanoparticles mainly accumulated in the lungs and liver of the animals - about 25 and 20%, respectively, of the initially injected NDs. The amounts of NDs accumulated in the heart and kidneys were considerably lower. Also, EPR spectrometry did not detect NDs in the blood, spleen, brain, and femoral muscles of mice. Ten days after injection, EPR spectrometry detected redistribution of NDs in mice. The amounts of nanoparticles decreased approximately by a factor of 3.5 in the lungs and increased almost by a factor of 3 in the liver; NDs were detected in the spleen. This study suggests ways to use EPR spectrometry to study the distribution, accumulation, and elimination of detonation NDs injected into laboratory animals.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Mogilnaya O. A., Ronzhin N. O., Artemenko K. S., Bondar V. S.
Заглавие : Creation of Bifunctional Indicating Complex Based on Nanodiamonds and Extracellular Oxidases of Luminous Fungus Neonothopanus nambi
Колич.характеристики :4 с
Место публикации : Dokl. Biochem. Biophys.: MAIK NAUKA/INTERPERIODICA/SPRINGER, 2018. - Vol. 480, Is. 1. - С. 135-138. - ISSN 1607-6729, DOI 10.1134/S160767291803002X. - ISSN 1608-3091(eISSN)
Примечания : Cited References:13
Предметные рубрики: PHANEROCHAETE-CHRYSOSPORIUM
NANOPARTICLES
Аннотация: A bifunctional indicating complex was created by immobilization of extracellular oxidases (glucose oxidase and peroxidases) of luminous fungus Neonothopanus nambi onto modified nanodiamonds (MNDs) synthesized by detonation. It was found that the enzymes firmly adsorb onto MND particles and exhibit their catalytic activity. Model in vitro experiments showed that the created MND-enzymes complex is suitable for repeated use for analyte (glucose and phenol) testing and retains its activity after storage at 4 degrees C in deionized water for 1 month. The data obtained offer the prospects for developing a new class of reusable multifunctional indicating and diagnostic test systems on the basis of MNDs and higher fungal enzymes for medical and ecological analytics.
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10.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Puzyr' A.P., Pozdnyakova I.O., Bondar' V.S.
Заглавие : Design of a luminescent biochip with nanodiamonds and bacterial luciferase
Колич.характеристики :3 с
Место публикации : Phys. Solid State: AMER INST PHYSICS, 2004. - Vol. 46, Is. 4. - С. 761-763. - ISSN 1063-7834, DOI 10.1134/1.1711469
Примечания : Cited References: 10
Аннотация: An "aluminum oxide film-adhesive layer-nanodiamond-luciferase" supramolecular structure is prepared on a flat plate. It is demonstrated that, in this structure, the enzyme retains the catalytic activity. The structure prepared can be treated as a luminescent biochip prototype for use in bioluminescent analysis. (C) 2004 MAIK "Nauka / Interperiodica".
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11.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Ronzhin N. O., Baron A. V., Bondar V. S., Gitelson I. I.
Заглавие : Designing a reusable system based on nanodiamonds for biochemical determination of urea
Место публикации : Doklad. Biochem. Biophys. - 2015. - Vol. 465, Is. 1. - С. 428-431. - ISSN 16076729 (ISSN) , DOI 10.1134/S1607672915060216
Аннотация: A reusable system including urease covalently bound to the surface of modified nanodiamonds (MNDs) has been developed for the multiple determination of urea. The immobilized enzyme exhibits functional activity and catalyzes the hydrolysis of urea to yield ammonia. The presence of ammonia is confirmed by the formation of a colored product after the addition of chemical reagents. It was shown that the MNDs-urease complex can function in a wide range of temperatures and pH as well as in deionized water. The complex provides a linear yield of the product at low analyte concentrations and allows the multiple determination of urea in vitro. © 2015, Pleiades Publishing, Ltd.
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12.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Puzyr A.P., Neshumayev D.A., Tarskikh S.V., Makarskaya G.V., Dolmatov V.Y., Bondar V.S.
