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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Sokolov A. Е., Lukyanenko A. V., Zabluda V. N., Borus A. A., Zamay G. S., Zamay T. N., Luzan N., Zamay S. S.
Заглавие : Aptamer modified Au/Ni/Au nanodiscs for magnetomechanical cell surgery
Коллективы : International Baltic Conference on Magnetism, Балтийский федеральный университет им. И. Канта
Место публикации : V International Baltic Conference on Magnetism. IBCM: Book of abstracts. - 2023. - P.12
Примечания : Cited References: 3
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Sokolov A. Е., Lukyanenko A. V., Moryachkov R. V., Zabluda V. N., Borus A. A., Zamay T., Luzan N. A., Galeev R. G., Masyugin A. N., Zelenov F. V., Zamay S. S.
Заглавие : Biofunctionaized magnetic nanodiscs applied in medicine
Коллективы : "Magnetic nanomaterials in biomedicine: synthesis and functionalization", International conference
Место публикации : 1st International Conference APRICOT 2023: book of abstracts. - 2023. - P.47-48
Примечания : Cited References: 4. - Красноярский рег. фонд науки, № 2022060108781
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Smolyarova T. E., Lukyanenko A. V., Tarasov A. S., Sokolov A. Е.
Заглавие : Dip-Pen Nanolithography method for fabrication of biofunctionalized magnetic nanodiscs applied in medicine
Коллективы : International Symposium on Nanostructures - Physics and Technology , Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund [17-42-240080, 16-42-243046, 16-42-242036]; Russian Federation [NSh-7559.2016.2]
Место публикации : Semiconductors. - 2018. - Vol. 52: 25th International Symposium on Nanostructures - Physics and Technology (Jun 26-30, 2017, Saint Petersburg, Russia), Is. 5. - P.675-677. - ISSN 1063-7826, DOI 10.1134/S1063782618050305. - ISSN 1090-6479(eISSN)
Примечания : Cited References:22. - The study was funded by Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research project nos. 17-42-240080, 16-42-243046, 16-42-242036 and the Grant of the President of the Russian Federation no. NSh-7559.2016.2.
Предметные рубрики: DRUG-DELIVERY
FORCE MICROSCOPY
NANOPARTICLES
HYPERTHERMIA
THERAPY
Аннотация: The magnetic properties of ferromagnetic nanodiscs coated with gold, manufactured using the Dip-Pen Nanolithography method, and were studied by atomic-force and magnetic force microscopy methods. The magnetic discs (dots) are represented as nanoagents (nanorobots) applied in medicine for the cancer cell destruction. The motivation of this work stem from the necessity of the understanding of the magnetization distribution in ferromagnetic discs that is crucial for their application in biomedicine. We have performed the theoretical calculations in order to compare the theoretical image contrast to experimental results. Herein, we report about the fabrication and analysis of biocompatible ferromagnetic nanodiscs with the homogenous magnetized state.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Smolyarova T. E., Lukyanenko A. V., Tarasov A. S., Sokolov A. Е.
Заглавие : Dip-Pen Nanolithography method for fabrication of biofunctionalized magnetic nanodiscs applied in medicine
Коллективы : International Symposium on Nanostructures - Physics and Technology , Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund [17-42-240080, 16-42-243046, 16-42-242036]; Russian Federation [NSh-7559.2016.2]
Место публикации : Физ. и техника полупроводников. - 2018. - Т. 52: 25th International Symposium on Nanostructures - Physics and Technology (Jun 26-30, 2017, Saint Petersburg, Russia), Вып. 5. - с.528. - ISSN 0015-3222, DOI 10.21883/FTP.2018.05.45872.61
Примечания : The study was funded by Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research project nos. 17-42-240080, 16-42-243046, 16-42-242036 and the Grant of the President of the Russian Federation no. NSh-7559.2016.2.
