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Ferrihydrite nanoparticles interaction with model lipid membranes. / C. G. Chilom [et al.] // Chem. Phys. Lipids. - 2020. - Vol. 226. - Ст. 104851, DOI 10.1016/j.chemphyslip.2019.104851. - Cited References: 70. - The work was accomplished with the financial support of the 2019 RO-JINR Project Investigation of biogenic and chemically synthesized systems in interaction with biostructures for applied research, Theme 02-1-1107-2011/2019 and of the Romanian National Authority for Scientific Research, CNDI-UEFISCDI, Project numbers: PN 18 09 02 02/2018 and PN 19 06 02 03/2019. The authors are very much indebted to Professor Dr. Aurel Popescu, for very helpful suggestions and permanent encouragement. . - ISSN 0009-3084. - ISSN 1873-2941
Кл.слова (ненормированные):
Ferrihydrite nanoparticles -- Morphology -- Laurdan -- TMA-DPH -- Membrane -- Fluidity
Аннотация: In recent years was observed an increased interest towards the use of metal nanoparticles for various biomedical applications, such as therapeutics, delivery systems or imaging. As biological membranes are the first structures with which the nanoparticles interact, it is necessary to understand better the mechanisms governing these interactions. In the present paper we aim to characterize the effect of three different ferrihydrite nanoparticles (simple or doped with cooper or cobalt) on the fluidity of model lipid membranes. First we evaluated the physicochemical properties of the nanoparticles: size and composition. Secondly, their effect on lipid membranes was also evaluated using Laurdan, TMA-DPH and DPH fluorescence. Our results can help better understand the mechanisms involved in nanoparticles and membrane interactions.

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Держатели документа:
Department of Electricity, Solid State and Biophysics, Faculty of Physics, University of Bucharest, Magurele, Romania
Department of Life and Environmental Physics, "Horia Hulubei" National Institute of Physics and Nuclear Engineering, Magurele, Romania
Department of Nuclear Physics, "Horia Hulubei" National Institute of Physics and Nuclear Engineering, Magurele, Romania
Joint Institute for Nuclear Research, Dubna, Russia
Moscow Institute of Physics and Technology, Dolgoprudniy, Russia
Siberian Federal University, Krasnoyarsk, Russia
Kirensky Institute of Physics, SB RAS, Krasnoyarsk, 660036, Russia

Доп.точки доступа:
Chilom, Claudia G.; Zorilă, Bogdan; Bacalum, M.; Bălăşoiu, Maria; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Stolyar, S. V.; Столяр, Сергей Викторович; Tyutyunnicov, Sergey
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