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1.
Magnetic coatings of
transition metals synthesized using
arabinogalactan
/ R. N. Yaroslavtsev, S. V. Stolyar, L. A. Chekanova [et al.]> //
4th International Baltic Conference on Magnetism (IBCM 2021) : Book of abstracts. - 2021. - P. 217. - Cited References: 2
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Держатели документа:
Kirensky Institute of Physics, Federal Research Center KSC SB RAS
Доп.точки доступа:
Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Stolyar, S. V.; Столяр, Сергей Викторович; Chekanova, L. A.; Чеканова, Лидия Александровна; Cheremiskina, E. V.; Vazhenina, I. G.; Важенина, Ирина Георгиевна; International Baltic Conference on Magnetism: focus on nanobiomedicine and smart materials(4 ; 2021 ; Aug. 29-Sept. 2 ; Svetlogorsk, Russia); Балтийский федеральный университет им. И. Канта
}
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2.
Magnetic composite coatings
FeC and NiC synthesized with
arabinogalactan
/ S. Stolyar, I. Vazhenina, R. Yaroslavtsev [et al.]> // IEEE Magn. Lett. - 2022. -
Vol. 13
. - Ст. 2503505,
DOI
10.1109/LMAG.2022.3164631. - Cited References: 23. - This work was supported by Russian Foundation for Basic Research, Krasnoyarsk Territory and Krasnoyarsk Regional Fund of Science under Project 20-42-240010. The authors thank the Center of Collective Use of the Federal Research Center, Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences for the provided equipment . - ISSN 1949-307X
Кл.слова (ненормированные):
magnetism in solids
--
electroless deposition
--
magnetic coatings
--
ferromagnetic resonance
Аннотация:
In this work, we investigated the ferromagnetic resonance spectra of metal/carbon composite coatings. FeC and NiC coatings were synthesized by electroless deposition using polysaccharide
arabinogalactan
. An analysis of the angular dependences of the resonance field showed that the coatings consist of three magnetic phases separated by a nonmagnetic phase of carbon.
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Держатели документа:
Krasnoyarsk Scientific Center, Federal Research Center KSC SB RAS, 660036 Krasnoyarsk, Russia
Kirensky Institute Of Physics, Federal Research Center Ksc Sb Ras, Krasnoyarsk, 660036, Russian Federation
Siberian Federal University, Krasnoyarsk, 660041, Russian Federation
Institute Of Chemistry And Chemical Technology, Federal Research Center Ksc Sb Ras, Krasnoyarsk, 660036, Russian Federation
Доп.точки доступа:
Stolyar, S. V.; Столяр, Сергей Викторович; Vazhenina, I. G.; Важенина, Ирина Георгиевна; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Chekanova, L. A.; Чеканова, Лидия Александровна; Cheremiskina, E.; Mikhlin, Y.
}
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3.
Influence of magnetic
nanoparticles on cells of Ehrlich ascites carcinoma / S. V. Stolyar, O. V. Kryukova, R. N. Yaroslavtsev [et al.]> // AIP Adv. - 2021. -
Vol. 11
,
Is. 1
. - Ст. 015019,
DOI
10.1063/9.0000165. - Cited References: 22. - The electron microscopy and magnetic resonance study was carried out on the equipment of the Krasnoyarsk Territorial Center for Collective Use, Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences. This work was supported by the Council of the President of the Russian Federation for State Support of Young Scientists and Leading Scientific Schools (project no. MK-1263.2020.3). The research was funded by RFBR, Krasnoyarsk Territory and Krasnoyarsk Regional Fund of Science, project number 20-42-242902 . - ISSN 2158-3226
Кл.слова (ненормированные):
High resolution transmission electron microscopy
--
Iron compounds
--
Arabinogalactan
--
Ehrlich ascites carcinoma
--
EPR signals
--
Iron complex
--
NO molecule
--
Ssbauer spectroscopies
--
Magnetic nanoparticles
Аннотация:
The effect of magnetic nanoparticles coated with
arabinogalactan
on the viability of Ehrlich ascites carcinoma (EAC) cells was studied. The nanoparticles were studied by transmission electron microscopy, Mossbauer spectroscopy, IR spectroscopy, and ferromagnetic resonance. A correlation between the proportion of dead EAC cells in suspension and the intensity of the EPR signal of dinitrosyl iron complexes was found. This result may be due to the presence of NO molecules.
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Держатели документа:
Krasnoyarsk Scientific Center, Federal Research Center Ksc Sb Ras, Krasnoyarsk, 660036, Russian Federation
Kirensky Institute of Physics, Federal Research Center Ksc Sb Ras, Krasnoyarsk, 660036, Russian Federation
Доп.точки доступа:
Stolyar, S. V.; Kryukova, O. V.; Yaroslavtsev, R. N.; Bayukov, O. A.; Баюков, Олег Артемьевич; Knyazev, Yu. V.; Князев, Юрий Владимирович; Gerasimova, Yu. V.; Герасимова, Юлия Валентиновна; Pyankov, V. F.; Latyshev, N. V.; Shestakov, N. P.; Шестаков, Николай Петрович
}
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4.
