Библиотека института биофизики СО РАН

Главная

Базы данных

Труды сотрудников ИБФ СО РАН - результаты поиска

Вид поиска

Каталог книг и продолжающихся изданий библиотеки Института биофизики СО РАН

Иностранные журналы библиотеки Института биофизики СО РАН

Отечественные журналы библиотеки Института биофизики СО РАН

Каталог диссертаций ИБФ СО РАН

Труды сотрудников ИБФ СО РАН

Область поиска

Формат представления найденных документов:
полный	информационный	краткий

Отсортировать найденные документы по:
автору	заглавию	году издания	типу документа

Поисковый запрос: (<.>K=burn<.>)

Общее количество найденных документов : 2
Показаны документы с 1 по 2

The Use of Polymeric Microcarriers Loaded with Anti-Inflammatory Substances in the Therapy of Experimental Skin Wounds / A. V. Murueva [et al.] // Bulletin of Experimental Biology and Medicine. - 2014, DOI 10.1007/s10517-014-2624-8 . - ISSN 0007-4888
Аннотация: We studied the effects of anti-inflammatory substances incorporated in polymeric microparticles made of degradable natural polyhydroxyalkanoate polyesters on experimental skin wounds caused by chemical burns in laboratory animals. Treatment with encapsulated forms of anti-inflammatory substances (applied in gel) accelerated wound healing in comparison with routine therapy (estimated by area of burn wound, wound healing activity, number of acanthotic cells, and number of hair and sebaceous follicles). The results showed the perspectives of usage of developed form of substances (degradable polymeric microparticles) for treatment of skin defects.

Scopus
Держатели документа:
Institute of Biophysics, Siberian Division of Russian Academy of SciencesKrasnoyarsk, Russian Federation
Institute of Fundamental Biology and Biotechnology of Siberian Federal UniversityKrasnoyarsk, Russian Federation : 660036, Красноярск, Академгородок, д. 50, стр. 50

Доп.точки доступа:
Murueva, A.V.; Shershneva, A.M.; Shishatskaya, E.I.; Volova, T.G.

Найти похожие

Biotechnological wound dressings based on bacterial cellulose and degradable copolymer P(3HB/4HB) / T. G. Volova [et al.] // Int. J. Biol. Macromol. - 2019. - Vol. 131. - P230-240, DOI 10.1016/j.ijbiomac.2019.03.068. - Cited By :1 . - ISSN 0141-8130
Кл.слова (ненормированные):
Bacterial cellulose -- Composites -- Polyhydroxyalkanoates -- 3 hydroxybutyric acid 4 hydroxybutyric acid copolymer -- actovegin -- bacterial cellulose -- cellulose -- collagen type 1 -- copolymer -- cytokeratin 10 -- cytokeratin 14 -- solcoseryl -- unclassified drug -- angiogenesis -- animal cell -- animal experiment -- animal model -- animal tissue -- biochemical analysis -- biocompatibility -- burn -- cell growth -- controlled study -- cutaneous parameters -- differential scanning calorimetry -- drug release -- elemental analysis -- female -- fibroblast -- histopathology -- in vitro study -- in vivo study -- inflammation -- mechanics -- nonhuman -- rat -- Review -- wound healing -- wound planimetry -- X ray analysis
Аннотация: Hybrid wound dressings have been constructed using two biomaterials: bacterial cellulose (BC) and copolymer of 3-hydroxybutyric and 4-hydroxybutyric acids [P(3HB/4HB)] – a biodegradable polymer of microbial origin. Some of the experimental membranes were loaded with drugs promoting wound healing and epidermal cells differentiated from multipotent adipose-derived mesenchymal stem cells. A study has been carried out to investigate the structure and physical/mechanical properties of the membranes. The in vitro study showed that the most effective scaffolds for growing fibroblasts were composite BC/P(3HB/4HB) films loaded with actovegin. Two types of the experimental biotechnological wound dressings – BC/P(3HB/4HB)/actovegin and BC/P(3HB/4HB)/fibroblasts – were tested in vivo, on laboratory animals with model third-degree skin burns. Wound planimetry, histological examination, and biochemical and molecular methods of detecting factors of angiogenesis, inflammation, type I collagen, and keratin 10 and 14 were used to monitor wound healing. Experimental wound dressings promoted healing more effectively than VoskoPran – a commercial wound dressing. © 2019

Scopus,
Смотреть статью,
WOS
Держатели документа:
Siberian Federal University, 79 Svobodnyi Av., Krasnoyarsk, 660041, Russian Federation
Institute of Biophysics of Siberian Branch of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, 660036, Russian Federation
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, 1 Partizan Zheleznyak Street, Krasnoyarsk, 660022, Russian Federation

Доп.точки доступа:
Volova, T. G.; Shumilova, A. A.; Nikolaeva, E. D.; Kirichenko, A. K.; Shishatskaya, E. I.

Найти похожие

Тематический навигатор

Другие библиотеки

Библиотека института физики

Центральная научная библиотека КНЦ СО РАН

Библиотека института химии и химический технологии

Библиотека института вычислительного моделирования

Библиотека института леса

Библиотека СФУ

Краевая научная библиотека

© Международная Ассоциация пользователей и разработчиков электронных библиотек и новых информационных технологий
(Ассоциация ЭБНИТ)