Библиотека института физики им. Л.В. Киренского СО РАН

Главная

Базы данных

Труды сотрудников ИФ СО РАН - результаты поиска

Вид поиска

Каталог книг и брошюр библиотеки ИФ СО РАН

Каталог журналов библиотеки ИФ СО РАН

Труды сотрудников ИФ СО РАН

Область поиска

Формат представления найденных документов:
полный	информационный	краткий

Отсортировать найденные документы по:
автору	заглавию	году издания	типу документа

Поисковый запрос: (<.>K=Antibiotics<.>)

Общее количество найденных документов : 6
Показаны документы с 1 по 6

A complex of ceftriaxone with Pb(II): synthesis, characterization, and antibacterial activity study / A. O. Lykhin [et al.] // J. Coord. Chem. - 2014. - Vol. 67, Is. 16. - З. 2783-2794, DOI 10.1080/00958972.2014.938065. - Cited References: 48. - The reported study was supported by RFBR, research project No. 14-03-31, 170 MOJI_a and Krasnoyarsk regional fund for supporting scientific and technological activities. We thank the Center for Equipment Joint Use of the Siberian Federal University. We are grateful to the HPC Research Departments of Siberian Federal University and Moscow University Supercomputing Center (SKIF MSU "Chebyshev") for the access to the high-performance computer clusters. . - ISSN 0095-8972. - ISSN 1029-0389

РУБ Chemistry, Inorganic & Nuclear
Рубрики:
BETA-LACTAM ANTIBIOTICS
   TERNARY COMPLEX
   METAL-COMPLEXES
   BASIS-SETS
   3 DECADES
   RESISTANCE
   COPPER(II)
   CEPHALOSPORINS
   EVOLUTION
   1ST-ROW
Кл.слова (ненормированные):
Ceftriaxone lead(II) complex -- DFT -- IR spectroscopy -- TGA -- Antibacterial screening
Аннотация: A Pb(II) complex with ceftriaxone (H2Ceftria) antibiotic was synthesized by reaction of ceftriaxone disodium salt (hemi)heptahydrate with lead nitrate in water–ethanol medium. The complex was characterized on the basis of complexometric titration, spectrophotometric and thermogravimetric analyses, capillary electrophoresis, IR, Raman and UV–vis spectroscopies, and density functional theory calculations. Pb(II) is five-coordinate with distorted square pyramidal geometry. The coordination of Ceftria2− to Pb(II) occurs through N and O of the triazine, lactam carbonyl, carboxylate, and amine groups. The antibacterial activity study showed that Klebsiella pneumoniae is resistant to [Pb(Ceftria)]·3H2O. The antibacterial activity of [Pb(Ceftria)]·3H2O against Staphylococcus aureus is reduced compared with ceftriaxone. In contrast, the antibacterial activity of [Pb(Ceftria)]·3H2O against Escherichia coli is 28% higher than that of ceftriaxone antibiotic.

Смотреть статью,
Scopus,
WOS,
Читать в сети ИФ
Держатели документа:
Siberian Fed Univ, Dept Chem, Krasnoyarsk, Russia
Siberian State Aerosp Univ, Informat Sci & Telecommun Inst, Krasnoyarsk, Russia
Russian Acad Sci, LV Kirensky Inst Phys, Siberian Branch, Krasnoyarsk, Russia
Siberian State Technol Univ, Dept Phys, Krasnoyarsk, Russia
Univ Nevada, Dept Chem, Reno, NV 89557 USA

Доп.точки доступа:
Lykhin, A. O.; Лыхин А. О.; Novikova, G. V.; Новикова Г. В.; Kuzubov, A. A.; Кузубов, Александр Александрович; Staloverova, N. A.; Сталоверова Н. А.; Sarmatova, N. I.; Сарматова Н. И.; Varganov, S. A.; Варганов, Сергей Александрович; Krasnov, P. O.; Краснов, Павел Олегович; RFBR [14-03-31, 170 MOJI_a]
}
Найти похожие