Структура и магнитные
свойства кобальт-никелевых покрытий, полученных с использованием арабиногалактана / Е. В. Черемискина, С. В. Столяр, Л. А. Чеканова [и др.]> //
Новое в магнетизме и магнитных материалах : сборник трудов XXIV международной конференции / прогр. ком.: Р. С. Исхаков, С. Г. Овчинников [и др.]. - 2021. -
Секция 9
: Магнитные пленки. - Ст. 9-86-89. - Библиогр.: 5
Перевод заглавия:
Structure and magnetic properties of cobaltnickel coatings synthesized using
arabinogalactan
Кл.слова (ненормированные):
магнитные покрытия
--
арабиногалактан
Аннотация:
Получены покрытия 3-d металлов из растворов солей в присутствии природного полисахарида арабиногалактана. Рассчитанные постоянные атомной решетки регистрируемых ГЦК и ГПУ структур соответствуют значениям характерным для сплава Co1-xNix, что свидетельствует об отсутствии твердого раствора металл-углерод.
The coatings of 3-d metals were obtained from salt solutions in the presence of the natural polysaccharide
arabinogalactan
. The calculated atomic lattice constants of the detected fcc and hcp structures correspond to the values characteristic of the Co1-xNix alloy, which indicates the absence of a metal-carbon solid solution.
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Держатели документа:
Институт физики им. Л.В. Киренского СО РАН
Доп.точки доступа:
Исхаков, Рауф Садыкович \прогр. ком.\; Iskhakov, R. S.; Овчинников, Сергей Геннадьевич \прогр. ком.\; Ovchinnikov, S. G.; Черемискина, Елена Владимировна; Столяр, Сергей Викторович; Stolyar, S. V.; Чеканова, Лидия Александровна; Chekanova, L. A.; Ярославцев, Роман Николаевич; Yaroslavtsev, R. N.; Исхаков, Рауф Садыкович; "Новое в магнетизме и магнитных материалах", международная конференция(24 ; 2021 ; 1-8 июля ; Москва); Научный совет по физике конденсированных сред РАН; МИРЭА - Российский технологический университет; Московский государственный университет им. М.В. Ломоносова; Магнитное общество России
}
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5.
Interparticle magnetic interactions
and magnetic field dependence of superparamagnetic blocking temperature in ferrihydrite nanoparticle powder systems / A. A. Krasikov, Yu. V. Knyazev, D. A. Balaev [et al.]> // Phys. B: Condens. Matter. - 2023. -
Vol. 660
. - Ст. 414901,
DOI
10.1016/j.physb.2023.414901. - Cited References: 66. - This study was supported by his work was supported by the Russian Science Foundation, project no. 22-72-00134 . - ISSN 0921-4526. - ISSN 1873-2135
Кл.слова (ненормированные):
Ferrihydrite nanoparticles
--
Interparticle magnetic interactions
--
Superparamagnetic blocking temperature
--
Coating
--
Arabinogalactan
Аннотация:
In this study, nanoparticles of initial synthetic ferrihydrite have been coated with
arabinogalactan
. The synthesized series of samples with different degrees of coverage of particles has been characterized by X-ray photoelectron spectroscopy, Mossbauer spectroscopy, transmission electron microscopy and magnetometry. The superparamagnetic blocking temperature decreases monotonically with an increase in the degree of coverage of ferrihydrite particles, which is unambiguously related to the different role of the interparticle magnetic interactions in the investigated powder systems. Analysis of the field dependence of the blocking temperature within the random anisotropy model has shown that an increase in the degree of coverage of ferrihydrite particles leads to a decrease in the size of a cluster in which the behaviors of the nanoparticle magnetic moments are correlated. The results obtained have shown the possibility of effective control of the strength of magnetic interparticle interactions in powder ferrihydrite systems by coating nanoparticles with
arabinogalactan
.
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Держатели документа:
Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Krasnoyarsk, 660036 Russia
Siberian Federal University, Krasnoyarsk, 660041, Russia
Krasnoyarsk Scientific Center, Federal Research Center KSC SB RAS, Krasnoyarsk, 660036, Russia
Institute of Chemistry and Chemical Technology, Federal Research Center KSC SB RAS, Krasnoyarsk, 660036 Russia
Доп.точки доступа:
Krasikov, A. A.; Красиков, Александр Александрович; Knyazev, Yu. V.; Князев, Юрий Владимирович; Balaev, D. A.; Балаев, Дмитрий Александрович; Velikanov, D. A.; Великанов, Дмитрий Анатольевич; Stolyar, S. V.; Столяр, Сергей Викторович; Mikhlin, Yu. L.; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Iskhakov, R. S.; Исхаков, Рауф Садыкович
}
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6.
