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1.


   
    Actinides and other radionuclides in sediments and submerged plants of the Yenisei River / A. Bolsunovsky, L. Bondareva // Journal of Alloys and Compounds. - 2007. - Vol. 444-445, Is. SPEC. ISS. - P495-499, DOI 10.1016/j.jallcom.2007.01.146 . - ISSN 0925-8388
Кл.слова (ненормированные):
Accumulation -- Actinides in aquatic plants and sediments -- Radiochemical and ?-spectrometric investigations -- Sequential extraction technique -- Yenisei River -- Actinides -- Bioaccumulation -- Plants (botany) -- Radioisotopes -- Rivers -- Sampling -- Sediments -- Mining-and-Chemical combine (MCC) -- Radiochemical and spectrometric investigations -- Sediment samples -- Sequential extraction techniques -- Contamination
Аннотация: The source of radioactive contamination of the Yenisei River floodplain, including contamination with actinides, is the Mining-and-Chemical combine (MCC), which has for many years been producing weapons-grade plutonium. Actinides have been detected not only in the soil and sediment of the river but also in the biomass of aquatic plants. The aim of our investigation was to assess the levels of actinides and other radionuclides in sediments and aquatic plants both near the MCC and at a considerable distance from it, down the Yenisei River. Investigations of the Yenisei River sediment samples revealed high activity concentrations of actinides (Pu isotopes and 241Am), which were 100 times higher than their global fallout levels. Sequential extraction of radionuclides from samples of sediments collected near the MCC showed that the amounts of extracted 241Am were the largest (up to 98% of initial activity). It was found that aquatic plants of the Yenisei River collected both near the MCC discharge site and at a distance up to 200 km downstream contained several actinide isotopes. The aquatic moss, Fontinalis antipyretica, was found to contain higher levels of radionuclides than Potamogeton lucens. Leaves of P. lucens contained higher levels of radionuclides, including 239Np, than stems. Sequential extraction of radionuclides from samples of aquatic plants showed that 239Np levels in exchangeable and adsorption fractions of P. lucens biomass were higher than in the respective fractions of F. antipyretica biomass. В© 2007 Elsevier B.V. All rights reserved.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Branch, the Russian Academy of Sciences, Krasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Bolsunovsky, A.; Bondareva, L.

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2.


   
    Accumulation and release of 241Am by a macrophyte of the Yenisei River (Elodea canadensis) / A. Bolsunovsky, T. Zotina, L. Bondareva // Journal of Environmental Radioactivity. - 2005. - Vol. 81, Is. 1. - P33-46, DOI 10.1016/j.jenvrad.2004.10.012 . - ISSN 0265-931X
Кл.слова (ненормированные):
241Am -- Accumulation -- Laboratory experiments -- Release -- Submerged plant Elodea canadensis -- Yenisei River -- Activation analysis -- Biomass -- Concentration (process) -- Effluents -- Plutonium -- Rivers -- Aquatic plants -- Elodea plant -- Macrophytes -- Radioactive contamination -- Transuranium elements -- americium 241 -- river water -- americium -- americium nitrate -- bioaccumulation -- biological uptake -- macrophyte -- pollutant source -- radioactive pollution -- river water -- submerged vegetation -- article -- biomass -- concentration (parameters) -- environmental factor -- fractionation -- laboratory -- macrophyte -- radioactivity -- river -- sampling -- adsorption -- chemistry -- Hydrocharitaceae -- methodology -- physiology -- plant -- radiation exposure -- radiation monitoring -- Russian Federation -- sediment -- soil pollutant -- time -- tissue distribution -- water pollutant -- Eastern Hemisphere -- Eurasia -- Russian Federation -- World -- Yenisei River -- Elodea canadensis -- Adsorption -- Americium -- Biomass -- Chemical Fractionation -- Geologic Sediments -- Hydrocharitaceae -- Plant Shoots -- Radiation Monitoring -- Rivers -- Russia -- Soil Pollutants, Radioactive -- Time Factors -- Tissue Distribution -- Water Pollutants, Radioactive
Аннотация: The source of radioactive contamination of the Yenisei River floodplain, including contamination with transuranic elements, is the Mining-and-Chemical Combine of the Russian Ministry of Atomic Energy, which has for many years been producing weapons-grade plutonium. Transuranic elements have been detected not only in the soil and sediment of the river but also in the biomass of aquatic plants. This work is an investigation of accumulation and release of 241Am by a submerged macrophyte of the Yenisei River (Elodea canadensis) in laboratory experiments. In 2000-2003, laboratory experiments were carried out with biomass of E. canadensis Mich. and filtered river water. The samples were collected from the Yenisei River upstream of the discharge of the Combine's radioactive effluent. The experiments showed that 241Am is accumulated by Elodea biomass: the activity concentration of 241Am can reach 3280 В± 240 Bq/g, with the concentration factor for 241Am 16 600 В± 2200 l/kg. Results of chemical fractionation have proved that in the course of 241Am accumulation by Elodea biomass, 241Am tightly bound to biomass increases from 11% to 27% of the total 241Am in the biomass. Release of 241Am from the decaying Elodea biomass has been evaluated experimentally. By the end of the experiment (lasting up to 127 days), the Elodea plants had lost up to 65% of their initial 241Am activity and the rate of 241Am release into the water environment reached 23 Bq/day. В© 2004 Elsevier Ltd. All rights reserved.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk 660036, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Bolsunovsky, A.; Zotina, T.; Bondareva, L.

