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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Starkov A. K., Zamay T. N., Savchenko A. A., Ingevatkin E. V., Titova N. M., Kolovskaya O. S., Luzan N. A., Silkin P. P., Kuznetsova S. A.
Заглавие : Antitumor effect of arabinogalactan and platinum complex
Место публикации : Dokl. Biochem. Biophys.: MAIK Nauka-Interperiodica / Springer, 2016. - Vol. 467, Is. 1. - P.92-94. - ISSN 16076729 (ISSN), DOI 10.1134/S1607672916020046
Примечания : Cited References: 7. - This study was supported by the Ministry of Education and Science of the Russian Federation (agreement no. 14.607.21.0104). This study was performed using the shared-access equipment center of the Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences.
Аннотация: The article presents the results of investigation of antitumor properties of platinum–arabinogalactan complex. We showed the ability of the complex to inhibit the growth of Ehrlich ascites tumor cells. It is found that the distribution of the platinum–arabinogalactan complex is not specific only for tumor cells in mice. The complex was found in all tissues and organs examined (ascites cells, embryonic cells, kidney, and liver). The mechanism of action of the arabinogalactan–platinum complex may be similar to cisplatin as the complex is able to accumulate in tumor cells. © 2016, Pleiades Publishing, Ltd.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Kolovskaya O. S., Zamay T. N., Zamay G. S., Babkin V. A., Medvedeva E. N., Neverova N. A., Kirichenko A. K., Zamay S. S., Lapin I. N., Morozov E. V., Sokolov A. Е., Narodov A. A., Fedorov D. G., Tomilin F. N., Zabluda V. N., Alekhina Yu., Lukyanenko K. A., Glazyrin Yu. E., Svetlichnyi V. A., Berezovski M. V., Kichkailo A. S.
Заглавие : Aptamer-conjugated superparamagnetic ferroarabinogalactan nanoparticles for targeted magnetodynamic therapy of cancer
Место публикации : Cancers. - 2020. - Vol. 12, Is. 1. - Ст.216. - ISSN 2072-6694 (eISSN), DOI 10.3390/cancers12010216
Примечания : Cited References: 46. - This research was funded by the Ministry of Science and Higher Education of the Russian Federation; project 0287-2019-0007
Аннотация: Nanotechnologies involving physical methods of tumor destruction using functional oligonucleotides are promising for targeted cancer therapy. Our study presents magnetodynamic therapy for selective elimination of tumor cells in vivo using DNA aptamer-functionalized magnetic nanoparticles exposed to a low frequency alternating magnetic field. We developed an enhanced targeting approach of cancer cells with aptamers and arabinogalactan. Aptamers to fibronectin (AS-14) and heat shock cognate 71 kDa protein (AS-42) facilitated the delivery of the nanoparticles to Ehrlich carcinoma cells, and arabinogalactan (AG) promoted internalization through asialoglycoprotein receptors. Specific delivery of the aptamer-modified FeAG nanoparticles to the tumor site was confirmed by magnetic resonance imaging (MRI). After the following treatment with a low frequency alternating magnetic field, AS-FeAG caused cancer cell death in vitro and tumor reduction in vivo. Histological analyses showed mechanical disruption of tumor tissues, total necrosis, cell lysis, and disruption of the extracellular matrix. The enhanced targeted magnetic theranostics with the aptamer conjugated superparamagnetic ferroarabinogalactans opens up a new venue for making biocompatible contrasting agents for MRI imaging and performing non-invasive anti-cancer therapies with a deep penetrated magnetic field.
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Stolyar S. V., Yaroslavtsev R. N., Chekanova L. A., Komogortsev S. V., Cheremiskina E. V., Neznakhin D. S., Iskhakov R. S.
Заглавие : CoC films sinthezited whis arabinogalactan
Коллективы : Nanostructures: Physics and Technology, International Symposium, Институт физики им. Б. И. Степанова НАН Беларуси, Санкт-Петербургский национальный исследовательский Академический университет Российской академии наук, Физико-технический институт им. А.Ф. Иоффе РАН, Научно-технологический центр микроэлектроники и субмикронных гетероструктур Российской академии наук
Место публикации : Nanostructures: Physics and Technology, International Symposium (28 ; 2020 ; 28 Sept.-2 Oct. ; Minsk, Belarus). Nanostructures: physics and technology: proc. 28th Int. symp. - 2020. - Ст.NT.19. - P.105-106. - ISBN 978-5-93634-066-6
Примечания : Cited References: 1
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Shadrin K. V., Yakovleva Yu. A., Kryukova O. V., Makarskaya G. V., Tarskikh S. V., Pyankov V. F., Pakhomova V. G., Gerasimova Yu. V., Yaroslavtsev R. N., Vorobyev S. A., Stolyar S. V.