Influence of
arabinogalactan
-coated
selenium nanoparticles on the formation of free radicals in Ehrlich ascites carcinoma cells / K. V. Shadrin, Yu. A. Yakovleva, O. V. Kryukova [et al.]> // BioNanoScience. - 2024. -
Vol. 14
,
Is. 1
. - P. 268-275,
DOI
10.1007/s12668-023-01251-6. - Cited References: 40 . - ISSN 2191-1630. - ISSN 2191-1649
Кл.слова (ненормированные):
Selenium
--
Nanoparticles
--
Microwave radiation
--
Antioxidant properties
--
Ehrlich ascitic carcinoma
Аннотация:
The antioxidant properties of selenium nanoparticles coated with
arabinogalactan
have been studied. The nanoparticles were characterized by transmission electron microscopy and infrared spectroscopy.
Arabinogalactan
-coated selenium nanoparticles were incubated together with Ehrlich ascitic carcinoma cells and then exposed to microwave radiation. The antioxidant properties of selenium nanoparticles were evaluated using chemiluminescent analysis. The viability of Ehrlich ascitic carcinoma cells under microwave irradiation and incubation with selenium nanoparticles was assessed by flow cytometry. Under conditions of exposure to experimental tumor cells of microwave radiation, the concentration of free radicals in the cells did not change. The effect of
arabinogalactan
-coated selenium nanoparticles on tumor cells is expressed as an increase in the delay time for the activation of the antioxidant system.
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Держатели документа:
Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, P. Zeleznyak street, 1, 660022, Krasnoyarsk, Russia
Krasnoyarsk Science Center, Federal Research Center KSC SB RAS, Akademgorodok 50, 660036, Krasnoyarsk, Russia
Siberian Federal University, Svobodny, 79, 660041, Krasnoyarsk, Russia
Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Akademgorodok 50, bld. 38, 660036, Krasnoyarsk, Russia
Institute of Chemistry and Chemical Technology, Federal Research Center KSC SB RAS, 660036, Krasnoyarsk, Russia
Доп.точки доступа:
Shadrin, K. V.; Yakovleva, Yu. A.; Kryukova, O. V.; Makarskaya, G. V.; Tarskikh, S. V.; Pyankov, V. F.; Pakhomova, V. G.; Gerasimova, Yu. V.; Герасимова, Юлия Валентиновна; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Vorobyev, S. A.; Stolyar, S. V.; Столяр, Сергей Викторович
}
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7.
Synthesis of transition
metal coatings using
arabinogalactan
/ S. V. Stolyar, L. A. Chekanova, E. V. Cheremiskina [et al.]> // Bull. Russ. Acad. Sci. Phys. - 2022. -
Vol. 86
,
Is. 5
. - P. 597-600,
DOI
10.3103/S1062873822050264. - Cited References: 19. - The study was supported by the Russian Foundation for Basic Research, the Government of the Krasnoyarsk Territory, and the Krasnoyarsk Regional Science Foundation (project no. 20-43-240003) . - ISSN 1062-8738
Кл.слова (ненормированные):
Alkalinity
--
Carbon
--
Coatings
--
Crystal structure
--
Alkaline media
--
Arabinogalactan
--
Carbon containing
--
Chemical compositions
--
Chemical deposition
--
Crystals structures
--
Graphite inclusions
--
Ni coating
--
Synthesised
--
X- ray diffractions
--
Transition metals
Аннотация:
Carbon-containing transition metal (Fe, Co, Ni) coatings are synthesized via chemical deposition with
arabinogalactan
. The crystal structure and chemical composition of the coatings are determined. Data from magnetometry and X-ray diffraction show that carbon is not included in the crystal lattice of a metal. Instead, it exists in the form of graphite inclusions. Degradation of
arabinogalactan
in an alkaline medium on the surface of a galvanic pair is investigated.
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Публикация на русском языке
Получение покрытий переходных металлов в присутствии арабиногалактана [Текст] / С. В. Столяр, Л. А. Чеканова, Е. В. Черемискина [и др.] // Изв. РАН. Сер. физич. - 2022. - Т. 86. № 5. - С. 711-715
Держатели документа:
Kirensky Institute of Physics, Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, 660036, Russian Federation
Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, 660036, Russian Federation
Siberian Federal University, Krasnoyarsk, 660041, Russian Federation
Institute of Chemistry and Chemical Technology, Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, 660036, Russian Federation
Ural Federal University, Yekaterinburg, 620075, Russian Federation
Доп.точки доступа:
Stolyar, S. V.; Столяр, Сергей Викторович; Chekanova, L. A.; Чеканова, Лидия Александровна; Cheremiskina, E. V.; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Taran, O. P.; Borovkova, V. S.; Malyar, Y. N.; Neznakhin, D. S.; Komogortsev, S. V.; Комогорцев, Сергей Викторович
}
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8.