Заглавие : Destruction of human blood cells in interaction with detonation nanodiamonds in experiments in vitro
Колич.характеристики :4 с
Место публикации : Diam. Relat. Mat.: ELSEVIER SCIENCE SA, 2004. - Vol. 13: 9th International Conference on New Diamond Science and Technology (MAR 26-29, 2004, Tokyo, JAPAN), Is. 11.12.2013. - С. 2020-2023. - ISSN 0925-9635, DOI 10.1016/j.diamond.2004.06.003
Примечания : Cited References: 10
Ключевые слова (''Своб.индексиров.''): nanodiamonds--white blood cells--erythrocytes--chemiluniscence
Аннотация: In experiments in vitro on human blood, it was shown that nanodianiond (ND) particles change the kinetics of active oxygen generation (AOG), causing white cell destruction and erythrocyte hemolysis. Various mechanisms of the observed effects have been considered. Nanodianionds adapted for biological research and possessing higher colloidal stability make it possible to obtain sterile hydrosols and mixtures with drugs and are more preferable for medical -biological research. We discussed the necessity of experiments in vivo and showed the first results of injection of the adapted nanodianionds to the laboratory animals. (C) 2004 Elsevier B.V. All rights reserved.
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13.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Puzyr A.P., Neshumaev D.A., Tarskikh S.V., Makarskaya G.V., Dolmatov V.Y., Bondar V.S.
Заглавие : Destruction of human blood cells upon interaction with detonation nanodiamonds in experiments in vitro
Колич.характеристики :6 с
Место публикации : Biofizika: MEZHDUNARODNAYA KNIGA, 2005. - Vol. 50, Is. 1. - С. 101-106. - ISSN 0006-3029
Примечания : Cited References: 15
Ключевые слова (''Своб.индексиров.''): nanodiamonds--blood--erythrocytes--leukocytes--monocytes-lymphocytes--neutrophils--chemiluminescence
Аннотация: The influence of nanodiamonds synthesized by detonation on human red and white blood cells in vitro was studied. Nine nanodiamond samples produced by different manufacturers and two samples of modified nanodiamonds with high colloidal stability were used in the study. It was shown that nanoparticles cause the destruction of white cells and the hemolysis of erythrocytes. Possible mechanisms of the desctructive effect of detonation nanodiamonds on blood-forming elements are discussed.
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14.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Puzyr A.P., Neshumaev D.A., Tarskikh S.V., Makarskaya G.V., Dolmatov V.Y., Bondar V.S.
Заглавие : Destruction of human blood cells upon interaction with detonation nanodiamonds in experiments in vitro
Колич.характеристики :6 с
Место публикации : Biofizika: MEZHDUNARODNAYA KNIGA, 2005. - Vol. 50, Is. 1. - P101-106. - ISSN 0006-3029
Примечания : Cited References: 15
Ключевые слова (''Своб.индексиров.''): nanodiamonds--blood--erythrocytes--leukocytes--monocytes-lymphocytes--neutrophils--chemiluminescence
Аннотация: The influence of nanodiamonds synthesized by detonation on human red and white blood cells in vitro was studied. Nine nanodiamond samples produced by different manufacturers and two samples of modified nanodiamonds with high colloidal stability were used in the study. It was shown that nanoparticles cause the destruction of white cells and the hemolysis of erythrocytes. Possible mechanisms of the desctructive effect of detonation nanodiamonds on blood-forming elements are discussed.
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15.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Inzhevatkin E. V., Baron A. V., Maksimov N. G., Volkova M. B., Puzyr A. P., Bondar V. S.
Заглавие : Detection of nanodiamonds in biological samples by EPR spectrometry
Место публикации : Doklad. Biochem. Biophys.: Maik Nauka Publishing / Springer SBM, 2017. - Vol. 477, Is. 1. - С. 394-397. - ISSN 16076729 (ISSN) , DOI 10.1134/S1607672917060138
Аннотация: In model experiments in vitro, the applicability of the EPR spectrometry method for the detection of modified nanodiamonds (MNDs) in blood and homogenates of mouse organs has been established. A characteristic signal (g = 2.003, ?H ? 10 G) is observed in the samples of biomaterials containing MNDs, the intensity of which increases linearly with the concentration of nanoparticles in the range of 1.6–200 ?g MNDs per 1 mL of the sample. The EPR method in biomaterials reveals the presence of intrinsic paramagnetic centers, signals from which are superimposed on the signal from the MNDs. However, the intensity of these signals is small, which makes it possible to register the MNDs using EPR spectrometry with the necessary accuracy. The data obtained open up the prospects of using the EPR method for studies of the interorgan distribution, accumulation, and elimination of MNDs during their intravenous injection into experimental animals. © 2017, Pleiades Publishing, Ltd.
