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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Stan S., Balasoiu M., Cristescu C. P., Stolyar S. V., Iskhakov R. S., Raikher Yu. L.
Заглавие : 2nd Fractional Brownian motion simulation for the fractal properties of ferryhidrite nanoparticles
Коллективы : "Complex and magnetic soft matter systems: physico-mechanical properties and structure", International summer school and workshop
Место публикации : 2nd International summer school and workshop complex and magnetic soft matter systems: physico-mechanical properties and structure: books of abstacs. - 2014. - P.78-79
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Tyumentseva A. V., Tyutrina E. S., Stolyar S. V., Yaroslavtsev R. N., Velikanov D. A.
Заглавие : Aminated magnetic nanoparticles for epithelial cell separation
Коллективы : International Baltic Conference on Magnetism: focus on nanobiomedicine and smart materials, Балтийский федеральный университет им. И. Канта
Место публикации : 4th International Baltic Conference on Magnetism (IBCM 2021): Book of abstracts. - 2021. - P.208
Примечания : This work was supported by Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research projects No. 20-42-242902 and by the Council of the President of the Russian Federation for State Support of Young Scientists and Leading Scientific Schools (project no. MK-1263.2020.3). We are grateful to the Center of collective use of FRC KSC SB RAS for the provided equipment.
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Tyumentseva A. V., Yaroslavtsev R. N., Stolyar S. V., Komogortsev S. V., Velikanov D. A., Gerasimova Yu. V., Knyazev Yu. V.
Заглавие : Aminated magnetic nanoparticles functionalized with antibodies for cell separation
Коллективы : Российская академия наук, Физико-технический институт им. Е.К. Завойского ФИЦ Казанского научного центра РАН, Казанский (Приволжский) федеральный университет, Euro-Asian Symposium "Trends in MAGnetism", "Trends in MAGnetism", Euro-Asian Symposium
Место публикации : VIII Euro-Asian symposium "Trends in magnetism" (EASTMAG-2022): Book of abstracts/ program com. S. G. Ovchinnikov [et al.]. - 2022. - Vol. 2, Sect. M: Magnetism in biology and medicine. - Ст.M.P10. - P.442-443. - ISBN 978-5-94469-051-7
Примечания : Cited References: 2. - The study was supported by the Russian Science Foundation and the Krasnoyarsk Region Science and Technology Support Fund, grant No. 22-14-20020
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Вид документа : Статья из сборника (выпуск продолж. издания)
Шифр издания :
Автор(ы) : Latyshev N. V., Kryukova O. V., Pyankov V. F., Stolyar S. V.
Заглавие : Analysis of Ehrlich ascites carcinoma with electron paramagnetic resonance
Коллективы : IEEE Ural-Siberian Conference on Computational Technologies in Cognitive Science, Genomics and Biomedicine, Урало-Сибирская конференция по вычислительным технологиям в когнитивной науке, геномике и биомедицине, Институт цитологии и генетики СО РАН
Место публикации : IEEE Ural-Siberian conference on computational technologies in cognitive science, genomics and biomedicine (CSGB). - 2021. - Ст.9496012. - P.290-293. - DOI 10.1109/CSGB53040.2021.9496012
Примечания : Cited References: 10
Аннотация: The study was aimed to reveal the dependence of changes in the content of metal-containing proteins and freeradical forms in a suspension of the experimental tumor in different periods of tumor growth using electron paramagnetic resonance. The object of the study was Ehrlich's ascites carcinoma, an experimental undifferentiated tumor, which is used to study various aspects of tumor development under external influences. Ehrlich ascites carcinoma was inoculated into the peritoneal cavity of laboratory mice. We believe that the determination of the concentrations of metal-containing proteins and free-radical forms using this method may be an important prognostic parameter for assessing the state of the tumor. Changes in metabolism will inevitably affect the functionality of cells and, as a consequence, the dynamics of tumor growth. The results of the study showed that metalcontaining proteins belonging to ascites plasma, such as transferrin, ferritin and ceruloplasmin, do not undergo significant changes. The signal from molybdenum-containing proteins also does not change at the stages of experimental tumor growth under consideration. However, in the course of this experiment, it was possible to record a slight decrease in the intensity of the formation of denitrosyl iron complexes with the development of a tumor in the body.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Stolyar S. V., Balaev D. A., Ladygina V. P., Dubrovskiy A. A., Krasikov A. A., Popkov S. I., Bayukov O. A., Knyazev Yu. V., Yaroslavtsev R. N., Volochaev M. N., Iskhakov R. S., Dobretsov K. G., Morozov E. V., Falaleev O. V., Inzhevatkin E. V., Kolenchukova O. A., Chizhova I. A.