Аннотация: The magnetic properties of ferromagnetic nanodiscs coated with gold, manufactured using the Dip-Pen Nanolithography method, and were studied by atomic-force and magnetic force microscopy methods. The magnetic discs (dots) are represented as nanoagents (nanorobots) applied in medicine for the cancer cell destruction. The motivation of this work stem from the necessity of the understanding of the magnetization distribution in ferromagnetic discs that is crucial for their application in biomedicine. We have performed the theoretical calculations in order to compare the theoretical image contrast to experimental results. Herein, we report about the fabrication and analysis of biocompatible ferromagnetic nanodiscs with the homogenous magnetized state.
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Orlov V. A., Patrin G. S., Orlova I. N.
Заглавие : Dynamics of magnetization in an array of three-layer nanodiscs
Коллективы : Российская академия наук, Уральское отделение РАН, Институт физики металлов им. М. Н. Михеева Уральского отделения РАН, Уральский федеральный университет им. первого Президента России Б.Н. Ельцина, Российский фонд фундаментальных исследований, Euro-Asian Symposium "Trends in MAGnetism", "Trends in MAGnetism", Euro-Asian Symposium
Место публикации : Euro-asian symposium "Trends in magnetism" (EASTMAG-2019): Book of abstracts/ чл. конс. ком.: S. G. Ovchinnikov, N. V. Volkov [et al.] ; чл. прогр. ком. D. M. Dzebisashvili [et al.]. - 2019. - Vol. 1. - Ст.D.P13. - P.385-386. - ISBN 978-5-9500855-7-4 (Шифр В33/E12-125657784)
Примечания : Cited References: 2. - The research is done with the financial support of the Russian Foundation for Basic Research in the framework of Project No. 18-02-00161
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Orlov V. A., Patrin G. S., Orlova I. N.
Заглавие : Dynamics of magnetization in an array of three-layer nanodiscs
Коллективы : Euro-Asian Symposium "Trends in MAGnetism"
Место публикации : J. Phys. Conf. Ser. - 2019. - Vol. 1389, Is. 1. - Ст.012005. - ISSN 1742-6588, DOI 10.1088/1742-6596/1389/1/012005. - ISSN 1742-6596 (eISSN)
Примечания : Cited References: 27. - The reported study was funded by RFBR according to the research project no. 18-02-00161.
Аннотация: The paper studies associated motion of magnetic vortices in a triple-layer FM/NM/FM disc array. The connection of magnetic layers' magnetization inside of one disc and between the discs is assured by magnetostatic interaction. The frequencies of magnetic vortex resonant motion have been calculated analytically and resonant curves for the arrays with different alternation of magnetic vortex polarity and chirality have been constructed. It has been shown that despite of a small value of the core magnetic moments, taking their interaction into account leads to a small but significant splitting of the resonant frequency.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Zamay T. N., Prokopenko V. S., Zamay S. S., Lukyanenko K. A., Kolovskaya O. S., Orlov V. A., Zamay G. S., Galeev R. G., Narodov A. A., Kichkailo A. S.