Заглавие : Influence of arabinogalactan-coated selenium nanoparticles on the formation of free radicals in Ehrlich ascites carcinoma cells
Колич.характеристики :8 с
Место публикации : BioNanoScience. - 2024. - Vol. 14, Is. 1. - P.268-275. - ISSN 21911630 (ISSN), DOI 10.1007/s12668-023-01251-6. - ISSN 21911649 (eISSN)
Примечания : Cited References: 40
Аннотация: The antioxidant properties of selenium nanoparticles coated with arabinogalactan have been studied. The nanoparticles were characterized by transmission electron microscopy and infrared spectroscopy. Arabinogalactan-coated selenium nanoparticles were incubated together with Ehrlich ascitic carcinoma cells and then exposed to microwave radiation. The antioxidant properties of selenium nanoparticles were evaluated using chemiluminescent analysis. The viability of Ehrlich ascitic carcinoma cells under microwave irradiation and incubation with selenium nanoparticles was assessed by flow cytometry. Under conditions of exposure to experimental tumor cells of microwave radiation, the concentration of free radicals in the cells did not change. The effect of arabinogalactan-coated selenium nanoparticles on tumor cells is expressed as an increase in the delay time for the activation of the antioxidant system.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Stolyar S. V., Kryukova O. V., Yaroslavtsev R. N., Bayukov O. A., Knyazev Yu. V., Gerasimova Yu. V., Pyankov V. F., Latyshev N. V., Shestakov N. P.
Заглавие : Influence of magnetic nanoparticles on cells of Ehrlich ascites carcinoma
Место публикации : AIP Adv. - 2021. - Vol. 11, Is. 1. - Ст.015019. - ISSN 21583226 (ISSN), DOI 10.1063/9.0000165
Примечания : Cited References: 22. - The electron microscopy and magnetic resonance study was carried out on the equipment of the Krasnoyarsk Territorial Center for Collective Use, Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences. This work was supported by the Council of the President of the Russian Federation for State Support of Young Scientists and Leading Scientific Schools (project no. MK-1263.2020.3). The research was funded by RFBR, Krasnoyarsk Territory and Krasnoyarsk Regional Fund of Science, project number 20-42-242902
Аннотация: The effect of magnetic nanoparticles coated with arabinogalactan on the viability of Ehrlich ascites carcinoma (EAC) cells was studied. The nanoparticles were studied by transmission electron microscopy, Mossbauer spectroscopy, IR spectroscopy, and ferromagnetic resonance. A correlation between the proportion of dead EAC cells in suspension and the intensity of the EPR signal of dinitrosyl iron complexes was found. This result may be due to the presence of NO molecules.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Krasikov A. A., Knyazev Yu. V., Balaev D. A., Velikanov D. A., Stolyar S. V., Mikhlin Yu. L., Yaroslavtsev R. N., Iskhakov R. S.
Заглавие : Interparticle magnetic interactions and magnetic field dependence of superparamagnetic blocking temperature in ferrihydrite nanoparticle powder systems
Место публикации : Phys. B: Condens. Matter. - 2023. - Vol. 660. - Ст.414901. - ISSN 09214526 (ISSN), DOI 10.1016/j.physb.2023.414901. - ISSN 18732135 (eISSN)
Примечания : Cited References: 66. - This study was supported by his work was supported by the Russian Science Foundation, project no. 22-72-00134
Аннотация: In this study, nanoparticles of initial synthetic ferrihydrite have been coated with arabinogalactan. The synthesized series of samples with different degrees of coverage of particles has been characterized by X-ray photoelectron spectroscopy, Mossbauer spectroscopy, transmission electron microscopy and magnetometry. The superparamagnetic blocking temperature decreases monotonically with an increase in the degree of coverage of ferrihydrite particles, which is unambiguously related to the different role of the interparticle magnetic interactions in the investigated powder systems. Analysis of the field dependence of the blocking temperature within the random anisotropy model has shown that an increase in the degree of coverage of ferrihydrite particles leads to a decrease in the size of a cluster in which the behaviors of the nanoparticle magnetic moments are correlated. The results obtained have shown the possibility of effective control of the strength of magnetic interparticle interactions in powder ferrihydrite systems by coating nanoparticles with arabinogalactan.
