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Каталог книг и брошюр библиотеки ИФ СО РАН

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Труды сотрудников ИФ СО РАН

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Electrospinning of polyhydroxyalkanoate fibrous scaffolds: effects on electrospinning parameters on structure and properties / T. . Volova [et al.] // J. Biomater. Sci.-Polym. Ed. - 2014. - Vol. 25, Is. 4. - P. 370-393, DOI 10.1080/09205063.2013.862400. - Cited References: 52. - This study was financially supported by Project 'Biotechnologies of novel biomaterials: innovative biopolymers and devices for biomedicine' (Agreement No. 1 of 15.02.2013 to Agreement No. 11.G34.31.0013) in accordance with Resolution No. 220 of the Government of the Russian Federation of April 9, 2010, 'On measures designed to attract leading scientists to the Russian institutions of higher learning' and Grant of the RF President for supporting young Doctors of Sciences No. MD-3112.2012.4. . - ISSN 0920-5063. - ISSN 1568-5624

РУБ Engineering, Biomedical + Materials Science, Biomaterials + Polymer Science
Рубрики:
TISSUE ENGINEERING APPLICATIONS
   FIBER MATS
   POLY 3-HYDROXYBUTYRATE
   POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYVALERATE)
   BIOCOMPATIBILITY
   PROLIFERATION
   FABRICATION
   NANOFIBERS
   COPOLYMERS
   MEMBRANES
Кл.слова (ненормированные):
electrospinning -- polyhydroxyalkanoates -- ultrafine fibers -- physical-mechanical properties -- fibroblast cells
Аннотация: IIn this study, electrospinning was used to prepare ultrafine fibers from PHAs with different chemical compositions: P(3HB) and copolymers: P(3HB-co-4HB), P(3HB-co-3HV), and P(3HB-co-3HHx). The main process parameters that influence ultrafine fiber diameter and properties (polymer concentration, solution feeding rate, working distance, and applied voltage) have been investigated and their effects evaluated. The study revealed electrospinning parameters for the production of high-quality ultrafine fibers and determined which parameters should be varied to tailor the properties of the products. This study is the first to compare biological and physical-mechanical parameters of PHAs with different chemical compositions as dependent upon the fractions of monomers constituting the polymers and ultrafine fiber orientation. Mechanical strength of aligned ultrafine fibers prepared from different PHAs is higher than that of randomly oriented ones; no significant effect of ultrafine fiber orientation on surface properties has been found. None of the fibrous scaffolds produced by electrospinning from PHAs had any adverse effects on attachment, growth, and viability of NIH 3T3 mouse fibroblast cells, and all of them were found to be suitable for tissue engineering applications.

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Держатели документа:
Russian Acad Sci, Inst Biophys, Siberian Branch, Krasnoyarsk 660036, Russia
Siberian Fed Univ, Inst Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia
Russian Acad Sci, LV Kirenskii Inst Phys, Siberian Branch, Krasnoyarsk 660036, RussiaИФ СО РАН;

Доп.точки доступа:
Volova, T.; Волова, Татьяна Григорьевна; Goncharov, D.; Sukovatyi, A. G.; Суковатый, Алексей Григорьевич; Shabanov, A. V.; Шабанов, Александр Васильевич; Nikolaeva, E.; Shishatskaya, E.; Project 'Biotechnologies of novel biomaterials: innovative biopolymers and devices for biomedicine' [1, 11.G34.31.0013]; Government of the Russian Federation [220]; RF President for supporting young Doctors of Sciences [MD-3112.2012.4]
}
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Properties of a novel quaterpolymer P(3HB/4HB/3HV/3HHx) / T. G. Volova [et al.] // Polymer. - 2016. - Vol. 101. - P. 67-74, DOI 10.1016/j.polymer.2016.08.048 . - ISSN 0032-3861
Кл.слова (ненормированные):
Physicochemical and mechanical properties -- Polyhydroxyalkanoates -- Quaterpolymers -- Biocompatibility -- Cell culture -- Chain length -- Chains -- Decomposition -- 3-Hydroxyhexanoate -- Degrees of crystallinity -- Elongation at break -- Physico-chemical and mechanical properties -- Polyhydroxyalkanoates -- Quaterpolymers -- Short chain lengths -- Thermal decomposition temperature -- Film preparation
Аннотация: Cupriavidus eutrophus В10646 was used to synthesize a series of polyhydroxyalkanoate (PHA) quaterpolymers composed of the short-chain-length 3-hydroxybutyrate (3HB), 4-hydroxybutyrate (4HB), and 3-hydroxyvalerate (3HV) and the medium-chain-length 3-hydroxyhexanoate (3HHx). The molar fraction of 3HB in the quaterpolymers varied between 63.5 and 93.1 mol.%, 3HV – between 1.1 and 24.6 mol.%, 4HB – between 2.4 and 15.6 mol.%, and 3HHx – between 0.4 and 4.8 mol.%. The properties of PHA quaterpolymers were significantly different from those of the P(3HB) homopolymer: they had much lower degrees of crystallinity (up to 30–45%), and lower melting points and thermal decomposition temperatures, with the interval between these temperatures remaining practically unchanged. Films prepared from PHA quaterpolymers were rougher and more porous than P(3HB) films; they showed higher values of elongation at break (up to 6–113%), i.e. were more elastic. Films prepared from PHA quaterpolymers were biocompatible and had no toxic effect on mouse fibroblast NIH 3T3 cells. © 2016 Elsevier Ltd