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3.


   
    Experimental investigations of the intensity of phosphorus radionuclide uptake by samples of algobacterial community of the Yenisei River / A. Ya. Bolsunovskij, S. V. Kosinenko // Radiatsionnaya Biologiya. Radioekologiya. - 2001. - Vol. 41, Is. 1. - С. 119-123 . - ISSN 0869-8031
Кл.слова (ненормированные):
phosphorus -- alga -- article -- bacterium -- microbiology -- radiation exposure -- Russian Federation -- water pollution -- Algae -- Bacteria -- Phosphorus Radioisotopes -- Siberia -- Water Microbiology -- Water Pollution, Radioactive -- Algae -- Ecosystems -- Phosphorus -- Radioactivity -- Radioisotopes -- River pollution -- Algobacterial community -- Radioecological concentration -- Yenisei River -- Biological radiation effects
Аннотация: The experiments in which phosphorus radionuclide was added to samples of algobacterial community of the Yenisei River taken near the production area of the Mining-and-Chemical Combine (Zheleznogorsk) made possible determining the uptake rates and coefficients of radionuclide accumulation by microorganisms. Radios between processes of adsorption and accumulation of phosphorus radionuclide by components of water seston (suspended matter) have been determined. The portion of the specific radioactivity of phosphorus adsorbed by unit mass of seston (and algae) has been found to be not more than 7% of the activity accumulated by algal cells.

Scopus
Держатели документа:
Inst. of Biophysics, Siberian Branch, RAS, Krasnoyarsk, 660036, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Bolsunovskij, A.Ya.; Kosinenko, S.V.

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4.


   
    Growth and bioluminescence of luminous bacteria under the action of aflatoxin B1 before and after its treatment with nanodiamonds [Text] / O. A. Mogilnaya, A. P. Puzyr', V. S. Bondar' // Appl. Biochem. Microbiol. - 2010. - Vol. 46, Is. 1. - P33-37, DOI 10.1134/S0003683810010059. - Cited References: 24. - This work was supported by a grant of the Russian Foundation for Basic Research and the National Scientific Fund of the United States no. 06-04-90234. . - ISSN 0003-6838
РУБ Biotechnology & Applied Microbiology + Microbiology
Рубрики:
B-1
   MYCOTOXINS

   ADSORPTION

   FOOD

Аннотация: The effect of aflatoxin B1 on growth and luminescence of marine luminous bacteria P. phosphoreum and recombinant E. coli Z905 cells was investigated. The bidirectional effect of aflatoxin B1 on the studied bacterial species was detected-an inhibition of luminescence in P. phosphoreum and its stimulation in E. coli. It was shown that aflatoxin B1 influences the cell luminescence in the freshly grown cultures and bacteria restored after lyophilization. It was detected that the effect of aflatoxin B1 was graded after interaction with the modified nanodiamond (MND) of detonation synthesis. After mycotoxin's treatment with MND, it does not cause significant changes in bacterial luminescence. The possibilities for the use of P. phosphoreum and E. coli bacteria in the bioluminescent monitoring of aflatoxin B1 and the use of MND for mycotoxin deactivation are discussed.