Nucleic acid aptamers
increase the anticancer efficiency and reduce the toxicity of cisplatin-
arabinogalactan
conjugates in vivo / T. N. Zamay, A. K. Starkov, O. S. Kolovskaya [et al.]> // Nucleic Acid Ther. - 2022. -
Vol. 32
,
Is. 6
. - P. 497-506,
DOI
10.1089/nat.2022.0024. - Cited References: 42 . - ISSN 2159-3337. - ISSN 2159-3345
Кл.слова (ненормированные):
cisplatin
--
aptamer
--
arabinogalactan
--
cancer chemotherapy
--
ascites carcinoma
Аннотация:
Cisplatin is an effective drug for treating various cancer types. However, it is highly toxic for both healthy and tumor cells. Therefore, there is a need to reduce its therapeutic dose and increase targeted bioavailability. One of the ways to achieve this could be the coating of cisplatin with polysaccharides and specific carriers for targeted delivery. Nucleic acid aptamers could be used as carriers for the specific delivery of medicine to cancer cells. Cisplatin-
arabinogalactan
-aptamer (Cis-AG-Ap) conjugate was synthesized based on Cis-dichlorodiammineplatinum, Siberian larch
arabinogalactan
, and aptamer AS-42 specific to heat-shock proteins (HSP) 71?kDa (Hspa8) and HSP 90-beta (Hsp90ab1). The antitumor effect was estimated using ascites and metastatic Ehrlich tumor models. Cis-AG-Ap toxicity was assessed by blood biochemistry on healthy mice. Here, we demonstrated enhanced anticancer activity of Cis-AG-Ap and its specific accumulation in tumor foci. It was shown that targeted delivery allowed a 15-fold reduction in the therapeutic dose of cisplatin and its toxicity. Cis-AG-Ap sufficiently suppressed the growth of Ehrlich's ascites carcinoma, the mass and extent of tumor metastasis in vivo.
Arabinogalactan
and the aptamers promoted cisplatin efficiency by enhancing its bioavailability. The described strategy could be very promising for targeted anticancer therapy.
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Держатели документа:
Laboratory for Digital Controlled Drugs and Theranostics, Federal Research Center "Krasnoyarsk Research Center" of the Siberian Branch of the Russian Academy of Science, Krasnoyarsk, Russian Federation
Laboratory For Biomolecular and Medical Technologies, Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenecky, Krasnoyarsk, Russian Federation
Institute of Chemistry and Chemical Technology SB RAS, Federal Research Center "Krasnoyarsk Science Center SB RAS, Krasnoyarsk660036, Russian Federation
Department of Chemistry, Siberian Federal University, Krasnoyarsk, Russian Federation
Laboratory for Physics of Magnetic Phenomena, Kirensky Institute of Physics, Federal Research Center Krasnoyarsk Science Center SB RAS, Krasnoyarsk, Russian Federation
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON, Canada
Доп.точки доступа:
Zamay, T. N.; Starkov, A. K.; Kolovskaya, O. S.; Zamay, G. S.; Veprintsev, D. V.; Luzan, N.; Nikolaeva, E. D.; Lukyanenko, K. A.; Artyushenko, P. V.; Shchugoreva, I. A.; Glazyrin, Y. E.; Koshmanova, A. A.; Krat, A. V.; Tereshina, D. S.; Zamay, S. S.; Pats, Y. S.; Zukov, R. A.; Tomilin, F. N.; Томилин, Феликс Николаевич; Berezovski, M. V.; Kichkailo, A. S.
}
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9.
CoC films sinthezited
whis
arabinogalactan
/ S. V. Stolyar, R. N. Yaroslavtsev, L. A. Chekanova [et al.]> //
Nanostructures: physics and technology : proc. 28th Int. symp. - 2020. - Ст. NT.19. - P. 105-106. - Cited References: 1 . - ISBN 978-5-93634-066-6
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Доп.точки доступа:
Stolyar, S. V.; Столяр, Сергей Викторович; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Chekanova, L. A.; Чеканова, Лидия Александровна; Komogortsev, S. V.; Комогорцев, Сергей Викторович; Cheremiskina, E. V.; Neznakhin, D. S.; Iskhakov, R. S.; Исхаков, Рауф Садыкович; Nanostructures: Physics and Technology, International Symposium(28 ; 2020 ; 28 Sept.-2 Oct. ; Minsk, Belarus); Институт физики им. Б. И. Степанова НАН Беларуси; Санкт-Петербургский национальный исследовательский Академический университет Российской академии наук; Физико-технический институт им. А.Ф. Иоффе РАН; Научно-технологический центр микроэлектроники и субмикронных гетероструктур Российской академии наук
}
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10.