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16.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Ronzhin, Nikita, Puzyr, Alexey, Bondar, Vladimir
Заглавие : Detonation Nanodiamonds as a New Tool for Phenol Detection in Aqueous Medium
Колич.характеристики :6 с
Коллективы : Russian Academy of Sciences [0356-2016-0709]; Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology [16-43-243027]
Место публикации : J. Nanosci. Nanotechnol.: AMER SCIENTIFIC PUBLISHERS, 2018. - Vol. 18, Is. 8. - С. 5448-5453. - ISSN 1533-4880, DOI 10.1166/jnn.2018.15382. - ISSN 1533-4899(eISSN)
Примечания : Cited References:27. - This work was supported by the state budget allocated to the fundamental research at the Russian Academy of Sciences (Project No. 0356-2016-0709) and Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research (Project No. 16-43-243027).
Предметные рубрики: ENVIRONMENTAL-POLLUTANTS
DRUG-DELIVERY
PARTICLES
CARBON
Ключевые слова (''Своб.индексиров.''): detonation nanodiamonds--catalytic activity--metal ions--azo coupling--reaction--phenol detection
Аннотация: This paper demonstrates the effectiveness of using detonation nanodiamonds (DNDs) for detecting phenol in aqueous medium. The study has shown that the catalytic effect of DNDs in the oxidative azo coupling reaction (phenol-4-aminoantipyrine-hydrogen peroxide) is produced by trace amounts of iron and copper ions adsorbed on the surface of nanoparticles. The effectiveness of DNDs as a catalyst is determined by the amounts of these adsorbates and can be enhanced by a factor of two by additional adsorption of these ions onto the nanoparticles. A rise in the temperature of the ONO-catalyzed azo coupling reaction leads to a considerable (4.5-fold) increase in the reaction product yield. DNDs used to detect phenol in aqueous medium enable a linear increase in the yield of the product of the azo coupling reaction at concentrations of the analyte of between 0.05 and 10 mu g/mlThe study demonstrates that DNDs can be reused to detect phenol in water samples.
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17.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Mikheev G.M., Vanyukov V.V., Mogileva T.N., Puzyr' A.P., Bondar' V.S., Svirko Y.P.
Заглавие : Effect of laser-radiation polarization on the nonlinear scattering of light in nanodiamond suspensions
Колич.характеристики :5 с
Коллективы : Russian Foundation for Basic Research [13-02-96016r_ural_a]; Presidium of the Ural Branch of the Russian Academy of Sciences [12-S-1-1003]; Academy of Finland [278252]
Место публикации : Tech. Phys. Lett.: MAIK NAUKA/INTERPERIODICA/SPRINGER, 2014. - Vol. 40, Is. 7. - С. 609-613. - ISSN 1063-7850, DOI 10.1134/S1063785014070220. - ISSN 1090-6533
Примечания : Cited References: 19. - This study was supported in part by the Russian Foundation for Basic Research (project no. 13-02-96016r_ural_a), the Presidium of the Ural Branch of the Russian Academy of Sciences (project no. 12-S-1-1003), and the Academy of Finland (grant no. 278252).
Предметные рубрики: CARBON NANOTUBE SUSPENSIONS
DETONATION NANODIAMOND
OPTICAL-PROPERTIES
Аннотация: The effect of laser radiation polarization on the nonlinear scattering of light in aqueous suspensions of detonation nanodiamonds (DNDs) in a regime of optical power limiting (OPL) has been studied. It is established that the nonlinear transmission coefficient of DND suspension in the OPL regime in a field of nanosecond laser pulses with a wavelength of 532 nm is independent of the polarization of incident radiation. The nonlinear scattering of light observed at an angle of 90A degrees in the plane perpendicular to the plane of polarization of the incident radiation depends on the polarization angle in accordance with a trigonometric law. It is shown that the ratio of the signals of scattered radiation for the vertical and horizontal polarizations exhibits nonmonotonic dependence on the laser-beam power density. The results are explained by the Rayleigh-Mie scattering and a change in the size of scattering centers as a result of the effect of a laser upon the DND suspension.