Держатели документа:
[Mogilnaya, O. A.
Puzyr', A. P.
Bondar', V. S.] Russian Acad Sci, Inst Biophys, Siberian Branch, Krasnoyarsk 660036, Russia
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Mogilnaya, O.A.; Puzyr', A.P.; Bondar', V.S.

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5.


   
    Hematological Parameters and the State of Liver Cells of Rats After Oral Administration of Aflatoxin B1 Alone and Together with Nanodiamonds [Text] / O. A. Mogilnaya [et al.] // Nanoscale Res. Lett. - 2010. - Vol. 5, Is. 5. - P908-912, DOI 10.1007/s11671-010-9571-8. - Cited References: 23. - The study was financially supported by the Russian Foundation for Basic Research (RFBR) (Grant No. 06-0490234) and the RAS Presidium (Program No. 27, Project No. 64). . - ISSN 1931-7573
РУБ Nanoscience & Nanotechnology + Materials Science, Multidisciplinary + Physics, Applied
Рубрики:
B-1
   MYCOTOXINS

   ADSORPTION

Кл.слова (ненормированные):
Nanodiamonds -- Aflatoxin B(1) -- Detoxification -- Adsorbent
Аннотация: Hematological parameters and the state of liver cells of rats were examined in vivo after the animals received aflatoxin B(1) (AfB(1)) alone and together with modified nanodiamonds (MND) synthesized by detonation. The rats that had received the MND hydrosol had elevated leukocyte levels, mainly due to higher granulocyte counts and somewhat increased monocyte counts compared to control rats. Hematological parameters of the rats that had received AfB(1) alone differed from those of the control rats in another way: total white blood cell counts were significantly lower due to the decreased lymphocyte counts. In rats that had consumed AfB(1) with the MND hydrosol, changes in hematological parameters were less pronounced than in rats that had consumed either AfB(1) or MND. Electron microscopy showed that hepatocytes of the rats that had received the MND hydrosol or AfB(1) with the MND hydrosol contained elevated levels of lipid inclusions and lysosomes. Hyperplasia of the smooth endoplasmic reticulum (EPR) was revealed in liver specimens of the rats that had received AfB(1). Results of the study suggest the conclusion about mutual mitigation of the effects of nanoparticles and the mycotoxin on rats blood and liver cells after AfB(1) has adsorbed on MND.

Держатели документа:
[Mogilnaya, O. A.
Puzyr, A. P.
Bondar, V. S.] Inst Biophys SB RAS, Krasnoyarsk 660036, Russia
[Baron, A. V.] Siberian Fed Univ, Inst Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Mogilnaya, O.A.; Puzyr, A.P.; Baron, A.V.; Bondar, V.S.

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6.


   
    Nanodiamonds as Carriers for Address Delivery of Biologically Active Substances [Text] / K. V. Purtov [et al.] // Nanoscale Res. Lett. - 2010. - Vol. 5, Is. 3. - P631-636, DOI 10.1007/s11671-010-9526-0. - Cited References: 24. - This work was supported by the Program # 27 for Basic Research of the Presidium of RAS (project 3.6.3). . - ISSN 1931-7573
РУБ Nanoscience & Nanotechnology + Materials Science, Multidisciplinary + Physics, Applied
Рубрики:
ANTICANCER DRUGS
   NANOPARTICLES

   ADSORPTION

   PARTICLES

   PROTEINS

Кл.слова (ненормированные):
Nanodiamonds -- Ligand -- Protein immobilization -- Nanocarrier -- Targeted delivery
Аннотация: Surface of detonation nanodiamonds was functionalized for the covalent attachment of immunoglobulin, and simultaneously bovine serum albumin and Rabbit Anti-Mouse Antibody. The nanodiamond-IgG(I125) and RAM-nanodiamond-BSA(I125) complexes are stable in blood serum and the immobilized proteins retain their biological activity. It was shown that the RAM-nanodiamond-BSA(I125) complex is able to bind to the target antigen immobilized on the Sepharose 6B matrix through antibody-antigen interaction. The idea can be extended to use nanodiamonds as carriers for delivery of bioactive substances (i.e., drugs) to various targets in vivo.

Держатели документа:
[Purtov, K. V.
Puzyr, A. P.
Bondar, V. S.] SB RAS, Inst Biophys, Krasnoyarsk, Russia
[Petunin, A. I.] Med Res Co Dias, Krasnoyarsk, Russia
[Burov, A. E.] SB RAS, Inst Computat Modeling, Krasnoyarsk, Russia
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Purtov, K.V.; Petunin, A.I.; Burov, A.E.; Puzyr, A.P.; Bondar, V.S.