The Raman spectroscopy,
XRD, SEM, and AFM study of
arabinogalactan
sulfates obtained using sulfamic acid / B. N. Kuznetsov [et al.]> // Russ. J. Bioorgan. Chem. - 2017. -
Vol. 43
,
No. 7
. - P. 32-36,
DOI
10.1134/S106816201707010X. - Cited References: 9. - The work was financially supported by the Russian Foundation for Basic Research and the Government of the Krasnoyarsk krai (project no. 16-43-242083). . - ISSN 1068-1620
Кл.слова (ненормированные):
physicochemical investigation
--
sulfated
arabinogalactan
--
«green» synthesis
--
sulfamic acid
--
urea
Аннотация:
The structure of sodium salts of sulfated
arabinogalactan
(AG), obtained by sulfation of larch wood AG with sulfamic acid – urea mixture in the medium of 1,4-dioxane was investigated with the use of Raman spectroscopy, X-ray diffraction (XRD), scaning electron microscopy (SEM) and aromatic force microscopy (AFM) methods. The introduction of sulfate groups into the structure of AG was confirmed by appearance in Raman spectra new absorption bands characteristic for the deformation vibrations of d (SO3) at 420 cm-1 and d (O=S=O) at 588 cm-1, stretching vibrations n (C–O–S) at 822 cm-1, symmetric stretching vibrations ns (O=S=O) at 1076 cm-1, asymmetric stretching vibrations nas (О=S=O) at 1269 cm-1. According to XRD data the amorphization of
arabinogalactan
structure take place during it`s sulfation. The difference in the morphology of initial and sulfated arabinogalactans was established by SEM method. Initial arabinigalactan consists of particles of globular shape with size of 10–90 µm, but sulfates of AG – from particles of different shapes and sizes of 1–8 µm. According to AFM data the surface of film of
arabinogalactan
sulfates is formed by the rather homogeneous spherical particles with sizes near 70 nm. The mean-square value of the surface rounghness is equal to 33 nm.
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Публикация на русском языке
Исследование методами КР, РФА, РЭМ и АСМ сульфатов арабиногалактана, полученных с использованием сульфаминовой кислоты [Текст] / Б. Н. Кузнецов [и др.] // Хим. растит. сырья. - 2016. - № 4. - С. 43-48
Держатели документа:
Институт химии и химической технологии СО РАН
Сибирский федеральный университет
Институт физики им. Л. В. Киренского СО РАН
Доп.точки доступа:
Kuznetsov, B. N.; Vasil'eva, N. Yu.; Levdansky, A. V.; Karacharov, A. A.; Krylov, A. S.; Крылов, Александр Сергеевич; Mazurova, E. V.; Bondarenko, G. N.; Levdansky, V. A.; Kazachenko, A. S.
}
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11.
Magnetic nanoconstructions of
iron oxides coated with
arabinogalactan
functionalized with DNA aptamer / S. V. Stolyar [et al.]> // J. Phys. Conf. Ser. - 2019. -
Vol. 1399
. - Ст. 022026,
DOI
10.1088/1742-6596/1399/2/022026. - Cited References: 6 . - ISSN 1742-6588. - ISSN 1742-6596
Рубрики:
Applied Physics
Аннотация:
New composite nanoparticles for biomedical applications have been manufactured. The particles consist of an anisomeric magnetite core coated with
arabinogalactan
and are functionalized with cameras for As-14 ascites cells (Ehrlich carcinoma). The binding of ascitic Ehrlich carcinoma cells to magnetic nanoparticles was evaluated using fluorescence microscopy.
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Держатели документа:
Siberian Federal University, Krasnoyarsk, Russia
Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Krasnoyarsk, Russia
Krasnoyarsk Scientific Center, Federal Research Center KSC SB RAS Krasnoyarsk, Russia
Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenecki, Krasnoyarsk, 660022, Russia
Astrakhan State University, Tatisheva 20 A, Astrakhan, 414056, Russia
College of Biotechnology, Al-Qasim Green University, Iraq
Доп.точки доступа:
Stolyar, S. V.; Столяр, Сергей Викторович; Chekanova, L. A.; Чеканова, Лидия Александровна; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Komogortsev, S. V.; Комогорцев, Сергей Викторович; Gerasimova, Yu. V.; Герасимова, Юлия Валентиновна; Bayukov, O. A.; Баюков, Олег Артемьевич; Volochaev, M. N.; Волочаев, Михаил Николаевич; Iskhakov, R. S.; Исхаков, Рауф Садыкович; Garanzha, I. V.; Kolovskaya, O. S.; Bairmani, M. Sh.; Zamay, T. N.; International Scientific Conference "Conference on Applied Physics, Information Technologies and Engineering"(25-27 September 2019 ; Krasnoyarsk, Russian Federation)
}
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12.
Antitumor effect of
arabinogalactan
and platinum complex / A. K. Starkov [et al.]> // Dokl. Biochem. Biophys. - 2016. -
Vol. 467
,
Is. 1
. - P. 92-94,
DOI
10.1134/S1607672916020046. - Cited References: 7. - This study was supported by the Ministry of Education and Science of the Russian Federation (agreement no. 14.607.21.0104). This study was performed using the shared-access equipment center of the Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences. . - ISSN 1607-6729
РУБ
Biochemistry & Molecular Biology + Biophysics
Аннотация:
The article presents the results of investigation of antitumor properties of platinum–
arabinogalactan
complex. We showed the ability of the complex to inhibit the growth of Ehrlich ascites tumor cells. It is found that the distribution of the platinum–
arabinogalactan
complex is not specific only for tumor cells in mice. The complex was found in all tissues and organs examined (ascites cells, embryonic cells, kidney, and liver). The mechanism of action of the arabinogalactan–platinum complex may be similar to cisplatin as the complex is able to accumulate in tumor cells. © 2016, Pleiades Publishing, Ltd.
