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полный	информационный	краткий

Поисковый запрос: (<.>K=Therapeutics<.>)

Общее количество найденных документов : 1

Polyhydroxyalkanoates (PHA) for therapeutic applications / J. Y. Zhang [et al.] // Mater. Sci. Eng. C-Mater. Biol. Appl. - 2018. - Vol. 86. - P144-150, DOI 10.1016/j.msec.2017.12.035. - Cited References:105. - This research was financially supported by a grant from Ministry of Sciences and Technology (Grant No. 2016YFB0302504); grants from National Natural Science Foundation of China (Grant No. 31430003, 31600072 and 81503079); a grant from Natural Science Foundation of Jiangxi Province (Grant No. 20161BAB215204); and a grant from Russian Science Foundation (Grant No. 17-15-01352). Tsinghua President Fund also supported this project (Grant No. 2015THZ10). . - ISSN 0928-4931. - ISSN 1873-0191

РУБ Materials Science, Biomaterials
Рубрики:
TISSUE ENGINEERING APPLICATIONS
3-HYDROXYBUTYRATE METHYL-ESTER
Кл.слова (ненормированные):
PHA -- Therapeutics -- Tissue engineering -- Implants -- Drug delivery -- Biomedicine
Аннотация: As intracellular carbon and energy storage materials, polyhydroxyalkanoates (PHA) are a diverse biopolyesters synthesized by many bacteria. PHA have been produced in large quantity for various application research including medical implants for approximately 30 years. Many studies demonstrated that PHA are promising implant materials due to their diverse and ascendant mechanical, biodegradable and tissue compatible properties. Importantly, common PHA biodegradation products including oligomers and monomers are also not toxic to the cells and tissues. Pharmaceutical applications of some PHA degradation products also have been reported. So far, no study has been reported to have any carcinogenesis result induced by any PHA or their biodegradation products. All results suggest that PHA could be developed into various bio-implant products.

WOS,
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Держатели документа:
Nanchang Univ, Inst Life Sci, Lab Fear & Anxiety Disorders, Nanchang 330031, Jiangxi, Peoples R China.
Siberian Fed Univ, Krasnoyarsk 660041, Russia.
Tsinghua Univ, Sch Life Sci, MOE Key Lab Bioinformat, Beijing 100084, Peoples R China.
Russian Acad Sci, Inst Biophys, Siberian Branch, Krasnoyarsk 660036, Russia.
Univ Sao Paulo, Inst Ciencias Biomed, Dept Microbiol, BR-05509900 Sao Paulo, Brazil.

Доп.точки доступа:
Zhang, Junyu; Shishatskaya, Ekaterina I.; Volova, Tatiana G.; da Silva, Luiziana Ferreira; Chen, Guo-Qiang; Ministry of Sciences and Technology [2016YFB0302504]; National Natural Science Foundation of China [31430003, 31600072, 81503079]; Natural Science Foundation of Jiangxi Province [20161BAB215204]; Russian Science Foundation [17-15-01352]; Tsinghua President Fund [2015THZ10]

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