Заглавие : Bacterial ferrihydrite nanoparticles: preparation, magnetic properties, and application in medicine
Место публикации : J. Supercond. Novel Magn. - 2018. - Vol. 31, Is. 8. - P.2297-2304. - ISSN 15571939 (ISSN), DOI 10.1007/s10948-018-4700-1
Примечания : Cited References: 37. - The electron microscopy examination was carried out at the Center for Collective Use of the Krasnoyarsk Scientific Center of the Siberian Branch of the Russian Academy of Sciences (Krasnoyarsk, Russia).
Ключевые слова (''Своб.индексиров.''): nanoparticles--ferrihydrite--magnetic properties--drug delivery
Аннотация: Nanoparticles of antiferromagnetically ordered materials acquire the uncompensated magnetic moment caused by defects and surface effects. A bright example of such a nano-antiferromagnet is nanoferrihydrite consisting of particles 2–5 nm in size, the magnetic moment of which amounts to hundreds of Bohr magnetons per particle. We present a brief review of the studies on magnetic properties of ferrihydrite produced by bacteria. Special attention is focused on the aspects of possible biomedical applications of this material, i.e., the particle elimination, toxicity, and possible use for targeted drug delivery.
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Stolyar S. V., Balaev D. A., Ladygina V. P., Dubrovskiy A. A., Krasikov A. A., Popkov S. I., Bayukov O. A., Yaroslavtsev R. N., Volochaev M. N., Iskhakov R. S., Dobretsov K. G., Falaleev O.V., Chizhova I. A.
Заглавие : Bacterial ferrihydrite nanoparticles: preparation, magnetic properties, and application in medicine
Коллективы : Moscow International Symposium on Magnetism, Московский государственный университет им. М.В. Ломоносова, Российский фонд фундаментальных исследований
Место публикации : Moscow Int. Symp. on Magnet. (MISM-2017): 1-7 July 2017 : book of abstracts. - 2017. - Ст.3RP-O-10. - P.417
Примечания : Cited References: 8. - Support by the Special Program for Siberian Federal University of the Ministry of Education and Science of the Russian Federation is acknowledged
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Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Stolyar S. V., Bayukov O. A., Ladygina V. P., Ishchenko L. A., Iskhakov R. S.
Заглавие : Biogenic ferrihydrite nanoparticles doped with gadolinium
Коллективы : Euro-Asian Symposium "Trends in MAGnetism": Nanomagnetism
Место публикации : V Euro-Asian simposium "Trend in MAGnetism": Nanomagnetism: abstracts. - Vladivostok: FEFU, 2013. - С. 232. - ISBN 978-5-7444-3124-2
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Cazacu, Nicoleta, Chilom, Claudia G., Iftimie, Sorina, Balasoiu, Maria, Ladygina, Valentina P., Stolyar S. V., Orelovich, Oleg L., Kovalev, Yuriy S., Rogachev, Andrey V.