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Держатели документа:
Siberian Federal University, 79 Svobodnyi Avenue, Krasnoyarsk, Russian Federation
Institute of Biophysics of Siberian Branch of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, Russian Federation
Institute of Chemistry and Chemical Technology of Siberian Branch of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, Russian Federation
L.V. Kirensky Institute of Physics of Siberian Branch of Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, Russian Federation

Доп.точки доступа:
Volova, T. G.; Волова, Татьяна Григорьевна; Vinogradova, O. N.; Zhila, N. O.; Жила, Наталья Олеговна; Peterson, I. V.; Петерсон, Иван Викторович; Kiselev, E. G.; Киселев, Евгений Геннадьевич; Vasiliev, A. D.; Васильев, Александр Дмитриевич; Sukovatiy, A. G.; Суковатый, Алексей Григорьевич; Shishatskaya, E. I.; Шишацкая, Екатерина Игоревна
}
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Magnetic nanoparticles as a strong contributor to the biocompatibility of ferrogels / F. A. Blyakhman, E. B. Makarova, P. A. Shabadrov [et al.] // Phys. Metals Metallogr. - 2020. - Vol. 121, Is. 4. - P. 299-304, DOI 10.1134/S0031918X2004002X. - Cited References: 17. - This study was supported by the Russian Science Foundation, grant no. 18-19-00090. . - ISSN 0031-918X. - ISSN 1555-6190

РУБ Metallurgy & Metallurgical Engineering
Рубрики:
STIFFNESS
Кл.слова (ненормированные):
magnetic nanoparticles -- ferrogels -- cells -- tissue engineering
Аннотация: Biomedical engineering is the most promising field for the application of ferrogels as scaffolds for cell culturing in regenerative medicine, targeted drug delivery, and biosensorics. This study is focused on the contribution of ferric-oxide magnetic nanoparticles (MNPs) to the biocompatibility of ferrogels with human dermal fibroblasts. The results of experiments with polyacrylamide gels filled with MNPs are presented. These experiments demonstrate that, regardless of the mechanical and electrical characteristics of ferrogels, MNPs have a significant effect on the biological activity of cells.

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Публикация на русском языке Магнитные наночастицы как фактор, определяющий биосовместимость феррогелей [Текст] / Ф. А. Бляхман, Э. Б. Макарова, П. А. Шабадров [и др.] // Физ. металлов и металловед. - 2020. - Т. 121 № 4. - С. 339-345

Держатели документа:
Ural State Med Univ, Ekaterinburg 620028, Russia.
Ural Fed Univ, Ekaterinburg 620002, Russia.
Inst Med Cell Technol, Ekaterinburg 620026, Russia.
Russian Acad Sci, Kirensky Inst Phys, Siberian Branch, Fed Res Ctr,Krasnoyarsk Sci Ctr, Krasnoyarsk 660036, Russia.

Доп.точки доступа:
Blyakhman, F. A.; Makarova, E. B.; Shabadrov, P. A.; Fadeyev, F. A.; Shklyar, T. F.; Safronov, A. P.; Komogortsev, S. V.; Комогорцев, Сергей Викторович; Kurlyandskaya, G., V; Russian Science FoundationRussian Science Foundation (RSF) [18-19-00090]
}
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    Chemical modification of films from biosynthetic poly-3-hydroxybutyrate aimed to improvement of their surface properties / A. N. Boyandin, A. A. Sukhanova, E. D. Nikolaeva, I. V. Nemtsev // Macromolecular Symposia. - 2021. - Vol. 395: 4th International Conference on Progress on Polymers and Composites (NOV 26-28, 2020, Electr. Network), Is. 1. - Ст. 2000281, DOI 10.1002/masy.202000281. - Cited References: 11. - This work was carried out by the team of the scientific laboratory "Smart Materials and Structures" within the state assignment of the Ministry of Science and Higher Education of the Russian Federation for the implementation of the project "Development of multifunctional smart materials and structures based on modified polymer composite materials capable to function in extreme conditions" (No. FEFE-2020-0015). The surface of the samples was investigated using a scanning electron microscope Hitachi TM3000 in the Krasnoyarsk Regional Center of Research Equipment of Federal Research Center "Krasnoyarsk Science Center SB RAS" . - ISSN 1022-1360. - ISSN 1521-3900
   Перевод заглавия: Химическая модификация плёнок из биосинтетического поли-3-гидроксибутирата, направленная на улучшение их поверхностных свойств

РУБ Polymer Science

Кл.слова (ненормированные):
biocompatibility -- polyhydroxyalkanoates -- polyhydroxybutyrate -- polymer modification
Аннотация: Films from biodegradable poly-3-hydroxybutyrate are treated with chemical reagents to improve their hydrophilicity and biocompatibility. Two approaches are tested: a single treatment with alkali, acids, oxidizing or reducing agents, and a step-by step treatment of the alkali pre-activated surface of polymer films with bromine water and amino-compounds (ammonia or triethylamine). The maximal level of hydrophilicity (the lowest water contact angle and the highest polar component of the surface free energy) is registered after a single treatment with NaOH and after the step-by-step treatment. These samples also showed the best adhesion of mouse fibroblasts of NIH 3T3 line on the film surface. So, the proposed methods can be used to enhance hydropilicity and biocompatibility of biopolymer surface.