Golovnev, N. N.
Structure of two new compounds of fluoroquinolone antibiotics with mineral acids / N. N. Golovnev, A. D. Vasil’ev // Russ. J. Inorg. Chem. - 2016. - Vol. 61, Is. 11. - P. 1419-1422, DOI 10.1134/S0036023616110073. - Cited References: 19 . - ISSN 0036-0236
Кл.слова (ненормированные):
Single crystals -- X ray diffraction -- Crystallographic data -- Fluoroquinolone antibiotics -- Intra- and intermolecular hydrogen bonds -- Levofloxacin -- Mineral acid -- Pi interactions -- Space Groups -- Sparfloxacin -- Hydrogen bonds
Аннотация: New compounds of sparfloxacin (C19H22F2N4O3, SfH) and levofloxacin (C18H20FN3O4, LevoH) with mineral acids, namely, sparfloxacinium bromide (SfH · HBr, I) and levofloxacindium diperchlorate (LevoH · 2HClO4, II), have been synthesized and characterized by X-ray diffraction. Crystallographic data are a = 7.7151(7) Å, , b = 26.109(3) Å,с = 10.008(1) Å, β = 103.556(1)°, V = 1959.7(3) Å3, space group P21/n, Z = 4 for I and a = 9.727(6) Å, b = 20.440(12) Å, с = 12.286(7) Å, β = 104.327(8)°, V = 2367(2)Å3, space group P21, Z = 4 for II. The structures of these compounds are stabilized by intra- and intermolecular hydrogen bonds and π–π interaction between SfH2 + or LevoH3 2+ ions. © 2016, Pleiades Publishing, Ltd.

Смотреть статью,
Scopus,
WOS,
Читать в сети ИФ

Публикация на русском языке Головнев, Николай Николаевич. Структура двух новых соединений фторхинолоновых антибиотиков с минеральными кислотами [Текст] / Н. Н. Головнев, А. Д. Васильев // Журн. неорг. химии : Наука, 2016. - Т. 61 № 11. - С. 1472-1475

Держатели документа:
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, Russian Federation
Kirenskii Institute of Physics, Siberian Branch, Russian Academy of Sciences, Akademgorodok 50/38, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Vasil'ev, A. D.; Васильев, Александр Дмитриевич; Головнев, Николай Николаевич
}
Найти похожие

Antibacterial properties of films of cellulose composites with silver nanoparticles and antibiotics / T. G. Volova [et al.] // Polym Test. - 2018. - Vol. 65. - P. 54-68, DOI 10.1016/j.polymertesting.2017.10.023. - Cited References: 61. - The reported study was funded by Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research project № 16-43-242024 . The study was supported by the State budget allocated to the fundamental research at the Russian Academy of Sciences (project No AAAA-A17-117013050028-8 ). . - ISSN 0142-9418
Кл.слова (ненормированные):
Bacterial cellulose -- Composites -- Silver nanoparticles -- Antibiotics -- Properties -- Antibacterial activity
Аннотация: The present study describes production of bacterial cellulose composites with silver nanoparticles and antibiotics and compares their properties. Bacterial cellulose (BC) composites synthesized in the culture of the strain of acetic acid bacterium Komagataeibacter xylinus VKPM B-12068 with silver nanoparticles, BC/AgNps, were produced hydrothermally, under different AgNO3 concentrations (0.0001, 0.001, and 0.01 M) in the reaction medium. The presence of silver in the BC/AgNp composites was confirmed by elemental analysis conducted using scanning electron microscopy with a system of X-ray spectral analysis. Analysis showed that the average atomic number of silver particles in composite samples depended on the concentration of AgNO3: as AgNO3 concentration in the reaction solution was increased, silver content in the composites increased from 0.044 to 0.37 mg/cm2. BC composites with amikacin and ceftriaxone were prepared by immersing dry BC films in solutions containing different concentrations of the antibiotics. The surface structure and properties and physicochemical and mechanical characteristics of composites were investigated using SEM, DSC, X-ray analysis, the system for measuring water contact angles, and electromechanical tensile testing machine. The disk-diffusion method and the shake-flask culture method used in this study showed that all experimental composites had pronounced antibacterial activity against E. coli, Ps. eruginosa, K. pneumoniae, and St. aureus, and the BC/antibiotic composites were more active than BC/AgNp ones; S. aureus was the most susceptible to the effect of BC composites. No potential cytotoxicity was detected in any of the BC/AgNp composites in the NIH 3T3 mouse fibroblast cell culture, in contrast to the BC/antibiotic composites. These results suggest that BC composites constructed in the present study hold promise as dressings for managing wounds, including contaminated ones.

