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Каталог книг и продолжающихся изданий библиотеки Института биофизики СО РАН (4)

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A new approach to the study of the statistical properties of gene sequences / A. N. Gorban' [et al.] // Biophysics. - 1993. - Vol. 38, Is. 5. - P. 783-787 . - ISSN 0006-3509
Аннотация: An essentially new method is proposed for studying the statistical properties of gene sequences (g.s.) based on construction of a frequency-correlation dictionary (f.c.d.) for the g.s. being investigated (the f.c.d. is the set of all subsequences (words) with a length from 1 to N together with the frequencies of their encounter in the g.s. studied). It is shown that a measure of the redundancy of the g.s. is the characteristic length of the word d* starting from which all the words in the g.s. are unique, i.e. have the frequency 1. В© 1994.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Division, the Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Computational Centre, the Siberian Division, the Russian Academy of Sciences, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Gorban', A.N.; Mirkes, Ye.M.; Popova, T.G.; Sadovskii, M.G.

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INTRONS DIFFER FROM EXONS BY THEIR REDUNDANCY [Текст] / T. G. POPOVA, M. G. SADOVSKII // Genetika. - 1995. - Vol. 31, Is. 10. - P. 1365-1369. - Cited References: 12 . - ISSN 0016-6758

РУБ Genetics & Heredity
Рубрики:
SEQUENCES
DNA
Аннотация: This paper is devoted to an analysis of the intrinsic structure of the gene from the point of view of the redundancy of different structural units - exons and introns. Human genes for which the exon-intron structure has - been clearly established were Studied. The redundancy of each exon and intron in the gene was determined. It was shown that, in human genes, introns are more redundant than exons. Redundancy is determined as the smallest length of a word (oligonucleotide) beginning with which all words in the studied nucleotide sequence are found exactly once. Mechanisms leading to the disruption of the general pattern of ratios of redundancy of exons and introns are studied.

WOS : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
POPOVA, T.G.; SADOVSKII, M.G.

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REDUNDANCY OF EUKARYOTIC DNA DECREASES AFTER EXCISION OF INTRONS [Text] / T. G. POPOVA, M. G. SADOVSKII // Mol. Biol. - 1995. - Vol. 29, Is. 3. - P. 281-285. - Cited References: 23 . - ISSN 0026-8933

РУБ Biochemistry & Molecular Biology
Рубрики:
SEQUENCES
Кл.слова (ненормированные):
EXON -- INTRON -- WORD -- FREQUENCY -- REDUNDANCY
Аннотация: The article is devoted to analysis of the internal gene structure with respect to redundancy of exons and introns. Human genes with precisely determined exon-intron structure were studied. Redundancy of each exon and intron within a certain gene was measured. In the analyzed human genes, introns were more redundant than exons. Redundancy was determined as the minimal length of a word (oligonucleotide) that is present as a single copy within the nucleotide sequence studied. Mechanisms are discussed that lead to disturbances in the relationships found between the redundancies of exons and introns.

WOS : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
POPOVA, T.G.; SADOVSKII, M.G.

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