Заглавие : Magnetic nanodiscs—A new promising tool for microsurgery of malignant neoplasms
Место публикации : Nanomaterials. - 2021. - Vol. 11, Is. 6. - Ст.1459. - ISSN 20794991 (ISSN), DOI 10.3390/nano11061459
Примечания : Cited References: 78. - The research was funded by Russian Foundation for Basic Research (RFBR) according to the project No. 20-02-00696, P.I. Vladimir S. Prokopenko. This work was partially supported by the grant of the Russian Science Foundation, project No. 19-74-00099 for Galina S. Zamay
Аннотация: Magnetomechanical therapy is one of the most perspective directions in tumor micro-surgery. According to the analysis of recent publications, it can be concluded that a nanoscalpel could become an instrument sufficient for cancer microsurgery. It should possess the following properties: (1) nano-or microsized; (2) affinity and specificity to the targets on tumor cells; (3) remote control. This nano-or microscalpel should include at least two components: (1) a physical nanostructure (particle, disc, plates) with the ability to transform the magnetic moment to mechanical torque; (2) a ligand—a molecule (antibody, aptamer, etc.) allowing the scalpel precisely target tumor cells. Literature analysis revealed that the most suitable nanoscalpel structures are anisotropic, magnetic micro-or nanodiscs with high-saturation magnetization and the absence of remanence, facilitating scalpel remote control via the magnetic field. Additionally, anisotropy enhances the transmigration of the discs to the tumor. To date, four types of magnetic microdiscs have been used for tumor destruction: synthetic antiferromagnetic P-SAF (perpendicular) and SAF (in-plane), vortex Py, and three-layer non-magnetic–ferromagnet–non-magnetic systems with flat quasi-dipole magnetic structures. In the current review, we discuss the biological effects of magnetic discs, the mechanisms of action, and the toxicity in alternating or rotating magnetic fields in vitro and in vivo. Based on the experimental data presented in the literature, we conclude that the targeted and remotely controlled magnetic field nanoscalpel is an effective and safe instrument for cancer therapy or theranostics.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Zamay S. S., Narodov A. A., Galeev R. G., Prokopenko V. S., Sokolov A. Е., Borus A. A., Zabluda V. N., Lukyanenko A. V., Baron F. A., Garifullin V. F., Masyugin A. N., Zelenov F. V., Grek D. S., Voronkovskii I. I., Gorbushin A., Kolovskaya O. S., Lukyanenko K. A., Nikolaeva E. D., Luzan N. A., Kichkailo A. S.
Заглавие : "Smart" nanoscalpel for microsurgery of glial tumors of the human brain
Место публикации : Sib. Med. Rev. - 2022. - Is. 5. - P.109-110. - ISSN 18199496 (ISSN), DOI 10.20333/25000136-2022-5-109-110; Сиб. мед. обозрение
Примечания : Cited References: 2. - This research was funded by the Regional State Autonomous Institution "Krasnoyarsk Regional Fund for Support of Scientific and Scientific and Technical Activities", Competition of scientific, technical and innovative projects in the interests of the first world-class climate scientific and educational center "Yenisei Siberia", grant “Carrying out applied research and development aimed at creating technologies for the production of nanoscalpels based on magnetic nanodisks for microsurgery of glial brain tumors” № 2022060108781 and with the support of a partner company JSC «NPP «Radiosviaz»
Аннотация: We studied the effectiveness of magnetomechanical therapy in the treatment of brain glial tumors using magnetic nanodiscs functionalized with DNA aptamers to human brain tumor glial cells. Materials and methods. The formation of a model of human glioblastoma was carried out by intracranial injection of tumor cells of glioblastoma obtained from a patient with glioblastoma. Antitumor therapy was carried out using nanodiscs modified with the Gli233 aptamer. The growth of the glial tumor was monitored using NMR tomography. Results and discussion. Therapy of a glial tumor during 4 sessions of magnetomechanical therapy using a "smart" nanoscalpel in MF (10Hz, 100Oe) led to a significant reduction in its size, while glial tumors in mice that were treated with nanodiscs modified with nonspecific aptamers continued to increase in size. Conclusion. Microsurgery using three-layer magnetic nanodisks with a quasi-dipole structure (Au/Ni/Au) modified with the specific for glial cells Gli233 aptamer (“smart” nanoscalpel) is effective for the treatment of human glial tumors in the brain.
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Zakomirnyi V. I., Rasskazov I. L., Gerasimov V. P., Ershov A. E., Ågren H., Polyutov S. P., Karpov S. V.
Заглавие : Ultra-narrow surface lattice resonances in periodic structures of refractory titanium nitride nanodiscs
Коллективы : Novel Optical Materials and Applications, Topical Meeting, OSA Optics and Photonics Congress
Место публикации : 14th Topical Meeting Novel Optical Materials and Applications: program. - 2018. - Polaritonics. - Ст.NOW4J.3. - P.85
Аннотация: We show that regular arrays of TiN nanodiscs support high-Q surface lattice resonances at telecom range. The obtained data open new prospects for utilization of refractory TiN in new photonics interconnects operating at high temperatures.
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