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1.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Kim P. D., Zamay S. S., Zamay T. N., Prokopenko V. S., Kolovskaya O. S., Zamay G. S., Princ, V. Ya., Seleznev V. A., Komonov A. I., Spivak E. A., Rudenko R. Y., Dubinina A. V., Komarov A. V., Denisenko V. V., Komarova M. A., Sokolov A. E., Narodov A. A., Zjivaev V. P., Zamay A. S.
Заглавие : The antitumor effect of magnetic nanodisks and DNA aptamer conjugates
Коллективы : Russian Science Foundation [14-15-00805]
Место публикации : Dokl. Biochem. Biophys.: MAIK Nauka-Interperiodica / Springer, 2016. - Vol. 466, Is. 1. - P.66-69. - ISSN 1607-6729, DOI 10.1134/S1607672916010154. - ISSN 1608-3091(eISSN)
Примечания : Cited References:7. - This work was supported by the Russian Science Foundation (project no. 14-15-00805).
Предметные рубрики: Nanoparticles
Cells
Аннотация: Here we describe a method of forming large arrays (up to 109 pieces) of free magnetic Ni-nanodisks 50 nm thick coated on both sides with layers of 5 nm thick Au. The antitumor effect of the magnetic nickel gold-coated nanodisks and DNA aptamer conjugates was evaluated in vivo and in vitro. Under the influence of rotating magnetic field, the studied nanodisks can cause the death of Ehrlich ascites carcinoma cells.
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2.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Gunyakov V. A., Krakhalev M. N., Zyryanov V. Ya., Shabanov V. F., Loiko V. A.
Заглавие : Modulation of defect modes intensity by controlled light scattering in photonic crystal with liquid crystal domain structure
Коллективы : Conference on Electromagnetic and Light Scattering
Место публикации : J. Quant. Spectrosc. Radiat. Transf. - 2016. - Vol. 178: Electromagnetic and light scattering by nonspherical particles XV: Celebrating 150 years of Maxwell's electromagnetics. - P.152-157. - ISSN 0022-4073, DOI 10.1016/j.jqsrt.2015.11.018. - ISSN 1879-1352(eISSN)
Примечания : Cited References:24
Предметные рубрики: Transmission
Cells
Ключевые слова (''Своб.индексиров.''): photonic crystal--liquid crystal--spatial extended system--electrohydrodynamic instability--light scattering
Аннотация: A method to modulate the defect modes intensity in a multilayer photonic crystal with a nematic liquid crystal layer arranged midmost has been proposed. The various electro-hydrodynamic domain structures (Williams domains, oblique rolls and grid pattern) were formed in the nematic layer under the action of ac electric field. The domains cause a polarization-sensitive light scattering which leads to an anisotropic reduction of the defect modes intensity. Thus by varying the applied voltage, we can tune gradually the transmittance spectrum of photonic crystal. In addition, the spectrum strongly depends on the light polarization direction above threshold voltage. (C) 2015 Elsevier Ltd. All rights reserved.
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3.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Shishatskaya E. I., Nikitovic D., Shabanov A. V., Tzanakakis G. N., Tsatsakis A. M., Menzianova N. G.
Заглавие : Short-term culture of monocytes as an in vitro evaluation system for bionanomaterials designated for medical use
Место публикации : Food Chem. Toxicol.: Elsevier, 2016. - Vol. 96. - P.302-308. - ISSN 02786915 (ISSN), DOI 10.1016/j.fct.2016.08.025
Примечания : Cited References: 46
Предметные рубрики: MAGNETIC NANOPARTICLES
CELLULAR REDUCTION
PROTEIN CORONA
CELLS
MECHANOTRANSDUCTION
NANOMATERIALS
LOCALIZATION
BIOMATERIALS
CYTOSKELETON
ACTIVATION
Ключевые слова (''Своб.индексиров.''): biocompatible biopolymers--polyhydroxyalkanoates--nanomaterials--nanodiamonds--fullerenes--bio-nanomaterials--monocytes
Аннотация: We studied the feasibility of using a short-term culture of monocytes, isolated from peripheral donor blood, to assess the biological activity of different types of bionanomaterials (BNM): biodegradable polimeric particles, fiber and film substrates of micro- and nano-dimensions, fullerenes (F) and nanodiamonds (ND), which are either currently in use and/or potentially applicable in medicine. Additionally, the effect of creating a protein corona on ND and F particles was investigated. The cellular reduction of (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) is a well-established tool for assessing the viability/metabolic activity of cells. The scanning electron microscopy assay can detect fine changes in cell morphology. In the present study BNM have been shown to affect; in a size, chemical composition and morphological characteristics-dependent manner, the ability of monocytes to reduce MTT as well as their morphology. Moreover, the specific effects of ND and F on MTT reduction and cell morphology were exhibited in a dose-dependent manner and sensitive to the formation of surface protein corona. Our results suggest that short-term culture of monocytes is a sensitive model system for assessing the biological effects of BMPs in vitro. © 2016 Elsevier Ltd
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