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7.


   
    The adsorption of aflatoxin B1 by detonation-synthesis nanodiamonds [Text] / A. P. Puzyr [et al.] // Dokl. Biochem. Biophys. - 2007. - Vol. 417, Is. 1. - P299-301, DOI 10.1134/S1607672907060026. - Cited References: 15 . - ISSN 1607-6729
РУБ Biochemistry & Molecular Biology + Biophysics
Рубрики:
TOXICITY

Держатели документа:
[Puzyr, A. P.
Purtov, K. V.
Bondar, V. S.] Russian Acad Sci, Inst Biophys, Siberian Div, Krasnoyarsk 660036, Russia
[Luo, M.
Brenner, D. W.] N Carolina State Univ, Dept Mat Sci & Engn, Raleigh, NC 27695 USA
[Shenderova, O. A.] Int Technol Ctr, Raleigh, NC USA
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Puzyr, A.P.; Purtov, K.V.; Shenderova, O.A.; Luo, M...; Brenner, D.W.; Bondar, V.S.

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8.


   
    Physical and chemical properties of modified nanodiamonds [Text] / A. P. Puzyr [et al.] ; ed.: DM Gruen, OA Shenderova, erova, OA She // Synthesis, Properties and Applications of Ultrananocrystalline Diamond. Ser. NATO SCIENCE SERIES, SERIES II: MATHEMATICS, PHYSICS AND CHEMISTRY : SPRINGER, 2005. - Vol. 192: NATO Advanced Research Workshop on Synthesis, Properties and Applications of Ultrananocrystalline Diamond (JUN 07-10, 2004, St Petersburg, RUSSIA). - P261-270. - Cited References: 15 . - ISBN 1-4020-3320-6
РУБ Chemistry, Physical + Materials Science, Multidisciplinary

Кл.слова (ненормированные):
nanodiamond -- modified nanodiamonds -- hydrosols -- colloidal stability -- electrophoresis -- powder fractioning -- precursors for CVD -- electron field emission
Аннотация: A unique technology of nanodiamond surface modification is suggested which allows to separation of commercial nanodiamond powders into two fractions (F1 and 172), each possessing absolutely new properties as compared to the initial powder. F1 and F2 differ in size characteristics. Initial and modified nanodiamonds contain iron impurities and two types of nondiamond carbon. The color of the powders and hydrosols does not correlate with the content of non-diamond carbon. According to the EPR data, modified nanodiamonds possess a high level of diamond matrix shielding, and the extracted fractions differ in width of the basic transition area and in the SHF energy adsorption ratio. Due to this, F1 can be applied as precursors for CVD growth of nanocrystalline diamond and as field electron emission tips.

Держатели документа:
RAS, Inst Biophys SB, Krasnoyarsk 660036, Russia
ИБФ СО РАН : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Puzyr, A.P.; Bondar, V.S.; Bukayemsky, A.A.; Selyutin, G.E.; Kargin, V.F.; Gruen, DM \ed.\; Shenderova, OA \ed.\; She, erova, OA \ed.\

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9.


   
    Study of the luminescence system of the soil enchytraeid Fridericia heliota (Annelida: Clitellata: Oligochaeta: Enchytraeidae) / V. N. Petushkov, N. S. Rodionova, V. S. Bondar' // Doklady Biochemistry and Biophysics. - 2003. - Vol. 391, Is. 1-6. - P204-207, DOI 10.1023/A:1025105323648 . - ISSN 1607-6729
Кл.слова (ненормированные):
adsorption chromatography -- animal cell -- annelid worm -- article -- luminescence -- nonhuman -- purification -- animal -- drug antagonism -- isolation and purification -- metabolism -- physiology -- soil -- Animalia -- Annelida -- Clitellata -- Enchytraeidae -- edetic acid -- luciferase -- magnesium -- Animals -- Edetic Acid -- Luciferases -- Luminescent Measurements -- Magnesium -- Oligochaeta -- Soil

Scopus
Держатели документа:
Institute of Biophysics, Siberian Division, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk 660036, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Petushkov, V.N.; Rodionova, N.S.; Bondar', V.S.

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10.