Заглавие : Biogenic ferrihydrite nanoparticles produced by Klebsiella oxytoca: Characterization, physicochemical properties and bovine serum albumin interactions
Место публикации : Nanomaterials. - 2022. - Vol. 12, Is. 2. - Ст.249. - ISSN 2079-4991(eISSN), DOI 10.3390/nano12020249
Примечания : Cited References: 59. - This research was funded by JINR Themes 02-1-1107-2011/2021, 04-5-1131-2017/2021 and 04-4-1133-2018/2023 and with the financial support of the RO-JINR Projects Nos. 366/11.05.2021 (items 7, 86, 97) and 365/11.05.2021 (items 8, 87 and 98). This work also benefited from the use of the SasView application, originally developed under NSF Award DMR-0520547. SasView also contains the code developed with funding from the EU Horizon 2020 program under the SINE2020 project Grant No 654000. The APC was funded by JINR Theme 02-1-1107-2011/2021, Project No. 366/11.05.2021, item 7. This study used the infrastructure of the Applied Genetics Resource Facility of MIPT (Suport Grant 075-15-2021-684)
Предметные рубрики: MAGNETIC-PROPERTIES
REDUCTION
MOSSBAUER
FERRITIN
DOCKING
BINDING
Аннотация: The synthesis of nanoparticles inside microorganisms is an economical alternative to chemical and physical methods of nanoparticle synthesis. In this study, ferrihydrite nanoparticles synthesized by Klebsiella oxytoca bacterium in special conditions were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDS), small-angle X-ray (SAXS), UV-Vis spectroscopy, fluorescence, fluorescence resonance energy transfer (FRET), and molecular docking. The morphology and the structure of the particles were characterized by means of SEM and SAXS. The elemental content was determined by means of the EDS method. The absorption properties of the ferrihydrite nanoparticles were investigated by UV-Vis spectroscopy. The binding mechanism of the biogenic ferrihydrite nanoparticles to Bovine Serum Albumin (BSA) protein, studied by fluorescence, showed a static and weak process, combined with FRET. Protein denaturation by temperature and urea in the presence of the ferrihydrite nanoparticles demonstrated their influence on the unfolding process. The AutoDock Vina and UCSF Chimera programs were used to predict the optimal binding site of the ferrihydrite to BSA and to find the location of the hydrophobic cavities in the sub-domain IIA of the BSA structure.
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Вид документа : Статья из журнала
Шифр издания :
Автор(ы) : Stolyar S. V., Kolenchukova, Oksana A., Boldyreva, Anna V., Kudryasheva, Nadezda S., Gerasimova Yu. V., Krasikov A. A., Yaroslavtsev R. N., Bayukov O. A., Ladygina, Valentina P., Birukova, Elena A.
Заглавие : Biogenic ferrihydrite nanoparticles: Synthesis, properties in vitro and in vivo testing and the concentration effect
Коллективы : Russian Foundation for Basic ResearchRussian Foundation for Basic Research (RFBR); Government of the Krasnoyarsk Territory; Regional Science Foundation [20-416-242907]
Место публикации : Biomedicines. - 2021. - Vol. 9, Is. 3. - Ст.323. - ISSN 2227-9059(eISSN), DOI 10.3390/biomedicines9030323
Примечания : Cited References: 52. - This research was funded by the Russian Foundation for Basic Research, the Government of the Krasnoyarsk Territory and the Regional Science Foundation, grant number 20-416-242907
Аннотация: Biogenic ferrihydrite nanoparticles were synthesized as a result of the cultivation of Klebsiella oxytoca microorganisms. The distribution of nanoparticles in the body of laboratory animals and the physical properties of the nanoparticles were studied. The synthesized ferrihydrite nanoparticles are superparamagnetic at room temperature, and the characteristic blocking temperature is 23-25 K. The uncompensated moment of ferrihydrite particles was determined to be approximately 200 Bohr magnetons. In vitro testing of different concentrations of ferrihydrite nanoparticles for the functional activity of neutrophilic granulocytes by the chemiluminescence method showed an increase in the release of primary oxygen radicals by blood phagocytes when exposed to a minimum concentration and a decrease in secondary radicals when exposed to a maximum concentration. In vivo testing of ferrihydrite nanoparticles on Wister rats showed that a suspension of ferrihydrite nanoparticles has chronic toxicity, since it causes morphological changes in organs, mainly in the spleen, which are characterized by the accumulation of hemosiderin nanoparticles (stained blue according to Perls). Ferrihydrite can also directly or indirectly stimulate the proliferation and intracellular regeneration of hepatocytes. The partial detection of Perls-positive cells in the liver and kidneys can be explained by the rapid elimination from organs and the high dispersion of the nanomaterial. Thus, it is necessary to carry out studies of these processes at the systemic level, since the introduction of nanoparticles into the body is characterized by adaptive-proliferative processes, accompanied by the development of cell dystrophy and tension of the phagocytic system.
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10.

Вид документа : Статья из сборника (однотомник)
Шифр издания :
Автор(ы) : Stolyar S. V., Ishchenko L. A., Ladygina V. P., Bayukov O. A., Iskhakov R. S., Antonov A. I.
Заглавие : Biogenic nanoparticles of ferrihydrites
Коллективы : "Complex and magnetic soft matter systems: physico-mechanical properties and structure", International summer school and workshop
Место публикации : 2nd International summer school and workshop complex and magnetic soft matter systems: physico-mechanical properties and structure: books of abstacs. - 2014. - P.11
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