Смотреть статью,
Scopus,
WOS,
Читать в сети ИФ
Держатели документа:
Siberian Federal University, 79 Svobodnyi Av., Krasnoyarsk, Russian Federation
Institute of Biophysics SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, 50/50 Akademgorodok, Krasnoyarsk, Russian Federation
Kirensky Institute of Physics SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS”, 43/50 Akademgorodok, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Volova, T. G.; Shumilova, A. A.; Shidlovskiy, I. P.; Nikolaeva, E. D.; Sukovatiy, A. G.; Vasiliev, A. D.; Васильев, Александр Дмитриевич; Shishatskaya, E. I.
}
Найти похожие

    Способ адресной доставки антибиотика в полости носа при раневых и воспалительных процессах (экспериментальное исследование) / К. Г. Добрецов [и др.] // Рос. ринология. - 2017. - Т. 25, № 4. - С. 3-8, DOI 10.17116/rosrino20172543-8. - Библиогр.: 10 . - ISSN 0869-5474
   Перевод заглавия: The method of the targeted delivery of an antibiotic into the nasal cavity for the treatment of wounds and inflammatory processes (an experimental study)
Кл.слова (ненормированные):
магнитные наночастицы -- магнитное поле -- антибиотики -- рана -- воспаление -- раневой процесс -- местное лечение -- полость носа -- ринохирургия -- magnetic nanoparticles -- magnetic field -- antibiotics -- wounds -- inflammation -- wound process -- topical treatment -- nasal cavity -- rhinosurgery
Аннотация: Экспериментальные исследования были выполнены на 30 крысах. Порошок амоксиклава (амоксициллин с клавулановой кислотой) растворяли в золе магнитных наночастиц ферригидрита. Полученным раствором смачивали марлевую салфетку и прикладывали к ране, после чего воздействовали внешним магнитным полем. При этом наблюдались выраженное снижение микробной контаминации раны и более быстрая эпителизация. Бактериологический контроль ран подтвердил высокую антибактериальную активность комплекса наночастица—ампициллин в отношении микроорганизмов рода Staphylococcus и сохранения нормальной микрофлоры эпидермиса животных. Эти данные были также подтверждены гистологически. Положительные результаты экспериментальных исследований по проникающей способности магнитных наночастиц в ткани носа, а также эффективность адресной доставки антибиотика при раневом и воспалительном процессах свидетельствуют о целесообразности дальнейших исследований и практическом применении их результатов в ринохирургии.
These experimental studies were performed on 30 rats. The amoxiclav powder was dissolved in the ashes of magnetic ferrihydrite nanoparticles. The resulting solution was moistened with a gauze cloth and applied to the wounds after which an external magnetic field was applied to the animals. The targeted administration of the drug resulted in the well apparent reduction of the microbial contamination of the wounds and their accelerated epithelization in comparison with those in the control animals. The results of the bacteriological control confirmed the high antibacterial activity of the nanoparticle-ampicillin complex with respect to the microorganisms of the genus Staphylococcus, in the absence of its detrimental effect on the state of the normal microflora in the epidermis of the experimental animals. These observations were also verified in the histological studies. The positive results of the present experimental studies are in excellent agreement with the data obtained in the earlier investigations on the penetration and distribution of magnetic nanoparticles in the nasal tissues and give evidence of the high effectiveness of the targeted delivery of antibiotics into the nasal cavity for the treatment of wounds and inflammatory processes. Moreover, they provide a basis for the further research and subsequent practical application of this method in rhinosurgery.