   
    Effects of Nanodiamonds of Explosive Synthesis on the Skin of Experimental Animals Locally Exposed to Cobalt and Chrome Ions / V. I. Prokhorenkov [et al.] // Bull. Exp. Biol. Med. - 2014. - Vol. 158, Is. 2. - P264-267, DOI 10.1007/s10517-014-2737-0 . - ISSN 0007-4888
Кл.слова (ненормированные):
allergic contact dermatitis -- chrome -- cobalt -- ions of bivalent metals -- nanodiamonds -- chromium -- cobalt -- nanodiamond -- adsorption -- animal -- chemistry -- Dermatitis, Allergic Contact -- drug effects -- guinea pig -- nonparametric test -- skin -- Adsorption -- Animals -- Chromium -- Cobalt -- Dermatitis, Allergic Contact -- Guinea Pigs -- Nanodiamonds -- Skin -- Statistics, Nonparametric
Аннотация: Experiments in vivo demonstrated the protective effect of modified nanodiamonds on guinea pig skin after local exposure cobalt ions, but not chrome ions. The observed differences are determined by different adsorption of these ions by nanodiamonds: in vitro experiments showed that nanodiamonds adsorbed cobalt ions, but not chrome ions from water solutions. The perspectives of using modified nanodiamonds as a new adsorbent for prevention of allergic contact dermatitis induced by ions of bivalent metals are discussed. © 2014, Springer Science+Business Media New York.

Scopus
Держатели документа:
V. F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation, Krasnoyarsk, Russian Federation
Institute of Biophysics, Siberian Division of Russian Academy of Sciences, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Prokhorenkov, V. I.; Vasil’eva, E. Y.; Puzyr’, A. P.; Bondar’, V. S.

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11.


   
    Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds / A. V. Baron [et al.] // Doklad. Biochem. Biophys. - 2016. - Vol. 469, Is. 1. - P244-246, DOI 10.1134/S1607672916040037 . - ISSN 1607-6729
Аннотация: Adsorption of viral particles from the blood plasma of patients with viral hepatitis B and C on modified nanodiamonds (MNDs) was shown in the in vitro experiments. PCR method showed the treatment of plasma with MNDs leads to a decrease in the viral load by 2–3 orders of magnitude or more in both cases studied. These results make it possible to predict the applicability of MNDs for the development of new technologies of hemodialysis and plasmapheresis for binding and removal of viral particles from the blood of infected patients. © 2016, Pleiades Publishing, Ltd.

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Держатели документа:
Institute of Biophysics, Siberian Branch, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, Russian Federation
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, Russian Federation
Krasnoyarsk Regional Center for Prevention and Control of AIDS, ul. Karla Marksa 47, Krasnoyarsk, Russian Federation
Voino-Yasenetskii State Medical University, Ministry of Health of the Russian Federation, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Russian Federation
Krasnoyarsk Branch of Hematology Research Center, Ministry of Health of the Russian Federation, Krasnoyarsk, Russian Federation
Krasnoyarsk Research Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Baron, A. V.; Osipov, N. V.; Yashchenko, S. V.; Kokotukha, Y. A.; Baron, I. J.; Puzyr, A. P.; Olkhovskiy, I. A.; Bondar, V. S.

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12.


   
    On the applicability of nanodiamonds produced by detonation synthesis for phenol testing in aqueous media / N. O. Ronzhin, A. P. Puzyr, V. S. Bondar // Dokl. Chem. - 2017. - Vol. 475, Is. 1. - P155-158, DOI 10.1134/S0012500817070011 . - ISSN 0012-5008
Аннотация: It was found that the catalytic effect of modified nanodiamonds (MND) in the H2O2–4-aminoantipyrine–phenol oxidative azo coupling reaction is due to microimpurities of iron and copper ions on the surface of nanoparticles. The efficiency of MND as a catalyst is determined by the amount of surface impurities of these ions and can be doubled by their additional adsorption on nanoparticles. Using MND for phenol indication ensures a linear yield of the colored product of the azo coupling reaction over an analyte concentration range of 0.05–10 ?g/mL. The possibility of reusing MND for phenol testing in aqueous samples was demonstrated. © 2017, Pleiades Publishing, Ltd.

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Держатели документа:
Institute of Biophysics, Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Ronzhin, N. O.; Puzyr, A. P.; Bondar, V. S.