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Держатели документа:
Reshetnev Siberian State Univ Sci & Technol, 31 Krasnoyarsky Rabochy Av, Krasnoyarsk 660037, Russia.
Russian Acad Sci, Siberian Branch, Fed Res Ctr, Inst Biophys,Krasnoyarsk Sci Ctr, 50,Build 50, Krasnoyarsk 660036, Russia.
Russian Acad Sci, Siberian Branch, Int Sci Ctr Studying Extreme States Organism, Fed Res Ctr,Krasnoyarsk Sci Ctr, 50,Build 12-2, Krasnoyarsk 660036, Russia.
Russian Acad Sci, Siberian Branch, Krasnoyarsk Sci Ctr, Fed Res Ctr, 50 Akademgorodok, Krasnoyarsk 660036, Russia.

Доп.точки доступа:
Boyandin, A. N.; Sukhanova, Anna Alekseevna; Nikolaeva, Elena Dmitrievna; Nemtsev, I. V.; Немцев, Иван Васильевич; Ministry of Science and Higher Education of the Russian Federation [FEFE-2020-0015]; International Conference on Progress on Polymers and Composites(4th ; 26-28 Nov. 2020)
}
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Combined porous-monolithic TiNi materials surface-modified with electron beam for new-generation rib endoprostheses / A. V. Shabalina, S. G. Anikeev, S. A. Kulinich [et al.] // J. Funct. Biomater. - 2023. - Vol. 14, Is. 5. - Ст. 277, DOI 10.3390/jfb14050277. - Cited References: 57. - The study was supported by the Russian Science Foundation (grant no. 19-79-10045). https://rscf.ru/project/19-79-10045/ . - ISSN 2079-4983
Кл.слова (ненормированные):
TiNi -- rib endoprostheses -- porous coating -- powder metallurgy -- high-current pulsed electron beam -- structure -- surface modification -- electrochemical corrosion -- biocompatibility
Аннотация: TiNi alloys are very widely used materials in implant fabrication. When applied in rib replacement, they are required to be manufactured as combined porous-monolithic structures, ideally with a thin, porous part well-adhered to its monolithic substrate. Additionally, good biocompatibility, high corrosion resistance and mechanical durability are also highly demanded. So far, all these parameters have not been achieved in one material, which is why an active search in the field is still underway. In the present study, we prepared new porous-monolithic TiNi materials by sintering a TiNi powder (0–100 μm) on monolithic TiNi plates, followed by surface modification with a high-current pulsed electron beam. The obtained materials were evaluated by a set of surface and phase analysis methods, after which their corrosion resistance and biocompatibility (hemolysis, cytotoxicity, and cell viability) were evaluated. Finally, cell growth tests were conducted. In comparison with flat TiNi monoliths, the newly developed materials were found to have better corrosion resistance, also demonstrating good biocompatibility and potential for cell growth on their surface. Thus, the newly developed porous-on-monolith TiNi materials with different surface porosity and morphology showed promise as potential new-generation implants for use in rib endoprostheses.

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Держатели документа:
Laboratory of Medical Materials Science, Tomsk State University, 634050 Tomsk, Russia
Institute of Physics, Kazan Federal University, 420008 Kazan, Russia
Research Institute of Science and Technology, Tokai University, Hiratsuka 259-1292, Kanagawa, Japan
Research School of High-Energy Physics, National Research Tomsk Polytechnic University, 634050 Tomsk, Russia
Tomsk Scientific Center, Siberian Branch of Russian Academy of Sciences, 634055 Tomsk, Russia
Kirensky Institute of Physics, Federal Research Center, KSC Siberian Branch Russian Academy of Science, 660036 Krasnoyarsk, Russia
School of Engineering Physics and Radio Electronics, Siberian Federal University, 660041 Krasnoyarsk, Russia
Department of Morphology and Physiology of the Medical Institute, Surgut State University, 628403 Surgut, Russia

Доп.точки доступа:
Shabalina, A. V.; Anikeev, S. G.; Kulinich, S. A.; Artyukhova, N. V.; Vlasov, V. A.; Kaftaranova, M. I.; Hodorenko, V. N.; Yakovlev, E. V.; Pesterev, E. A.; Lukyanenko, A. V.; Лукьяненко, Анна Витальевна; Volochaev, M. N.; Волочаев, Михаил Николаевич; Pakholkina, S.; Mamazakirov, O.; Stolyarov, V. V.; Mokshin, A. V.; Gunther, V. E.
}
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