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Публикация на русском языке
Противоопухолевый эффект комплекса арабиногалактана с платиной [Текст] / А. К. Старков [и др.] // Докл. Акад. наук : Наука, 2016. - Т. 467 № 1. - С. 112-114
Держатели документа:
Institute of Chemistry and Chemical Technology, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, Russian Federation
Voino-Yasenetskii State Medical University, Ministry of Health of the Russian Federation, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk krai, Russian Federation
Siberian Federal University, Svobodnyi pr. 79, Krasnoyarsk, Russian Federation
Kirenskii Institute of Physics, Siberian Branch, Russian Academy of Sciences, Akademgorodok, Krasnoyarsk, Russian Federation
Доп.точки доступа:
Starkov, A. K.; Zamay, T. N.; Замай, Т. Н.; Savchenko, A. A.; Ingevatkin, E. V.; Titova, N. M.; Kolovskaya, O. S.; Коловская, О. С.; Luzan, N. A.; Silkin, P. P.; Kuznetsova, S. A.; Кузнецова, Светлана Алексеевна
}
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13.
Synthesis of metal
coatings using
arabinogalactan
and their magnetic properties / L. A. Chekanova [и др.]> //
Moscow Int. Symp. on Magnet. (MISM-2017) : 1-7 July 2017 : book of abstracts. - 2017. - Ст. 2PO-K-44. - P. 317. - Cited References: 2. - The research was carried out with the support of the regional state autonomous institution "Krasnoyarsk Regional Fund for Support of Scientific and Technical Activity" within the framework of participation in the event: Moscow International Symposium on Magnetism. This work was supported by the Russian Foundation for Basic Research, Grants № 16-03-00256, 16-03-00969. Support by the Special Program for Siberian Federal University of the Ministry of Education and Science of the Russian Federation is acknowledged
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Доп.точки доступа:
Chekanova, L. A.; Чеканова, Лидия Александровна; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Stolyar, S. V.; Столяр, Сергей Викторович; Iskhakov, R. S.; Исхаков, Рауф Садыкович; Moscow International Symposium on Magnetism(7 ; 2017 ; Jul. ; Moscow); Московский государственный университет им. М.В. Ломоносова; Российский фонд фундаментальных исследований
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14.
Aptamer-conjugated superparamagnetic ferroarabinogalactan
nanoparticles for targeted magnetodynamic therapy of cancer / O. S. Kolovskaya, T. N. Zamay, G. S. Zamay [et al.]> // Cancers. - 2020. -
Vol. 12
,
Is. 1
. - Ст. 216,
DOI
10.3390/cancers12010216. - Cited References: 46. - This research was funded by the Ministry of Science and Higher Education of the Russian Federation; project 0287-2019-0007 . - ISSN 2072-6694
Кл.слова (ненормированные):
aptamers
--
arabinogalactan
--
superparamagnetic ferroarabinogalactans
--
drug delivery
--
magnetodynamic therapy
--
magnetically induced cell disruption
--
magnetic resonance imaging
Аннотация:
Nanotechnologies involving physical methods of tumor destruction using functional oligonucleotides are promising for targeted cancer therapy. Our study presents magnetodynamic therapy for selective elimination of tumor cells in vivo using DNA aptamer-functionalized magnetic nanoparticles exposed to a low frequency alternating magnetic field. We developed an enhanced targeting approach of cancer cells with aptamers and
arabinogalactan
. Aptamers to fibronectin (AS-14) and heat shock cognate 71 kDa protein (AS-42) facilitated the delivery of the nanoparticles to Ehrlich carcinoma cells, and
arabinogalactan
(AG) promoted internalization through asialoglycoprotein receptors. Specific delivery of the aptamer-modified FeAG nanoparticles to the tumor site was confirmed by magnetic resonance imaging (MRI). After the following treatment with a low frequency alternating magnetic field, AS-FeAG caused cancer cell death in vitro and tumor reduction in vivo. Histological analyses showed mechanical disruption of tumor tissues, total necrosis, cell lysis, and disruption of the extracellular matrix. The enhanced targeted magnetic theranostics with the aptamer conjugated superparamagnetic ferroarabinogalactans opens up a new venue for making biocompatible contrasting agents for MRI imaging and performing non-invasive anti-cancer therapies with a deep penetrated magnetic field.