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18.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Baron A.V., Puzyr A.P., Baron I.I., Bondar V.S.
Заглавие : Effects of Modified Detonation Nanodiamonds on the Biochemical Composition of Human Blood
Колич.характеристики :4 с
Место публикации : Bull. Exp. Biol. Med.: SPRINGER, 2013. - Vol. 154, Is. 6. - С. 781-784. - ISSN 0007-4888, DOI 10.1007/s10517-013-2055-y
Примечания : Cited References: 14
Предметные рубрики: PARTICLES
Ключевые слова (''Своб.индексиров.''): modified nanodiamonds--blood serum
Аннотация: In vitro experiments showed that protein and non-protein components of human blood serum could be absorbed on the surface of modified nanodiamonds obtained by detonation synthesis. The prospects of using nanodiamond as a new absorbent for hemodialysis, plasmapheresis, and laboratory diagnostics are discussed.
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19.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Prokhorenkov V. I., Vasil’eva E. Y., Puzyr’ A. P., Bondar’ V. S.
Заглавие : Effects of Nanodiamonds of Explosive Synthesis on the Skin of Experimental Animals Locally Exposed to Cobalt and Chrome Ions
Место публикации : Bull. Exp. Biol. Med. - 2014. - Vol. 158, Is. 2. - С. 264-267. - ISSN 00074888 (ISSN) , DOI 10.1007/s10517-014-2737-0
Ключевые слова (''Своб.индексиров.''): allergic contact dermatitis--chrome--cobalt--ions of bivalent metals--nanodiamonds--chromium--cobalt--nanodiamond--adsorption--animal--chemistry--dermatitis, allergic contact--drug effects--guinea pig--nonparametric test--skin--adsorption--animals--chromium--cobalt--dermatitis, allergic contact--guinea pigs--nanodiamonds--skin--statistics, nonparametric
Аннотация: Experiments in vivo demonstrated the protective effect of modified nanodiamonds on guinea pig skin after local exposure cobalt ions, but not chrome ions. The observed differences are determined by different adsorption of these ions by nanodiamonds: in vitro experiments showed that nanodiamonds adsorbed cobalt ions, but not chrome ions from water solutions. The perspectives of using modified nanodiamonds as a new adsorbent for prevention of allergic contact dermatitis induced by ions of bivalent metals are discussed. © 2014, Springer Science+Business Media New York.
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20.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Inzhevatkin E. V., Baron A. V., Maksimov N. G., Volkova M. B., Puzyr A. P., Bondar V. S.
Заглавие : EPR Spectrometric Estimation of the Distribution of Intravenously Injected Nanodiamonds in Mice
Колич.характеристики :7 с
Коллективы : Russian Foundation for Basic Research [16-04-00999]
Место публикации : Biol. Bull: PLEIADES PUBLISHING INC, 2019. - Vol. 46, Is. 3. - С. 277-283. - ISSN 1062-3590, DOI 10.1134/S1062359019020079. - ISSN 1608-3059(eISSN)
Примечания : Cited References:56. - This work was supported by the Russian Foundation for Basic Research, project no. 16-04-00999.
Предметные рубрики: DRUG-DELIVERY
DETONATION NANODIAMONDS
NANOMATERIALS
PARTICLES
Аннотация: The distribution in mice of intravenously injected modified nanodiamonds (MNDs) obtained by detonation synthesis was studied using electron paramagnetic resonance (EPR) spectrometry. It has been shown that 2.5 h after MND injection into the tail vein of mice, the nanoparticles accumulate mainly in the lungs and liver of animals; much smaller amounts of nanoparticles were found in the kidneys and heart. The presence of MNDs in the samples of blood, spleen, brain, and thigh muscles of mice was not detected within the sensitivity of the method used.
WOS,
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