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13.


   
    Detonation Nanodiamonds as a New Tool for Phenol Detection in Aqueous Medium / N. Ronzhin, A. Puzyr, V. Bondar // J. Nanosci. Nanotechnol. - 2018. - Vol. 18, Is. 8. - P5448-5453, DOI 10.1166/jnn.2018.15382. - Cited References:27. - This work was supported by the state budget allocated to the fundamental research at the Russian Academy of Sciences (Project No. 0356-2016-0709) and Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research (Project No. 16-43-243027). . - ISSN 1533-4880. - ISSN 1533-4899
РУБ Chemistry, Multidisciplinary + Nanoscience & Nanotechnology + Materials
Рубрики:
ENVIRONMENTAL-POLLUTANTS
   DRUG-DELIVERY

   PARTICLES

   CARBON

Кл.слова (ненормированные):
Detonation Nanodiamonds -- Catalytic Activity -- Metal Ions -- Azo Coupling -- Reaction -- Phenol Detection
Аннотация: This paper demonstrates the effectiveness of using detonation nanodiamonds (DNDs) for detecting phenol in aqueous medium. The study has shown that the catalytic effect of DNDs in the oxidative azo coupling reaction (phenol-4-aminoantipyrine-hydrogen peroxide) is produced by trace amounts of iron and copper ions adsorbed on the surface of nanoparticles. The effectiveness of DNDs as a catalyst is determined by the amounts of these adsorbates and can be enhanced by a factor of two by additional adsorption of these ions onto the nanoparticles. A rise in the temperature of the ONO-catalyzed azo coupling reaction leads to a considerable (4.5-fold) increase in the reaction product yield. DNDs used to detect phenol in aqueous medium enable a linear increase in the yield of the product of the azo coupling reaction at concentrations of the analyte of between 0.05 and 10 mu g/mlThe study demonstrates that DNDs can be reused to detect phenol in water samples.

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Держатели документа:
RAS, SB, Krasnoyarsk Sci Ctr, Inst Biophys,Fed Res Ctr, Krasnoyarsk 660036, Russia.

Доп.точки доступа:
Ronzhin, Nikita; Puzyr, Alexey; Bondar, Vladimir; Russian Academy of Sciences [0356-2016-0709]; Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology [16-43-243027]

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14.


   
    Prolonged effects of nanodiamonds conjugated with corticosteroids / C. Kyu Rhee, A. E. Burov, A. P. Puzyr, V. S. Bondar // Appl Surf Sci. - 2021. - Vol. 551. - Ст. 149334, DOI 10.1016/j.apsusc.2021.149334 . - ISSN 0169-4332
Кл.слова (ненормированные):
Corticosteroids -- Delivery system -- Detonation nanodiamonds -- Modification -- Prolonged release -- Adsorption -- Controlled drug delivery -- Detonation -- Drug products -- Sodium compounds -- Suspensions (fluids) -- Targeted drug delivery -- Anti-inflammatory drugs -- Antineoplastic agents -- Aqueous suspensions -- Carrier for deliveries -- Detonation nanodiamonds -- Dexamethasone sodium phosphate -- Langmuir and freundlich adsorption -- Physical adsorption -- Nanodiamonds
Аннотация: The application of detonation nanodiamonds (DNDs) in delivery systems has been demonstrated many times for a variety of substances, including anti-inflammatory drugs, antibiotics, antineoplastic agents, vitamins etc. The applicability of detonation nanodiamonds as a carrier for delivery of corticosteroids is investigated in this study. Commercial DNDs were modified to obtain particles with high colloidal stability in aqueous suspensions. Physical adsorption was then used to conjugate the DNDs with methylprednisolone sodium succinate and dexamethasone sodium phosphate. The experimental adsorption isotherms were fit with Langmuir and Freundlich adsorption models. The results of in vitro release study demonstrated an explicit prolonged effect of DNDs, due to which a sustained release of the adsorbed drugs was provided. © 2021 Elsevier B.V.

Scopus
Держатели документа:
Korea Atomic Energy Research Institute, Daejeon, 34057, South Korea
Federal Research Center for Information and Computational Technologies, Krasnoyarsk, 660049, Russian Federation
Institute of Biophysics SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, Krasnoyarsk, 660036, Russian Federation

Доп.точки доступа:
Kyu Rhee, C.; Burov, A. E.; Puzyr, A. P.; Bondar, V. S.