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Держатели документа:
Federal Research Center “Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Science”, 660036 Krasnoyarsk, Russia
Laboratory for Biomolecular and Medical Technologies, Faculty of Medicine, Krasnoyarsk State Medical University named after prof. V.F. Voino-Yasenecki, 660022 Krasnoyarsk, Russia
Irkutsk Institute of Chemistry named after A.E. Favorsky, the Siberian Branch of the Russian Academy of Sciences, 664033 Irkutsk, Russia
L.V. Kirensky Institute of Physics SB RAS—The Branch of Federal Research Center “Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences”, 660036 Krasnoyarsk, Russia
Laboratory of Advanced Materials and Technology, Tomsk State University, 634050 Tomsk, Russia
Institute of Chemistry and Chemical Technology SB RAS—The Branch of Federal Research Center “Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences”, 660036 Krasnoyarsk, Russia
School of Engineering Physics and Radio Electronics, Siberian Federal University, 660041 Krasnoyarsk, Russia
Research Center for Computational Design of Advanced Functional Materials (CD-FMat), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba 305-8568, Japan
School of Non-Ferrous Metals and Materials Science, Siberian Federal University, 660041 Krasnoyarsk, Russia
Faculty of Physics, Department of Magnetism, Lomonosov Moscow State University, 119991 Moscow, Russia
School of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada
Доп.точки доступа:
Kolovskaya, O. S.; Коловская, О. С.; Zamay, T. N.; Замай, Т. Н.; Zamay, G. S.; Замай, Галина Сергеевна; Babkin, V. A.; Medvedeva, E. N.; Neverova, N. A.; Kirichenko, A. K.; Zamay, S. S.; Замай, С. С.; Lapin, I. N.; Morozov, E. V.; Морозов, Евгений Владимирович; Sokolov, A. Е.; Соколов, Алексей Эдуардович; Narodov, A. A.; Fedorov, D. G.; Tomilin, F. N.; Томилин, Феликс Николаевич; Zabluda, V. N.; Заблуда, Владимир Николаевич; Alekhina, Yu.; Lukyanenko, K. A.; Glazyrin, Yu. E.; Svetlichnyi, V. A.; Berezovski, M. V.; Kichkailo, A. S.
}
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15.
Theoretical DFT interpretation
of infrared spectra of biologically active
arabinogalactan
sulphated derivatives / A. S. Kazachenko, F. N. Tomilin, A. A. Pozdnyakova [et al.]> // Chem. Pap. - 2020. -
Vol. 74
,
Is. 11
. - P. 4103-4113,
DOI
10.1007/s11696-020-01220-3. - Cited References: 52. - The reported work was funded by RFBR and the government of Krasnoyarsk region according to the research project. 18-43-242003. The study was carried out using equipment of the Krasnoyarsk Regional Center of Research Equipment, Federal Research Center "Krasnoyarsk Science Center SB RAS". Publication was also partially supported by Project FSWM-2020-0033 of Russian Ministry of Science and Education.The authors are grateful to I.V. Korolkova for IR-spectra. . - ISSN 2585-7290. - ISSN 1336-9075
РУБ
Chemistry, Multidisciplinary
Рубрики:
DENSITY-FUNCTIONAL THEORIES
ASTRAGALUS POLYSACCHARIDE
ANTICOAGULANT
Кл.слова (ненормированные):
Arabinogalactan
--
Sulphated
arabinogalactan
--
FTIR-spectra
--
Molecular structure
--
Density functional theory
Аннотация:
Arabinogalactan
(AG) and sulphated arabinogalactans which are products of chemical modification of
arabinogalactan
polysaccharide with anticoagulant properties were studied by experimental infrared (IR) spectroscopy combined with density functional theory simulations. Mutual analysis of experimental and theoretical IR frequencies indicates that the discrepancies between experiment and theory is caused by the influence of –OH groups, which led to the energy shift and broadening of the absorption IR bands. It was found that theoretical and experimental spectra correspond well within the 3000–4000 cm−1 spectral region. Addition of sulphur group in AG structure causes hydroxyl group to become accessible for further sulphation. The difference between experimental and theoretical IR frequencies of sulphated AG derivatives is greater than that of the parent
arabinogalactan
due to the increase in the number of possible isomers and conformers.
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Держатели документа:
FRC Krasnoyarsk Sci Ctr SB RAS, Inst Chem & Chem Technol SB RAS, 50-24 Akademgorodok, Krasnoyarsk 660036, Russia.
Siberian Fed Univ, 79 Svobodny Pr, Krasnoyarsk 660041, Russia.
FRC Krasnoyarsk Sci Ctr SB RAS, Kirensky Inst Phys SB RAS, 50-38 Akademgorodok, Krasnoyarsk 660036, Russia.
Natl Res Tomsk State Univ, Lenin Ave 36, Tomsk 634050, Russia.
Kyungpook Natl Univ, Dept Chem, 80 Daehak Ro, Daegu 41566, South Korea.
Kyungpook Natl Univ, Green Nano Mat Res Ctr, 80 Daehak Ro, Daegu 41566, South Korea.
