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Destruction of human blood cells in interaction with detonation nanodiamonds in experiments in vitro [Text] / A. P. Puzyr [et al.] // Diam. Relat. Mat. - 2004. - Vol. 13: 9th International Conference on New Diamond Science and Technology (MAR 26-29, 2004, Tokyo, JAPAN), Is. 11.12.2013. - P2020-2023, DOI 10.1016/j.diamond.2004.06.003. - Cited References: 10
. - ISSN 0925-9635РУБ Materials Science, Multidisciplinary
Кл.слова (ненормированные):
nanodiamonds -- white blood cells -- erythrocytes -- chemiluniscence
Аннотация: In experiments in vitro on human blood, it was shown that nanodianiond (ND) particles change the kinetics of active oxygen generation (AOG), causing white cell destruction and erythrocyte hemolysis. Various mechanisms of the observed effects have been considered. Nanodianionds adapted for biological research and possessing higher colloidal stability make it possible to obtain sterile hydrosols and mixtures with drugs and are more preferable for medical -biological research. We discussed the necessity of experiments in vivo and showed the first results of injection of the adapted nanodianionds to the laboratory animals. (C) 2004 Elsevier B.V. All rights reserved.
Держатели документа:
Russian Acad Sci, Siberian Branch, Inst Biophys, Krasnoyarsk, Russia
Russian Acad Sci, Siberian Branch, Dept Immunol, KSC, Krasnoyarsk, Russia
JSC, Diamond Ctr, Sci Prod Dept, St Petersburg 192076, Russia
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50
Доп.точки доступа:
Puzyr, A.P.; Neshumayev, D.A.; Tarskikh, S.V.; Makarskaya, G.V.; Dolmatov, V.Y.; Bondar, V.S.
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