Смотреть статью,
РИНЦ,
Читать в сети ИФ
Держатели документа:
Институт физики им. Л.В. Киренского Сибирского отделения РАН
Научно-исследовательский институт медицинских проблем Севера
ФГАОУ ВО «Сибирский федеральный университет»
ФГБНУ «Федеральный исследовательский центр Красноярский научный центр» Сибирского отделения РАН
ФГБУ «Федеральный Сибирский научно-клинический центр» Федерального медико-биологического агентства

Доп.точки доступа:
Добрецов, К. Г.; Dobretsov K. G.; Столяр, Сергей Викторович; Stolyar, S. V.; Коленчукова, О. А.; Kolenchukova O. A.; Чижова, И. А.; Chizhova I. A.; Инжеваткин, Е. В.; Inzhevatkin E. V.
}
Найти похожие

    Phytogenic Synthesis of Ag Bionano-Antibiotics Against ESKAPE Drug Resistant Communities in Krasnoyarsk, Siberia / B. Syed [et al.] // J. Cluster Sci. - 2019. - Vol. 30, Is. 3. - P. 589-597, DOI 10.1007/s10876-019-01518-7. - Cited References: 44. - uthors are thankful for facilities provided by Siberian Federal University to carry out the present study. Authors are grateful to Krasnoyarsk Medical University for providing opportunity to carry out the present study. . - ISSN 1040-7278
   Перевод заглавия: Фитогенный синтез биологических нано-антибиотиков на основе серебра против фармакорезистентных болезнетворных микроорганизмов, распространенных в Красноярске, Россия
Кл.слова (ненормированные):
Heracleum dissectum -- Silver nano-antibiotics -- ESKAPE -- Antimicrobial-resistant -- Krasnoyarsk -- Siberia
Аннотация: The present study reports synthesis of silver nano-antibiotics from aqueous extract of H. dissectum. The nano-antibiotics were characterized using UV–visible spectra which displayed maximum absorbance at 430 nm. The role of phytocomponents as reducing agent and stabilization of silver nano-antibiotics was depicted with Fourier-transform infrared spectroscopy which revealed presence of hydroxyl and carboxyl groups associated with silver nano-antibiotics. The crystalline nature was studied with X-ray diffraction which showed Bragg’s intensities at 2θ angle which denoted (101), (111), (200), (220), (311) planes. The morphological characteristics were studied using Transmission Electron Microscopy to reveal the size ranging from 5 to 50 nm. The bactericidal activity of nano-antibiotics was studied via well diffusion and minimal inhibitory concentration assay against members of drug-resistant communities bearing resistant to more than ten standard antibiotics. Nano-antibiotics displayed highest activity against Ps. aeruginosa strain 55 and Methicillin-resistant Staphylococcus aureus with 16 mm zone of inhibition followed by Kl. pneumoniae strain 104 and E. coli strain 55. Moderate activity was observed against Ac. baumannii strains with 12 mm zone of inhibition. The obtained results envision the role of plant mediated nano-antibiotics as one of the best suited alternatives towards combating drug resistant pathogens.