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Stolyar S. V., Chekanova L. A., Cheremiskina E. V., Bayukov O. A., Yaroslavtsev R. N., Iskhakov R. S.
Заглавие : Magnetic coatings of Fe synthesized with arabinogalactan
Коллективы : Российская академия наук, Уральское отделение РАН, Институт физики металлов им. М. Н. Михеева Уральского отделения РАН, Уральский федеральный университет им. первого Президента России Б.Н. Ельцина, Российский фонд фундаментальных исследований, Euro-Asian Symposium "Trends in MAGnetism", "Trends in MAGnetism", Euro-Asian Symposium
Место публикации : Euro-asian symposium "Trends in magnetism" (EASTMAG-2019): Book of abstracts/ чл. конс. ком.: S. G. Ovchinnikov, N. V. Volkov [et al.] ; чл. прогр. ком. D. M. Dzebisashvili [et al.]. - 2019. - Vol. 2. - Ст.M.P10. - P.504-505. - ISBN 978-5-9500855-7-4 (Шифр В33/E12-125657784)
Примечания : Cited References: 4. - The reported study was carried out with the financial support of the Russian Foundation for Fundamental Research, the Government of the Krasnoyarsk Territory, the Krasnoyarsk Territory Fund for Support of Scientific and Technical Activity in the framework of scientific Project No. 18-43-243003. The work is supported by the Special Program of the Ministry of Education and Science of the Russian Federation for the Siberian Federal University
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Yaroslavtsev R. N., Stolyar S. V., Chekanova L. A., Cheremiskina E. V., Vazhenina I. G.
Заглавие : Magnetic coatings of transition metals synthesized using arabinogalactan
Коллективы : International Baltic Conference on Magnetism: focus on nanobiomedicine and smart materials, Балтийский федеральный университет им. И. Канта
Место публикации : 4th International Baltic Conference on Magnetism (IBCM 2021): Book of abstracts. - 2021. - P.217
Примечания : Cited References: 2
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Stolyar S. V., Vazhenina I. G., Yaroslavtsev R. N., Chekanova L. A., Cheremiskina E., Mikhlin Y.
Заглавие : Magnetic composite coatings FeC and NiC synthesized with arabinogalactan
Место публикации : IEEE Magn. Lett. - 2022. - Vol. 13. - Ст.2503505. - ISSN 1949307X (ISSN), DOI 10.1109/LMAG.2022.3164631
Примечания : Cited References: 23. - This work was supported by Russian Foundation for Basic Research, Krasnoyarsk Territory and Krasnoyarsk Regional Fund of Science under Project 20-42-240010. The authors thank the Center of Collective Use of the Federal Research Center, Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences for the provided equipment
Аннотация: In this work, we investigated the ferromagnetic resonance spectra of metal/carbon composite coatings. FeC and NiC coatings were synthesized by electroless deposition using polysaccharide arabinogalactan. An analysis of the angular dependences of the resonance field showed that the coatings consist of three magnetic phases separated by a nonmagnetic phase of carbon.
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10.

Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Stolyar S. V., Chekanova L. A., Yaroslavtsev R. N., Komogortsev S. V., Gerasimova Yu. V., Bayukov O. A., Volochaev M. N., Iskhakov R. S., Garanzha I. V., Kolovskaya O. S., Bairmani M. Sh., Zamay T. N.
Заглавие : Magnetic nanoconstructions of iron oxides coated with arabinogalactan functionalized with DNA aptamer
Коллективы : International Scientific Conference "Conference on Applied Physics, Information Technologies and Engineering"
Место публикации : J. Phys. Conf. Ser. - 2019. - Vol. 1399. - Ст.022026. - ISSN 1742-6588, DOI 10.1088/1742-6596/1399/2/022026. - ISSN 1742-6596 (eISSN)
Примечания : Cited References: 6
Предметные рубрики: Applied Physics
Аннотация: New composite nanoparticles for biomedical applications have been manufactured. The particles consist of an anisomeric magnetite core coated with arabinogalactan and are functionalized with cameras for As-14 ascites cells (Ehrlich carcinoma). The binding of ascitic Ehrlich carcinoma cells to magnetic nanoparticles was evaluated using fluorescence microscopy.
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