Доп.точки доступа:
Kazachenko, Aleksandr S.; Tomilin, F. N.; Томилин, Феликс Николаевич; Pozdnyakova, Anastasia A.; Vasilyeva, Natalia Yu; Malyar, Yuriy N.; Kuznetsova, Svetlana A.; Avramov, P. V.; Аврамов, Павел Вениаминович; RFBRRussian Foundation for Basic Research (RFBR); government of Krasnoyarsk region [18-43-242003]; Russian Ministry of Science and EducationMinistry of Education and Science, Russian Federation [FSWM-2020-0033]
}
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16.
Nanocomposite FeCo films
based on
arabinogalactan
: synthesis and magnetic properties / L. A. Chekanova [et al.]> //
Euro-asian symposium "Trends in magnetism" (EASTMAG-2019) : Book of abstracts / чл. конс. ком.: S. G. Ovchinnikov, N. V. Volkov [et al.] ; чл. прогр. ком. D. M. Dzebisashvili [et al.]. - 2019. -
Vol. 2
. - Ст. J.P36. - P. 250-251. - Cited References: 5. - This work was supported by Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research project No. 18-42-240006 . - ISBN 978-5-9500855-7-4
Перевод заглавия:
Нанокомпозитные FeCo пленки на основе арабиногалактана: синтез и магнитные свойства
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Держатели документа:
Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Krasnoyarsk, Russia
Federal Research Center KSC SB RAS, Krasnoyarsk, Russia
Siberian Federal University, Krasnoyarsk, Russia
Доп.точки доступа:
Ovchinnikov, S. G. \чл. конс. ком.\; Овчинников, Сергей Геннадьевич; Volkov, N. V. \чл. конс. ком.\; Волков, Никита Валентинович; Dzebisashvili, D. M. \чл. прогр. ком.\; Дзебисашвили, Дмитрий Михайлович; Chekanova, L. A.; Чеканова, Лидия Александровна; Denisova, E. A.; Денисова, Елена Александровна; Komogortsev, S. V.; Комогорцев, Сергей Викторович; Iskhakov, R. S.; Исхаков, Рауф Садыкович; Nemtsev, I. V.; Немцев, Иван Васильевич; Volochaev, M. N.; Волочаев, Михаил Николаевич; Российская академия наук; Уральское отделение РАН; Институт физики металлов им. М. Н. Михеева Уральского отделения РАН; Уральский федеральный университет им. первого Президента России Б.Н. Ельцина; Российский фонд фундаментальных исследований; Euro-Asian Symposium "Trends in MAGnetism"(7 ; 2019 ; Sept. ; 8-13 ; Ekaterinburg); "Trends in MAGnetism", Euro-Asian Symposium(7 ; 2019 ; Sept. ; 8-13 ; Ekaterinburg)
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17.
Magnetic coatings of
Fe synthesized with
arabinogalactan
/ S. V. Stolyar [и др.]> //
Euro-asian symposium "Trends in magnetism" (EASTMAG-2019) : Book of abstracts / чл. конс. ком.: S. G. Ovchinnikov, N. V. Volkov [et al.] ; чл. прогр. ком. D. M. Dzebisashvili [et al.]. - 2019. -
Vol. 2
. - Ст. M.P10. - P. 504-505. - Cited References: 4. - The reported study was carried out with the financial support of the Russian Foundation for Fundamental Research, the Government of the Krasnoyarsk Territory, the Krasnoyarsk Territory Fund for Support of Scientific and Technical Activity in the framework of scientific Project No. 18-43-243003. The work is supported by the Special Program of the Ministry of Education and Science of the Russian Federation for the Siberian Federal University . - ISBN 978-5-9500855-7-4
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Держатели документа:
Kirensky Institute of Physics, Federal Research Center KSC SB RAS, Krasnoyarsk, Russia
Federal Research Center KSC SB RAS, Krasnoyarsk, Russia
Siberian Federal University, Krasnoyarsk, Russia
Доп.точки доступа:
Ovchinnikov, S. G. \чл. конс. ком.\; Овчинников, Сергей Геннадьевич; Volkov, N. V. \чл. конс. ком.\; Волков, Никита Валентинович; Dzebisashvili, D. M. \чл. прогр. ком.\; Дзебисашвили, Дмитрий Михайлович; Stolyar, S. V.; Столяр, Сергей Викторович; Chekanova, L. A.; Чеканова, Лидия Александровна; Cheremiskina, E. V.; Bayukov, O. A.; Баюков, Олег Артемьевич; Yaroslavtsev, R. N.; Ярославцев, Роман Николаевич; Iskhakov, R. S.; Исхаков, Рауф Садыкович; Российская академия наук; Уральское отделение РАН; Институт физики металлов им. М. Н. Михеева Уральского отделения РАН; Уральский федеральный университет им. первого Президента России Б.Н. Ельцина; Российский фонд фундаментальных исследований; Euro-Asian Symposium "Trends in MAGnetism"(7 ; 2019 ; Sept. ; 8-13 ; Ekaterinburg); "Trends in MAGnetism", Euro-Asian Symposium(7 ; 2019 ; Sept. ; 8-13 ; Ekaterinburg)
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