Смотреть статью,
Scopus,
WOS,
Читать в сети ИФ
Держатели документа:
Department of Microbiology, Krasnoyasrk State Medical University named after Prof. VF. Voino-Yasenetskiy, Partizana-Zheleznyaka Street, 1, Krasnoyarsk, 660022, Russian Federation
Siberian Federal University, Svobodnyy pr., 79, Krasnoyarsk, 660041, Russian Federation
School of Fundamental Biology and Biotechnology, Siberian Federal University, Krasnoyarsk, Russian Federation
Federal Research Center KSC SB RAS, Kirensky Institute of Physics, Akademgorodok 50, Bld. 38, Krasnoyarsk, 660036, Russian Federation
School of Petroleum and Natural Gas Engineering, Siberian Federal University, Krasnoyarsk, Russian Federation
Department of Environmental Sciences, Jozef Stefan Institute, Jamova 39, Ljubljana, 1000, Slovenia
Department of Biotechnology, M. M. Engineering College, Maharishi Markandeshwar University (MMU), Mullana, Ambala, India

Доп.точки доступа:
Syed, B.; Prudnikova, S. V.; Perianova, O. V.; Zharkov, S. M.; Жарков, Сергей Михайлович; Kuzmin, A.; Chouhan, R. S.; Potkina, N. K.; Khohlova, O. Y.; Lobova, T. I.; Singh, M.
}
Найти похожие

Synthesis and synergistic effect of antibacterial composites based on concentrated hydrosols of silver nanoparticles combined with cephalosporins antibiotics / S. A. Vorobyev, G. V. Novikova, A. V. Demina [et al.] // Inorg. Chem. Commun. - 2022. - Vol. 144. - Ст. 109862, DOI 10.1016/j.inoche.2022.109862. - Cited References: 49. - This research was supported by the Russian Science Foundation, project 18-73-00142 . - ISSN 1387-7003
Кл.слова (ненормированные):
Silver nanoparticles -- Concentrated hydrosols -- Cephalosporin antibiotics -- Antibacterial activity -- Minimal inhibitory concentration
Аннотация: Silver nanoparticles may be used as potential antimicrobial agents. Concentrated silver nanoparticles (AgNPs) were synthesised by the Carey Lee method. Then, antibiotics, such as disodium ceftriaxone, sodium cefotaxime, sodium cefazolin and sodium cefoperazone, were added to the AgNPs at the ratio of AgNPs:antibiotic = 5:1. The concentrated hydrosols were examined using UV–Vis, FTIR-spectroscopy, dynamic light scattering and transmission electron microscopy. The spectra plasmon resonance of silver nanoparticles and their combination with antibiotics had a single strong peak at 412–415 nm. The transmission electron microscopy micrographs showed different forms. The average size of AgNPs-antibiotic particles was smaller than that of AgNPs. The antibacterial activities of AgNPs, antibiotics and AgNPs-antibiotics were determined by the disk diffusion method against Staphylococcus aureus and Escherichia coli. The most significant enhancement of the antibacterial effect over the antibiotic was demonstrated by AgNPs-disodium ceftriaxone against E.coli. Also, the minimal inhibitory concentration (MIC) of the AgNPs-antibiotics was defined. All the AgNPs-antibiotic exhibited a synergistic enhancement by AgNPs and the antibiotic of antibacterial activity. A possible explanation of this phenomenon was proposed. Our results suggest that the synthesis of the concentrated hydrosol of the AgNPs-antibiotics is essential for studying similar nanosystems.

Смотреть статью,
Scopus
Держатели документа:
Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of sciences, Krasnoyarsk, 660036, Russian Federation
School of Non-Ferrous Metals and Material Science, Siberian Federal University, Krasnoyarsk, 660041, Russian Federation
School of Fundamental Biology and Biotechnology, Siberian Federal University, Krasnoyarsk, 660041, Russian Federation
Kirensky Institute of Physics, Federal Research Center KSC Siberian Branch of Russian Academy of Sciences, Krasnoyarsk, 660036, Russian Federation
Reshetnev Siberian State University of Science and Technology, Krasnoyarsk, 660037, Russian Federation

Доп.точки доступа:
Vorobyev, S. A.; Novikova, G. V.; Demina, A. V.; Shidlovskiy, I. P.; Volochaev, M. N.; Волочаев, Михаил Николаевич
}
Найти похожие