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15.


   
    Prolonged effects of nanodiamonds conjugated with corticosteroids / C. K. Rhee, A. E. Burov, A. P. Puzyr, V. S. Bondar // Appl. Surf. Sci. - 2021. - Vol. 551: 16th International Symposium on Novel and Nano Materials (ISNNM) (NOV 03-06, 2020, Jeju, SOUTH KOREA). - Ст. 149334, DOI 10.1016/j.apsusc.2021.149334. - Cited References:26. - The authors are grateful to Daewha Alloytech Co., Ltd (Republic of Korea) for financial support of the research. . - ISSN 0169-4332. - ISSN 1873-5584
РУБ Chemistry, Physical + Materials Science, Coatings & Films + Physics,
Рубрики:
BIOMEDICAL APPLICATIONS
   SURFACE MODIFICATION

Кл.слова (ненормированные):
Detonation nanodiamonds -- Modification -- Corticosteroids -- Delivery system -- Prolonged release
Аннотация: The application of detonation nanodiamonds (DNDs) in delivery systems has been demonstrated many times for a variety of substances, including anti-inflammatory drugs, antibiotics, antineoplastic agents, vitamins etc. The applicability of detonation nanodiamonds as a carrier for delivery of corticosteroids is investigated in this study. Commercial DNDs were modified to obtain particles with high colloidal stability in aqueous suspensions. Physical adsorption was then used to conjugate the DNDs with methylprednisolone sodium succinate and dexamethasone sodium phosphate. The experimental adsorption isotherms were fit with Langmuir and Freundlich adsorption models. The results of in vitro release study demonstrated an explicit prolonged effect of DNDs, due to which a sustained release of the adsorbed drugs was provided.

WOS
Держатели документа:
Korea Atom Energy Res Inst, Daejeon 34057, South Korea.
Fed Res Ctr Informat & Computat Technol, Krasnoyarsk 660049, Russia.
Krasnoyarsk Sci Ctr SB RAS, Inst Biophys SB RAS, Fed Res Ctr, Krasnoyarsk 660036, Russia.

Доп.точки доступа:
Rhee, Chang Kyu; Burov, Andrey E.; Puzyr, Alexey P.; Bondar, Vladimir S.; Daewha Alloytech Co., Ltd (Republic of Korea)

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16.


   
    Reusable System for Phenol Detection in an Aqueous Medium Based on Nanodiamonds and Extracellular Oxidase from Basidiomycete Neonothopanus nambi / N. O. Ronzhin, O. A. Mogilnaya, E. D. Posokhina, V. S. Bondar // Dokl. Biochem. Biophys. - 2021. - Vol. 499, Is. 1. - P220-224, DOI 10.1134/S1607672921040141. - Cited References:15 . - ISSN 1607-6729. - ISSN 1608-3091
РУБ Biochemistry & Molecular Biology + Biophysics
Рубрики:
PEROXIDASES
   EXPRESSION

Кл.слова (ненормированные):
nanodiamond -- extracellular oxidase -- basidiomycete Neonothopanus nambi -- indication system -- phenol
Аннотация: A reusable system for phenol determination in an aqueous medium was obtained by adsorption of extracellular oxidase from fungus Neonothopanus nambi onto modified nanodiamonds (MND) synthesized by detonation. It was found that the enzyme strongly binds to MND and exhibits catalytic activity in the reaction of co-oxidation of phenol with 4-aminoantipyrine without the addition of hydrogen peroxide. In the presence of the MND-oxidase complex, a significantly (by an order of magnitude) higher yield of the reaction product is recorded as compared to the yield in the presence of a free enzyme; the mechanism of the revealed effect is discussed. Model experiments have demonstrated the multiple use of the MND-oxidase complex for testing phenol in aqueous samples. The immobilized enzyme exhibits functional activity during long-term (2 months) storage of the MND-oxidase complex at 4 degrees C. The data obtained create the prerequisites for using the created system in environmental monitoring of water pollution with phenol.

WOS
Держатели документа:
Russian Acad Sci, Siberian Branch, Krasnoyarsk Sci Ctr, Inst Biophys,Fed Res Ctr, Krasnoyarsk, Russia.

Доп.точки доступа:
Ronzhin, N. O.; Mogilnaya, O. A.; Posokhina, E. D.; Bondar, V. S.

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